日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

iPSC-derived myelinoids to study myelin biology of humans

利用iPSC衍生的髓鞘样细胞研究人类髓鞘生物学

James, Owen G; Selvaraj, Bhuvaneish T; Magnani, Dario; Burr, Karen; Connick, Peter; Barton, Samantha K; Vasistha, Navneet A; Hampton, David W; Story, David; Smigiel, Robert; Ploski, Rafal; Brophy, Peter J; Ffrench-Constant, Charles; Lyons, David A; Chandran, Siddharthan

Direct Binding of the Flexible C-Terminal Segment of Periaxin to β4 Integrin Suggests a Molecular Basis for CMT4F

Periaxin 柔性 C 端片段与 β4 整合素的直接结合提示了 CMT4F 的分子基础

Raasakka, Arne; Linxweiler, Helen; Brophy, Peter J; Sherman, Diane L; Kursula, Petri

The Axonal Cytoskeleton and the Assembly of Nodes of Ranvier

轴突细胞骨架与郎飞氏结的组装

Ghosh, Aniket; Sherman, Diane L; Brophy, Peter J

Homozygous mutation in the Neurofascin gene affecting the glial isoform of Neurofascin causes severe neurodevelopment disorder with hypotonia, amimia and areflexia

神经纤维蛋白基因纯合突变影响神经纤维蛋白的胶质亚型,导致严重的神经发育障碍,表现为肌张力低下、无呼吸和反射消失。

Smigiel, Robert; Sherman, Diane L; Rydzanicz, Malgorzata; Walczak, Anna; Mikolajkow, Dorota; Krolak-Olejnik, Barbara; Kosinska, Joanna; Gasperowicz, Piotr; Biernacka, Anna; Stawinski, Piotr; Marciniak, Malgorzata; Andrzejewski, Witalij; Boczar, Maria; Krajewski, Pawel; Sasiadek, Maria M; Brophy, Peter J; Ploski, Rafal

A murine model of Charcot-Marie-Tooth disease 4F reveals a role for the C-terminus of periaxin in the formation and stabilization of Cajal bands.

Charcot-Marie-Tooth 病 4F 的小鼠模型揭示了周轴 C 端在 Cajal 带的形成和稳定中的作用

Sherman Diane L, Brophy Peter J

Assembly of CNS Nodes of Ranvier in Myelinated Nerves Is Promoted by the Axon Cytoskeleton

髓鞘神经中枢神经系统郎飞氏结的组装受轴突细胞骨架的促进

Brivio, Veronica; Faivre-Sarrailh, Catherine; Peles, Elior; Sherman, Diane L; Brophy, Peter J

Loss of protohaem IX farnesyltransferase in mature dentate granule cells impairs short-term facilitation at mossy fibre to CA3 pyramidal cell synapses

成熟齿状颗粒细胞中原血红素IX法尼基转移酶的缺失会损害苔藓纤维到CA3锥体细胞突触的短期易化作用。

Booker, Sam A; Campbell, Graham R; Mysiak, Karolina S; Brophy, Peter J; Kind, Peter C; Mahad, Don J; Wyllie, David J A

Restoration of SMN in Schwann cells reverses myelination defects and improves neuromuscular function in spinal muscular atrophy

雪旺细胞中SMN的恢复可以逆转脊髓性肌萎缩症的髓鞘形成缺陷并改善神经肌肉功能。

Hunter, Gillian; Powis, Rachael A; Jones, Ross A; Groen, Ewout J N; Shorrock, Hannah K; Lane, Fiona M; Zheng, Yinan; Sherman, Diane L; Brophy, Peter J; Gillingwater, Thomas H

Absence of Dystrophin Related Protein-2 disrupts Cajal bands in a patient with Charcot-Marie-Tooth disease.

肌营养不良蛋白相关蛋白-2 的缺失会破坏夏科-马里-图斯病患者的卡哈尔带

Brennan Kathryn M, Bai Yunhong, Pisciotta Chiara, Wang Suola, Feely Shawna M E, Hoegger Mark, Gutmann Laurie, Moore Steven A, Gonzalez Michael, Sherman Diane L, Brophy Peter J, Züchner Stephan, Shy Michael E

Differential stability of PNS and CNS nodal complexes when neuronal neurofascin is lost

当神经元神经连接蛋白丢失时,周围神经系统和中枢神经系统节点复合体的稳定性存在差异。

Desmazieres, Anne; Zonta, Barbara; Zhang, Ao; Wu, Lai-Man N; Sherman, Diane L; Brophy, Peter J