日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of Two Structurally Distinct Classes of Inhibitors Targeting the Nuclease MUS81 and Enhancing Efficacy of Chemotherapy in Cancer Cells

发现两类结构不同的MUS81核酸酶抑制剂，可增强化疗对癌细胞的疗效

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c02096
Prochazkova, Jana; Carbain, Benoit; Marini, Victoria; Nikulenkov, Fedor; Havel, Stepan; Akavaram, Naresh; Khirsariya, Prashant; Sisakova, Alexandra; Cibulka, Jakub; Boudova, Michala; Zacpalova, Magdalena; Kalovska, Magdalena; Rodrigues, Joana; Daniel, Lukas; Brezovsky, Jan; Bartunek, Petr; Azzalin, Claus; Paruch, Kamil; Krejci, Lumir
MUS81
细胞生物学
肿瘤
肿瘤免疫
发表日期：2026
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Message hidden in α-helices-toward a better understanding of plant ABCG transporters' multispecificity

α螺旋中隐藏的信息——更好地理解植物ABCG转运蛋白的多特异性

期刊:Plant Physiology
影响因子:6.9
doi:10.1093/plphys/kiaf146
Biała-Leonhard, Wanda; Bigos, Aleksandra; Brezovsky, Jan; Jasiński, Michał
发表日期：2025
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Incorporating Prior Knowledge in the Seeds of Adaptive Sampling Molecular Dynamics Simulations of Ligand Transport in Enzymes with Buried Active Sites

将先验知识融入具有埋藏活性位点的酶的配体运输的自适应采样分子动力学模拟种子中

期刊:Journal of Chemical Theory and Computation
影响因子:5.5
doi:10.1021/acs.jctc.4c00452
Sarkar, Dheeraj Kumar; Surpeta, Bartlomiej; Brezovsky, Jan
发表日期：2024
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Reinforcing Tunnel Network Exploration in Proteins Using Gaussian Accelerated Molecular Dynamics

利用高斯加速分子动力学增强蛋白质中的隧道网络探索

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.4c00966
Mandal, Nishita; Surpeta, Bartlomiej; Brezovsky, Jan
发表日期：2024
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Water will Find Its Way: Transport through Narrow Tunnels in Hydrolases

水会找到出路：水解酶中通过狭窄隧道进行运输

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.4c00094
Sequeiros-Borja, Carlos; Surpeta, Bartlomiej; Thirunavukarasu, Aravind Selvaram; Dongmo Foumthuim, Cedrix J; Marchlewski, Igor; Brezovsky, Jan
发表日期：2024
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Impact of water models on the structure and dynamics of enzyme tunnels

水模型对酶通道结构和动力学的影响

期刊:Computational and Structural Biotechnology Journal
影响因子:4.1
doi:10.1016/j.csbj.2024.10.051
Sethi, Aaftaab; Agrawal, Nikhil; Brezovsky, Jan
发表日期：2024
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Restriction of access to the central cavity is a major contributor to substrate selectivity in plant ABCG transporters

限制进入中央腔是植物ABCG转运蛋白底物选择性的主要因素。

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-023-04751-6
Pakuła, Konrad; Sequeiros-Borja, Carlos; Biała-Leonhard, Wanda; Pawela, Aleksandra; Banasiak, Joanna; Bailly, Aurélien; Radom, Marcin; Geisler, Markus; Brezovsky, Jan; Jasiński, Michał
发表日期：2023
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Divide-and-conquer approach to study protein tunnels in long molecular dynamics simulations

采用分而治之的方法研究长时间分子动力学模拟中的蛋白质隧道

期刊:MethodsX
影响因子:1.9
doi:10.1016/j.mex.2022.101968
Sequeiros-Borja, Carlos; Surpeta, Bartlomiej; Marchlewski, Igor; Brezovsky, Jan
发表日期：2023
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Recent advances in user-friendly computational tools to engineer protein function

近年来，易于使用的计算工具在蛋白质功能工程方面取得了显著进展。

期刊:Briefings in Bioinformatics
影响因子:7.7
doi:10.1093/bib/bbaa150
Sequeiros-Borja, Carlos Eduardo; Surpeta, Bartłomiej; Brezovsky, Jan
发表日期：2021
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A Quantum Annealing Algorithm for Finding Pure Nash Equilibria in Graphical Games

一种用于寻找图博弈中纯纳什均衡的量子退火算法

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.4c01177
Thirunavukarasu, Aravind Selvaram; Szleper, Katarzyna; Tanriver, Gamze; Marchlewski, Igor; Mitusinska, Karolina; Gora, Artur; Brezovsky, Jan; Roch, Christoph; Phan, Thomy; Feld, Sebastian; Müller, Robert; Gabor, Thomas; Hahn, Carsten; Linnhoff-Popien, Claudia
发表日期：2020
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