CRISPR/Cas9-mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients
CRISPR/Cas9 介导的 ELANE 敲除可使严重先天性中性粒细胞减少症患者的原代造血干细胞和祖细胞以及诱导性多能干细胞实现中性粒细胞成熟
期刊:Haematologica
影响因子:8.2
doi:10.3324/haematol.2019.221804
Masoud Nasri, Malte Ritter, Perihan Mir, Benjamin Dannenmann, Narges Aghaallaei, Diana Amend, Vahagn Makaryan, Yun Xu, Breanna Fletcher, Regine Bernhard, Ingeborg Steiert, Karin Hahnel, Jürgen Berger, Iris Koch, Brigitte Sailer, Katharina Hipp, Cornelia Zeidler, Maksim Klimiankou, Baubak Bajoghli, D
