日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Divergent populations of HIV-infected naive and memory CD4+ T cell clones in children on antiretroviral therapy

接受抗逆转录病毒治疗的儿童体内存在不同的HIV感染的初始和记忆性CD4+ T细胞克隆群

Mary Grace Katusiime ,Victoria Neer ,Shuang Guo ,Sean C Patro ,Wenjie Wang ,Brian Luke ,Adam A Capoferri ,Xiaolin Wu ,Anna M Horner ,Jason W Rausch ,Ann Chahroudi ,Maud Mavigner ,Mary F Kearney

Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence

端粒转录应激导致胞质DNA释放和旁分泌衰老

Athanasios Siametis # ,Kalliopi Stratigi # ,Despoina Giamaki ,Georgia Chatzinikolaou ,Alexia Akalestou-Clocher ,Evi Goulielmaki ,Brian Luke ,Björn Schumacher ,George A Garinis

Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase

修复 S 期单基因组核苷酸引起的损伤的遗传要求

Natalie Schindler #, Matthias Tonn #, Vanessa Kellner, Jia Jun Fung, Arianna Lockhart, Olga Vydzhak, Thomas Juretschke, Stefanie Möckel, Petra Beli, Anton Khmelinskii, Brian Luke

DNA damage repair proteins across the Tree of Life

生命之树中的 DNA 损伤修复蛋白

Emily Nischwitz, Vivien A C Schoonenberg, Albert Fradera-Sola, Mario Dejung, Olga Vydzhak, Michal Levin, Brian Luke, Falk Butter, Marion Scheibe

Mre11-Rad50 oligomerization promotes DNA double-strand break repair

Mre11-Rad50寡聚化促进DNA双链断裂修复

Vera M Kissling, Giordano Reginato #, Eliana Bianco #, Kristina Kasaciunaite, Janny Tilma, Gea Cereghetti, Natalie Schindler, Sung Sik Lee, Raphaël Guérois, Brian Luke, Ralf Seidel, Petr Cejka, Matthias Peter

Metabolic remodeling maintains a reducing environment for rapid activation of the yeast DNA replication checkpoint

代谢重塑维持还原环境,以快速激活酵母 DNA 复制检查点

Lili Li, Jie Wang, Zijia Yang, Yiling Zhao, Hui Jiang, Luguang Jiang, Wenya Hou, Risheng Ye, Qun He, Martin Kupiec, Brian Luke, Qinhong Cao, Zhi Qi, Zhen Li, Huiqiang Lou

R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability

环邻近蛋白质组学确定了 DDX41 在转录相关基因组不稳定性中的作用

Thorsten Mosler, Francesca Conte, Gabriel M C Longo, Ivan Mikicic, Nastasja Kreim, Martin M Möckel, Giuseppe Petrosino, Johanna Flach, Joan Barau, Brian Luke, Vassilis Roukos, Petra Beli

Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy

在抑制性抗逆转录病毒治疗之前或期间,癌基因的整合在确定 HIV 整合位点的体内分布方面仅起着次要作用

John M Coffin, Michael J Bale, Daria Wells, Shuang Guo, Brian Luke, Jennifer M Zerbato, Michele D Sobolewski, Twan Sia, Wei Shao, Xiaolin Wu, Frank Maldarelli, Mary F Kearney, John W Mellors, Stephen H Hughes

Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio

叶酰聚谷氨酸合成酶 Met7 失活导致 dUTP/dTTP 比率增加,从而引起基因组不稳定

Tobias T Schmidt, Sushma Sharma, Gloria X Reyes, Anna Kolodziejczak, Tina Wagner, Brian Luke, Anders Hofer, Andrei Chabes, Hans Hombauer

Npl3 stabilizes R-loops at telomeres to prevent accelerated replicative senescence

Npl3 稳定端粒处的 R 环,以防止加速复制衰老

Lara Pérez-Martínez, Merve Öztürk, Falk Butter, Brian Luke