CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands.
CARD9 通过改变肠道菌群将色氨酸代谢为芳烃受体配体来影响结肠炎
期刊:Nature Medicine
影响因子:50
doi:10.1038/nm.4102
Lamas Bruno, Richard Mathias L, Leducq Valentin, Pham Hang-Phuong, Michel Marie-Laure, Da Costa Gregory, Bridonneau Chantal, Jegou Sarah, Hoffmann Thomas W, Natividad Jane M, Brot Loic, Taleb Soraya, Couturier-Maillard Aurélie, Nion-Larmurier Isabelle, Merabtene Fatiha, Seksik Philippe, Bourrier Anne, Cosnes Jacques, Ryffel Bernhard, Beaugerie Laurent, Launay Jean-Marie, Langella Philippe, Xavier Ramnik J, Sokol Harry