日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A recombinant Cedar virus preclinical model that recapitulates neurological features of henipavirus disease

一种重组雪松病毒临床前模型,可重现亨尼帕病毒病的神经系统特征

Celeste Huaman ,Caitlyn Clouse ,Madeline Rader ,Allison M Strazzella ,Jocelyn King ,Elise M Santorella ,Lianying Yan ,Shuangyi Bai ,Bronwyn M Gunn ,Moushimi Amaya ,Christopher C Broder ,Brian C Schaefer

A20 intrinsically influences human effector T-cell survival and function by regulating both NF-κB and JNK signaling

A20 通过调节 NF-κB 和 JNK 信号通路,从内在层面影响人类效应 T 细胞的存活和功能。

Gina Dabbah-Krancher ,Allison Ruchinskas ,Melissa A Kallarakal ,Katherine P Lee ,Bradly M Bauman ,Benjamin Epstein ,Hongli Yin ,Daniel Krappmann ,Brian C Schaefer ,Andrew L Snow

An in vivo BSL-2 model for henipavirus infection based on bioluminescence imaging of recombinant Cedar virus replication in mice

基于小鼠重组雪松病毒复制的生物发光成像的亨尼巴病毒感染体内BSL-2模型

Celeste Huaman, Caitlyn Clouse, Madeline Rader, Lianying Yan, Shuangyi Bai, Bronwyn M Gunn, Moushimi Amaya, Eric D Laing, Christopher C Broder, Brian C Schaefer

mAb therapy controls CNS-resident lyssavirus infection via a CD4 T cell-dependent mechanism

mAb疗法通过CD4 T细胞依赖性机制控制中枢神经系统驻留的狂犬病毒感染。

Kate E Mastraccio # ,Celeste Huaman # ,Si'Ana A Coggins ,Caitlyn Clouse ,Madeline Rader ,Lianying Yan ,Pratyusha Mandal ,Imran Hussain ,Anwar E Ahmed ,Trung Ho ,Austin Feasley ,Bang K Vu ,Ina L Smith ,Wanda Markotter ,Dawn L Weir ,Eric D Laing ,Christopher C Broder ,Brian C Schaefer

CARD19 Interacts with Mitochondrial Contact Site and Cristae Organizing System Constituent Proteins and Regulates Cristae Morphology

CARD19 与线粒体接触位点和嵴组织系统组成蛋白相互作用并调节嵴形态

Kariana E Rios, Ming Zhou, Nathaniel M Lott, Chelsi R Beauregard, Dennis P McDaniel, Thomas P Conrads, Brian C Schaefer

Bcl10 is associated with actin dynamics at the T cell immune synapse

Bcl10 与 T 细胞免疫突触处的肌动蛋白动力学有关

Kaustubh Wagh, Brittany A Wheatley, Maria K Traver, Imran Hussain, Brian C Schaefer, Arpita Upadhyaya

CARD19, the protein formerly known as BinCARD, is a mitochondrial protein that does not regulate Bcl10-dependent NF-κB activation after TCR engagement

CARD19(曾用名 BinCARD)是一种线粒体蛋白,在 TCR 激活后不调节 Bcl10 依赖的 NF-κB 激活。

Kariana E Rios,Anuj K Kashyap,Sean K Maynard,Michael Washington,Suman Paul,Brian C Schaefer

CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment

CARD9+ 小胶质细胞通过 IL-1β 和 CXCL1 介导的中性粒细胞募集促进抗真菌免疫

Rebecca A Drummond, Muthulekha Swamydas #, Vasileios Oikonomou #, Bing Zhai #, Ivy M Dambuza, Brian C Schaefer, Andrea C Bohrer, Katrin D Mayer-Barber, Sergio A Lira, Yoichiro Iwakura, Scott G Filler, Gordon D Brown, Bernhard Hube, Julian R Naglik, Tobias M Hohl, Michail S Lionakis

Enhanced Autophagy Contributes to Reduced Viral Infection in Black Flying Fox Cells

增强自噬有助于减少黑狐蝠细胞中的病毒感染

Eric D Laing, Spencer L Sterling, Dawn L Weir, Chelsi R Beauregard, Ina L Smith, Sasha E Larsen, Lin-Fa Wang, Andrew L Snow, Brian C Schaefer, Christopher C Broder

Intrinsic Differences in Donor CD4 T Cell IL-2 Production Influence Severity of Parent-into-F1 Murine Lupus by Skewing the Immune Response Either toward Help for B Cells and a Sustained Autoantibody Response or toward Help for CD8 T Cells and a Downregulatory Th1 Response

供体 CD4 T 细胞 IL-2 产生的内在差异会影响亲代至 F1 鼠类狼疮的严重程度,方法是使免疫反应偏向于帮助 B 细胞和持续的自身抗体反应,或偏向于帮助 CD8 T 细胞和下调的 Th1 反应

Kateryna Soloviova, Maksym Puliaiev, Mark Haas, Clifton L Dalgard, Brian C Schaefer, Charles S Via