日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Generation of APOE knock-down SK-N-SH human neuroblastoma cells using CRISPR/Cas9: a novel cellular model relevant to Alzheimer's disease research

使用 CRISPR/Cas9 生成 APOE 敲低的 SK-N-SH 人类神经母细胞瘤细胞:一种与阿尔茨海默病研究相关的新型细胞模型

Sonia Sanz Muñoz, Brett Garner, Lezanne Ooi

Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease

鞘氨醇激酶2可增强淀粉样蛋白沉积,但在阿尔茨海默病小鼠模型中可防止海马体积减少和脱髓鞘。

Mona Lei ,Jonathan D Teo ,Huitong Song ,Holly P McEwen ,Jun Yup Lee ,Timothy A Couttas ,Thomas Duncan ,Rose Chesworth ,Josefine Bertz ,Magdalena Przybyla ,Janet Van Eersel ,Benjamin Heng ,Gilles J Guillemin ,Lars M Ittner ,Thomas Fath ,Brett Garner ,Arne Ittner ,Tim Karl ,Anthony S Don

The serine protease HtrA1 contributes to the formation of an extracellular 25-kDa apolipoprotein E fragment that stimulates neuritogenesis

丝氨酸蛋白酶 HtrA1 有助于形成细胞外 25 kDa 载脂蛋白 E 片段,从而刺激神经突发生

Sonia Sanz Muñoz, Hongyun Li, Kalani Ruberu, Qian Chu, Alan Saghatelian, Lezanne Ooi, Brett Garner

Beneficial effects of increased lysozyme levels in Alzheimer's disease modelled in Drosophila melanogaster

溶菌酶水平升高对果蝇阿尔茨海默病模型的有益影响

Linnea Sandin, Liza Bergkvist, Sangeeta Nath, Claudia Kielkopf, Camilla Janefjord, Linda Helmfors, Henrik Zetterberg, Kaj Blennow, Hongyun Li, Camilla Nilsberth, Brett Garner, Ann-Christin Brorsson, Katarina Kågedal

Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue

亨廷顿氏病患者死后脑组织胆固醇代谢改变的证据

Fabian Kreilaus, Adena S Spiro, Catriona A McLean, Brett Garner, Andrew M Jenner

Abca7 deletion does not affect adult neurogenesis in the mouse

Abca7 缺失不会影响小鼠成年神经发生

Hongyun Li, Tim Karl, Brett Garner

Cell Type-Specific Modulation of Cobalamin Uptake by Bovine Serum

细胞类型特异性调节牛血清中的钴胺素吸收

Hua Zhao, Kalani Ruberu, Hongyun Li, Brett Garner

Cerebral Apolipoprotein-D Is Hypoglycosylated Compared to Peripheral Tissues and Is Variably Expressed in Mouse and Human Brain Regions

与外周组织相比,脑载脂蛋白 D 糖基化程度较低,且在小鼠和人类脑区有不同程度的表达

Hongyun Li, Kalani Ruberu, Tim Karl, Brett Garner

Apolipoprotein D modulates amyloid pathology in APP/PS1 Alzheimer's disease mice

载脂蛋白 D 调节 APP/PS1 阿尔茨海默病小鼠的淀粉样蛋白病理

Hongyun Li, Kalani Ruberu, Sonia Sanz Muñoz, Andrew M Jenner, Adena Spiro, Hua Zhao, Eric Rassart, Diego Sanchez, Maria D Ganfornina, Tim Karl, Brett Garner

Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease

散发性帕金森病中葡萄糖脑苷脂酶降低与 α-突触核蛋白增加有关

Karen E Murphy, Amanda M Gysbers, Sarah K Abbott, Nahid Tayebi, Woojin S Kim, Ellen Sidransky, Antony Cooper, Brett Garner, Glenda M Halliday