Brogley相关文献与解析，生知库 | 链接生命科学的每一步

Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element

前列腺癌治疗中雄激素受体的差异调节取决于 DNA 反应元件

Steven Kregel, Pia Bagamasbad, Shihan He, Elizabeth LaPensee, Yemi Raji, Michele Brogley, Arul Chinnaiyan, Marcin Cieslik, Diane M Robins

肿瘤

前列腺癌

发表日期：2020

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Genomic Structure, Evolutionary Origins, and Reproductive Function of a Large Amplified Intrinsically Disordered Protein-Coding Gene on the X Chromosome (Laidx) in Mice

小鼠 X 染色体上大型扩增内在无序蛋白质编码基因 (Laidx) 的基因组结构、进化起源和生殖功能

期刊:G3-Genes Genomes Genetics

影响因子:

doi:10.1534/g3.120.401221

Martin F Arlt, Michele A Brogley, Evan R Stark-Dykema, Yueh-Chiang Hu, Jacob L Mueller

信号转导

发表日期：2020

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A Neofunctionalized X-Linked Ampliconic Gene Family Is Essential for Male Fertility and Equal Sex Ratio in Mice

新功能化的 X 连锁扩增子基因家族对小鼠雄性生育能力和性别比例至关重要

期刊:Current Biology

影响因子:8.1

doi:10.1016/j.cub.2019.08.057

Alyssa N Kruger, Michele A Brogley, Jamie L Huizinga, Jeffrey M Kidd, Dirk G de Rooij, Yueh-Chiang Hu, Jacob L Mueller

Male mice with large inversions or deletions of X-chromosome palindrome arms are fertile and express their associated genes during post-meiosis

雄性小鼠若X染色体回文臂发生大片段倒位或缺失，则仍具有生育能力，并在减数分裂后表达其相关基因。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-018-27360-x

Kruger, Alyssa N; Ellison, Quinn; Brogley, Michele A; Gerlinger, Emma R; Mueller, Jacob L

发表日期：2018

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Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression

小鼠前列腺中雄激素受体、ETV1 和 PTEN 通路的相互作用随病理阶段而变化并可预测癌症进展

期刊:Hormones & Cancer

影响因子:

doi:10.1007/s12672-014-0215-9

Jake Higgins, Michele Brogley, Nallasivam Palanisamy, Rohit Mehra, Michael M Ittmann, Jun Z Li, Scott A Tomlins, Diane M Robins

Length of the human androgen receptor glutamine tract determines androgen sensitivity in vivo

人雄激素受体谷氨酰胺链的长度决定了体内雄激素敏感性。

期刊:Molecular and Cellular Endocrinology

影响因子:3.6

doi:10.1016/j.mce.2011.05.011

Simanainen, Ulla; Brogley, Michele; Gao, Yan Ru; Jimenez, Mark; Harwood, D Tim; Handelsman, David J; Robins, Diane M

Profiling human androgen receptor mutations reveals treatment effects in a mouse model of prostate cancer

对人类雄激素受体突变进行分析揭示了前列腺癌小鼠模型中的治疗效果

期刊:Molecular Cancer Research

影响因子:4.7

doi:10.1158/1541-7786.MCR-08-0273

O'Mahony, Orla A; Steinkamp, Mara P; Albertelli, Megan A; Brogley, Michele; Rehman, Haniya; Robins, Diane M

Back to the Future: Long-Term Leadership Lessons From the COVID-19 Pandemic

回到未来：从新冠疫情中汲取的长期领导力经验

Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element

前列腺癌治疗中雄激素受体的差异调节取决于 DNA 反应元件

Genomic Structure, Evolutionary Origins, and Reproductive Function of a Large Amplified Intrinsically Disordered Protein-Coding Gene on the X Chromosome (Laidx) in Mice

小鼠 X 染色体上大型扩增内在无序蛋白质编码基因 (Laidx) 的基因组结构、进化起源和生殖功能

A Neofunctionalized X-Linked Ampliconic Gene Family Is Essential for Male Fertility and Equal Sex Ratio in Mice

新功能化的 X 连锁扩增子基因家族对小鼠雄性生育能力和性别比例至关重要

Male mice with large inversions or deletions of X-chromosome palindrome arms are fertile and express their associated genes during post-meiosis

雄性小鼠若X染色体回文臂发生大片段倒位或缺失，则仍具有生育能力，并在减数分裂后表达其相关基因。

Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression

小鼠前列腺中雄激素受体、ETV1 和 PTEN 通路的相互作用随病理阶段而变化并可预测癌症进展

Length of the human androgen receptor glutamine tract determines androgen sensitivity in vivo

人雄激素受体谷氨酰胺链的长度决定了体内雄激素敏感性。

Profiling human androgen receptor mutations reveals treatment effects in a mouse model of prostate cancer

对人类雄激素受体突变进行分析揭示了前列腺癌小鼠模型中的治疗效果