日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dual inhibition of sclerostin and Notum induces synergistic osteoanabolic action in mice

双重抑制硬骨蛋白和Notum可诱导小鼠产生协同的骨合成代谢作用

Choi, Roy B; Hoggatt, April M; Horan, Daniel J; Cunningham, Connor J; Brommage, Robert; Powell, David R; Robling, Alexander G

Skeletal phenotypes in secreted frizzled-related protein 4 gene knockout mice mimic skeletal architectural abnormalities in subjects with Pyle's disease from SFRP4 mutations

分泌型卷曲相关蛋白4基因敲除小鼠的骨骼表型与SFRP4突变引起的派尔氏病患者的骨骼结构异常相似。

Brommage, Robert; Liu, Jeff; Powell, David R

Mice Lacking Gpr75 are Hypophagic and Thin

缺乏Gpr75的小鼠表现出食欲减退和体型偏瘦。

Powell, David R; Doree, Deon D; DaCosta, Christopher M; Platt, Kenneth A; Brommage, Robert; Buhring, Lindsey; Revelli, Jean-Pierre; Shadoan, Melanie K

Medical Nutrition Therapy Access in CKD: A Cross-sectional Survey of Patients and Providers

慢性肾脏病患者营养治疗的可及性:一项针对患者和医护人员的横断面调查

Jimenez, Elizabeth Yakes; Kelley, Kathryn; Schofield, Marsha; Brommage, Deborah; Steiber, Alison; Abram, Jenica K; Kramer, Holly

High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes

对小鼠基因敲除进行高通量筛选,鉴定出已知的和新的高体脂表型

Powell, David R; Revelli, Jean-Pierre; Doree, Deon D; DaCosta, Christopher M; Desai, Urvi; Shadoan, Melanie K; Rodriguez, Lawrence; Mullens, Michael; Yang, Qi M; Ding, Zhi-Ming; Kirkpatrick, Laura L; Vogel, Peter; Zambrowicz, Brian; Sands, Arthur T; Platt, Kenneth A; Hansen, Gwenn M; Brommage, Robert

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density

大规模小鼠突变表型分析揭示了控制骨矿物质密度的新基因

Swan, Anna L; Schütt, Christine; Rozman, Jan; Del Mar Muñiz Moreno, Maria; Brandmaier, Stefan; Simon, Michelle; Leuchtenberger, Stefanie; Griffiths, Mark; Brommage, Robert; Keskivali-Bond, Piia; Grallert, Harald; Werner, Thomas; Teperino, Raffaele; Becker, Lore; Miller, Gregor; Moshiri, Ala; Seavitt, John R; Cissell, Derek D; Meehan, Terrence F; Acar, Elif F; Lelliott, Christopher J; Flenniken, Ann M; Champy, Marie-France; Sorg, Tania; Ayadi, Abdel; Braun, Robert E; Cater, Heather; Dickinson, Mary E; Flicek, Paul; Gallegos, Juan; Ghirardello, Elena J; Heaney, Jason D; Jacquot, Sylvie; Lally, Connor; Logan, John G; Teboul, Lydia; Mason, Jeremy; Spielmann, Nadine; McKerlie, Colin; Murray, Stephen A; Nutter, Lauryl M J; Odfalk, Kristian F; Parkinson, Helen; Prochazka, Jan; Reynolds, Corey L; Selloum, Mohammed; Spoutil, Frantisek; Svenson, Karen L; Vales, Taylor S; Wells, Sara E; White, Jacqueline K; Sedlacek, Radislav; Wurst, Wolfgang; Lloyd, K C Kent; Croucher, Peter I; Fuchs, Helmut; Williams, Graham R; Bassett, J H Duncan; Gailus-Durner, Valerie; Herault, Yann; Mallon, Ann-Marie; Brown, Steve D M; Mayer-Kuckuk, Philipp; Hrabe de Angelis, Martin

Obesity of G2e3 Knockout Mice Suggests That Obesity-Associated Variants Near Human G2E3 Decrease G2E3 Activity

G2E3基因敲除小鼠的肥胖表明,人类G2E3基因附近的肥胖相关变异会降低G2E3的活性。

Powell, David R; Doree, Deon D; DaCosta, Christopher M; Platt, Kenneth A; Hansen, Gwenn M; van Sligtenhorst, Isaac; Ding, Zhi-Ming; Revelli, Jean-Pierre; Brommage, Robert

NOTUM inhibition increases endocortical bone formation and bone strength

NOTUM 抑制可增加皮质内骨形成和骨强度

Robert Brommage, Jeff Liu, Peter Vogel, Faika Mseeh, Andrea Y Thompson, David G Potter, Melanie K Shadoan, Gwenn M Hansen, Sabrina Jeter-Jones, Jie Cui, Dawn Bright, Jennifer P Bardenhagen, Deon D Doree, Sofia Movérare-Skrtic, Karin H Nilsson, Petra Henning, Ulf H Lerner, Claes Ohlsson, Arthur T San

High Fidelity of Mouse Models Mimicking Human Genetic Skeletal Disorders

模拟人类遗传性骨骼疾病的高保真小鼠模型

Brommage, Robert; Ohlsson, Claes

Predicting human disease mutations and identifying drug targets from mouse gene knockout phenotyping campaigns

利用小鼠基因敲除表型分析预测人类疾病突变并识别药物靶点

Brommage, Robert; Powell, David R; Vogel, Peter