日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficient in vivo mammalian neuron editing using peptide-mediated CRISPR enzyme delivery

利用肽介导的CRISPR酶递送实现高效的体内哺乳动物神经元编辑

Manohar, Brigette D; Travis, Meika; Munjal, Vikas; Baehr, Christopher M; Rahnama, Lily M A; Kang, Min Hyung; Haddad, Rania F; Asija, Kunica; Noel, Eric A; Peddireddy, Navya; Chouhan, Runvir S; Sharma, Rohit; Wyman, Stacia K; Krishnappa, Netravathi; Killebrew, Deirdre A; Li, Song Hua; Snow, Kathy J; Byrne, Addison K; Boosani, Chandra S; Otero, P Anthony; Bringas, John; O'Brien, Allison A; Rocco, Matthew T; Zimmerly, Madison P; Gray, Isabelle; Sran, Gunita K; Patel, Mia I; Seidensticker, Emily F; Saville, Ethan; Gaitan, Yaned; Schmelzle, Amanda L; Subramanyam, Pradeep Nag B; Samaranch, Lluis; Green, Jonathan A; Wells, Kevin D; Ehrenberg, Alexander J; Murray, Stephen A; Clelland, Claire D; Murthy, Niren; Lonser, Russell R; Hadaczek, Piotr; Van Laar, Victor S; Bankiewicz, Krystof S; Wilson, Ross C

SetD7 (Set7/9) is a novel target of PPARγ that promotes the adaptive pancreatic β-cell glycemic response

SetD7 (Set7/9) 是 PPARγ 的一个新靶点,可促进胰腺 β 细胞适应性血糖反应

Thomas L Jetton, Patricio Flores-Bringas, John L Leahy, Dhananjay Gupta

Development of a novel frameless skull-mounted ball-joint guide array for use in image-guided neurosurgery

开发一种新型的无框架颅骨安装式球形关节导向阵列,用于图像引导神经外科手术

Sudhakar, Vivek; Mahmoodi, Amin; Bringas, John R; Naidoo, Jerusha; Kells, Adrian; Samaranch, Lluis; Fiandaca, Massimo S; Bankiewicz, Krystof S

Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates

非人灵长类动物脑脊液中AAV9载体递送的动力学和基于磁共振的监测

Ohno, Kousaku; Samaranch, Lluis; Hadaczek, Piotr; Bringas, John R; Allen, Philip C; Sudhakar, Vivek; Stockinger, Diane E; Snieckus, Christopher; Campagna, Michael V; San Sebastian, Waldy; Naidoo, Jerusha; Chen, Haifeng; Forsayeth, John; Salegio, Ernesto A; Hwa, Granger G C; Bankiewicz, Krystof S

Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease

非人灵长类动物大脑中广泛的AAV1和AAV2介导的转基因表达:对亨廷顿病的启示

Hadaczek, Piotr; Stanek, Lisa; Ciesielska, Agnieszka; Sudhakar, Vivek; Samaranch, Lluis; Pivirotto, Philip; Bringas, John; O'Riordan, Catherine; Mastis, Bryan; San Sebastian, Waldy; Forsayeth, John; Cheng, Seng H; Bankiewicz, Krystof S; Shihabuddin, Lamya S

Cerebellomedullary Cistern Delivery for AAV-Based Gene Therapy: A Technical Note for Nonhuman Primates

基于腺相关病毒(AAV)的基因治疗的小脑延髓池递送:非人灵长类动物技术说明

Samaranch, Lluis; Bringas, John; Pivirotto, Philip; Sebastian, Waldy San; Forsayeth, John; Bankiewicz, Krystof

AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction.

在非人灵长类动物中枢神经系统中,AAV9 介导的非自身蛋白表达会引发由抗原呈递细胞转导驱动的广泛神经炎症

Samaranch Lluis, Sebastian Waldy San, Kells Adrian P, Salegio Ernesto A, Heller Gregory, Bringas John R, Pivirotto Philip, DeArmond Stephen, Forsayeth John, Bankiewicz Krystof S

Dynamic hyperpolarized carbon-13 MR metabolic imaging of nonhuman primate brain

非人灵长类动物脑部的动态超极化碳-13磁共振代谢成像

Park, Ilwoo; Larson, Peder E Z; Tropp, James L; Carvajal, Lucas; Reed, Galen; Bok, Robert; Robb, Fraser; Bringas, John; Kells, Adrian; Pivirotto, Philip; Bankiewicz, Krystof; Vigneron, Daniel B; Nelson, Sarah J

Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy

纳米颗粒在啮齿动物和非人灵长类动物大脑皮层的分布:对基因和药物治疗的启示

Salegio, Ernesto A; Streeter, Hillary; Dube, Nikhil; Hadaczek, Piotr; Samaranch, Lluis; Kells, Adrian P; San Sebastian, Waldy; Zhai, Yuying; Bringas, John; Xu, Ting; Forsayeth, John; Bankiewicz, Krystof S

Strong cortical and spinal cord transduction after AAV7 and AAV9 delivery into the cerebrospinal fluid of nonhuman primates

AAV7 和 AAV9 递送至非人类灵长类动物脑脊液后,皮质和脊髓发生强转导

Lluis Samaranch, Ernesto A Salegio, Waldy San Sebastian, Adrian P Kells, John R Bringas, John Forsayeth, Krystof S Bankiewicz