日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Lactate and histone H3K18 lactylation are associated with metabolic control of gene expression in the retina.

乳酸和组蛋白 H3K18 乳酸化与视网膜基因表达的代谢控制有关。

期刊:PLoS Genetics
影响因子:3.7
doi:10.1371/journal.pgen.1012100
Gaur Mohita, Brooks Matthew J, Liang Xulong, Jiang Ke, Kumari Anjani, English Milton A, Cifani Paolo, Panepinto Maria C, Nellissery Jacob, Fariss Robert N, Campello Laura, Marchal Claire, Swaroop Anand
代谢
乳酸化
发表日期：2026
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Transcriptional Heterogeneity and Differential Response of Rod Photoreceptor Pathway Uncovered by Single-Cell RNA Sequencing of the Aging Mouse Retina.

通过对衰老小鼠视网膜进行单细胞 RNA 测序，揭示了视杆光感受器通路转录异质性和差异反应

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.70001
Campello Laura, Brooks Matthew J, Fadl Benjamin R, Choi Hyo Sub, Pal Soumitra, Swaroop Anand
细胞生物学
Mouse
发表日期：2025
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Aerobic glycolysis and lactate regulate histone H3K18Lactylation occupancy to fine-tune gene expression in developing and mature retina.

有氧糖酵解和乳酸调节组蛋白 H3K18 乳酸化占位，从而微调发育和成熟视网膜中的基因表达

期刊:
影响因子:
doi:10.1101/2025.04.17.649437
Gaur Mohita, Liang Xulong, Brooks Matthew J, Jiang Ke, Kumari Anjani, English Milton A, Cifani Paolo, Panepinto Maria C, Nellissery Jacob, Fariss Robert N, Campello Laura, Marchal Claire, Swaroop Anand
发育与干细胞
发表日期：2025
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Multiomics analyses reveal early metabolic imbalance and mitochondrial stress in neonatal photoreceptors leading to cell death in Pde6brd1/rd1 mouse model of retinal degeneration

多组学分析揭示了Pde6brd1/rd1视网膜变性小鼠模型中新生儿感光细胞早期代谢失衡和线粒体应激，最终导致细胞死亡。

期刊:Human Molecular Genetics
影响因子:3.2
doi:10.1093/hmg/ddac013
Jiang, Ke; Mondal, Anupam Kumar; Adlakha, Yogita K; Gumerson, Jessica; Aponte, Angel; Gieser, Linn; Kim, Jung-Woong; Boleda, Alexis; Brooks, Matthew J; Nellissery, Jacob; Fox, Donald A; Balaban, Robert; Covian, Raul; Swaroop, Anand
细胞生物学
线粒体
代谢
发表日期：2022
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Genetic Rescue of X-Linked Retinoschisis Mouse (Rs1(-/y)) Retina Induces Quiescence of the Retinal Microglial Inflammatory State Following AAV8-RS1 Gene Transfer and Identifies Gene Networks Underlying Retinal Recovery

通过基因拯救X连锁视网膜劈裂症小鼠（Rs1(-/y)）视网膜，AAV8-RS1基因转移可诱导视网膜小胶质细胞炎症状态的静止，并鉴定视网膜恢复相关的基因网络。

期刊:Human Gene Therapy
影响因子:4
doi:10.1089/hum.2020.213
Vijayasarathy, Camasamudram; Zeng, Yong; Brooks, Matthew J; Fariss, Robert N; Sieving, Paul A
胶质细胞
炎症
炎症/感染
细胞生物学
Mouse
发表日期：2021
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Retinal pigment epithelium transcriptome analysis in chronic smoking reveals a suppressed innate immune response and activation of differentiation pathways

慢性吸烟者视网膜色素上皮转录组分析显示先天免疫反应受到抑制，分化途径被激活。

期刊:Free Radical Biology and Medicine
影响因子:8.2
doi:10.1016/j.freeradbiomed.2020.06.004
Wang, Lei; Kaya, Koray D; Kim, Sujung; Brooks, Matthew J; Wang, Jie; Xin, Ying; Qian, Jiang; Swaroop, Anand; Handa, James T
免疫/内分泌
发表日期：2020
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Improved Retinal Organoid Differentiation by Modulating Signaling Pathways Revealed by Comparative Transcriptome Analyses with Development In Vivo

通过调控信号通路改善视网膜类器官分化：体内发育比较转录组分析揭示

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2019.09.009
Brooks, Matthew J; Chen, Holly Y; Kelley, Ryan A; Mondal, Anupam K; Nagashima, Kunio; De Val, Natalia; Li, Tiansen; Chaitankar, Vijender; Swaroop, Anand
3D/类器官
信号转导
发育与干细胞
发表日期：2019
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Accelerated and Improved Differentiation of Retinal Organoids from Pluripotent Stem Cells in Rotating-Wall Vessel Bioreactors

旋转壁式生物反应器中多能干细胞向视网膜类器官分化的加速和改进

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2017.11.001
DiStefano, Tyler; Chen, Holly Yu; Panebianco, Christopher; Kaya, Koray Dogan; Brooks, Matthew J; Gieser, Linn; Morgan, Nicole Y; Pohida, Tom; Swaroop, Anand
干细胞
发育与干细胞
3D/类器官
细胞生物学
发表日期：2018
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Transcriptome profiling of NIH3T3 cell lines expressing opsin and the P23H opsin mutant identifies candidate drugs for the treatment of retinitis pigmentosa

对表达视蛋白和P23H视蛋白突变体的NIH3T3细胞系进行转录组分析，鉴定出治疗视网膜色素变性的候选药物。

期刊:Pharmacological Research
影响因子:10.5
doi:10.1016/j.phrs.2016.10.031
Chen, Yuanyuan; Brooks, Matthew J; Gieser, Linn; Swaroop, Anand; Palczewski, Krzysztof
细胞生物学
发表日期：2017
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Ancient Regulatory Role of Lysine Acetylation in Central Metabolism

赖氨酸乙酰化在中枢代谢中的古代调节作用

期刊:mBio
影响因子:5.1
doi:10.1128/mBio.01894-17
Ernesto S Nakayasu, Meagan C Burnet, Hanna E Walukiewicz, Christopher S Wilkins, Anil K Shukla, Shelby Brooks, Matthew J Plutz, Brady D Lee, Birgit Schilling, Alan J Wolfe, Susanne Müller, John R Kirby, Christopher V Rao, John R Cort, Samuel H Payne
代谢
发表日期：2017
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