日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel Noncatalytic Substrate-Selective p38α-Specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-Inflammatory Activity

新型非催化底物选择性p38α特异性MAPK抑制剂,具有内皮稳定和抗炎活性

Shah, Nirav G; Tulapurkar, Mohan E; Ramarathnam, Aparna; Brophy, Amanda; Martinez, Ramon 3rd; Hom, Kellie; Hodges, Theresa; Samadani, Ramin; Singh, Ishwar S; MacKerell, Alexander D Jr; Shapiro, Paul; Hasday, Jeffrey D

VMY-1-103, a dansylated analog of purvalanol B, induces caspase-3-dependent apoptosis in LNCaP prostate cancer cells.

VMY-1-103 是 purvalanol B 的丹酰化类似物,可诱导 LNCaP 前列腺癌细胞发生 caspase-3 依赖性凋亡

Ringer Lymor, Sirajuddin Paul, Yenugonda Venkata Mahidhar, Ghosh Anup, Divito Kyle, Trabosh Valerie, Patel Yesha, Brophy Amanda, Grindrod Scott, Lisanti Michael P, Rosenthal Dean, Brown Milton L, Avantaggiati Maria Laura, Rodriguez Olga, Albanese Chris