日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Myofilament-based physiological regulatory compensation preserves diastolic function in failing hearts with severe Ca2+ handling deficits

基于肌丝的生理调节补偿可维持严重 Ca2+ 处理缺陷的衰竭心脏的舒张功能

Frazer I Heinis, Brian R Thompson, Rishi Gulati, Matthew Wheelwright, Joseph M Metzger

Inducing positive inotropy in human iPSC-derived cardiac muscle by gene editing-based activation of the cardiac α-myosin heavy chain

通过基于基因编辑的心脏 α-肌球蛋白重链激活,在人类 iPSC 衍生的心肌中诱导正性肌力

Fikru B Bedada, Brian R Thompson, Jennifer L Mikkila, Sunny S-K Chan, Si Ho Choi, Erik A Toso, Michael Kyba, Joseph M Metzger

Rapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers

合成共聚物可快速恢复缺乏肌营养不良蛋白的单个活骨骼肌纤维的收缩功能障碍

Dongwoo Hahn, Joseph D Quick, Brian R Thompson, Adelyn Crabtree, Benjamin J Hackel, Frank S Bates, Joseph M Metzger

Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers

肌丝集成 FRET 生物传感器揭示活体骨骼肌纤维中的肌节动力学

Ashley A Martin, Brian R Thompson, Jonathan P Davis, Hluechy Vang, Dongwoo Hahn, Joseph M Metzger

Oxidative stress pathogenically remodels the cardiac myocyte cytoskeleton via structural alterations to the microtubule lattice

氧化应激通过改变微管晶格的结构,致病性地重塑心肌细胞骨架

Rebecca R Goldblum, Mark McClellan, Kyle White, Samuel J Gonzalez, Brian R Thompson, Hluechy X Vang, Houda Cohen, LeeAnn Higgins, Todd W Markowski, Tzu-Yi Yang, Joseph M Metzger, Melissa K Gardner

Advancing physiological maturation in human induced pluripotent stem cell-derived cardiac muscle by gene editing an inducible adult troponin isoform switch

通过基因编辑可诱导的成人肌钙蛋白异构体转换来促进人类诱导性多能干细胞衍生的心肌的生理成熟

Matthew Wheelwright, Jennifer Mikkila, Fikru B Bedada, Mohammad A Mandegar, Brian R Thompson, Joseph M Metzger

Long-Term Renal Function Recovery following Radical Nephrectomy for Kidney Cancer: Results from a Multicenter Confirmatory Study

肾癌根治性肾切除术后长期肾功能恢复:一项多中心验证性研究的结果

Zabor, Emily C; Furberg, Helena; Lee, Byron; Campbell, Steven; Lane, Brian R; Thompson, R Houston; Antonio, Elvis Caraballo; Noyes, Sabrina L; Zaid, Harras; Jaimes, Edgar A; Russo, Paul

TnI Structural Interface with the N-Terminal Lobe of TnC as a Determinant of Cardiac Contractility

TnI 结构界面与 TnC N 端叶作为心脏收缩力的决定因素

Anthony D Vetter, Evelyne M Houang, Jordan J Sell, Brian R Thompson, Yuk Y Sham, Joseph M Metzger

Variability of inter-observer agreement on feasibility of partial nephrectomy before and after neoadjuvant axitinib for locally advanced renal cell carcinoma (RCC): independent analysis from a phase II trial

新辅助阿昔替尼治疗局部晚期肾细胞癌(RCC)前后行部分肾切除术可行性的观察者间一致性差异:一项II期试验的独立分析

Karam, Jose A; Devine, Catherine E; Fellman, Bryan M; Urbauer, Diana L; Abel, E Jason; Allaf, Mohamad E; Bex, Axel; Lane, Brian R; Thompson, R Houston; Wood, Christopher G