日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

DWORF Gene Therapy Improves Cardiac Calcium Handling and Mitochondrial Function

DWORF基因疗法改善心脏钙处理和线粒体功能

Brito-Estrada, Omar; Kuwabara, Yasuhide; Gibson, Aaron M; Hassel, Keira R; Kamradt, Michael L; Verry, Joseph P; Blair, N Scott; Bround, Michael J; Huo, Jiuzhou; Molkentin, Jeffery D; Makarewich, Catherine A

Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner

Thbs1以TGFβ-Smad2/3-ATF4依赖的方式调节骨骼肌质量。

Davy Vanhoutte ,Tobias G Schips ,Rachel A Minerath ,Jiuzhou Huo ,Naga Swathi Sree Kavuri ,Vikram Prasad ,Suh-Chin Lin ,Michael J Bround ,Michelle A Sargent ,Christopher M Adams ,Jeffery D Molkentin

MCU-independent Ca2+ uptake mediates mitochondrial Ca2+ overload and necrotic cell death in a mouse model of Duchenne muscular dystrophy

MCU 独立的 Ca2+ 摄取介导杜氏肌营养不良症小鼠模型中的线粒体 Ca2+ 超载和坏死性细胞死亡

Michael J Bround, Eaman Abay, Jiuzhou Huo, Julian R Havens, Allen J York, Donald M Bers, Jeffery D Molkentin

ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy

ANT依赖性MPTP是肌营养不良症中坏死性肌纤维死亡的根本原因

Michael J Bround ,Julian R Havens ,Allen J York ,Michelle A Sargent ,Jason Karch ,Jeffery D Molkentin

MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle

MCUb是肌肉中钙依赖性线粒体代谢和底物利用的诱导型调节因子。

Jiuzhou Huo ,Vikram Prasad ,Kelly M Grimes ,Davy Vanhoutte ,N Scott Blair ,Suh-Chin Lin ,Michael J Bround ,Donald M Bers ,Jeffery D Molkentin

MCUb Induction Protects the Heart From Postischemic Remodeling

MCUb诱导可保护心脏免受缺血后重塑的影响

Huo, Jiuzhou; Lu, Shan; Kwong, Jennifer Q; Bround, Michael J; Grimes, Kelly M; Sargent, Michelle A; Brown, Milton E; Davis, Michael E; Bers, Donald M; Molkentin, Jeffery D

A novel class of cardioprotective small-molecule PTP inhibitors

一类新型的具有心脏保护作用的小分子 PTP 抑制剂

Salvatore Antonucci, Moises Di Sante, Justina Sileikyte, Jordan Deveraux, Tyler Bauer, Michael J Bround, Roberta Menabò, Melanie Paillard, Petra Alanova, Michela Carraro, Michel Ovize, Jeffery D Molkentin, Michael Cohen, Michael A Forte, Paolo Bernardi, Fabio Di Lisa, Elizabeth Murphy

A 20/20 view of ANT function in mitochondrial biology and necrotic cell death

从宏观角度看ANT在细胞线粒体生物学和坏死性细胞死亡中的作用

Bround, Michael J; Bers, Donald M; Molkentin, Jeffery D

Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD

通过删除 ANT 家族和 CypD 来抑制线粒体通透性转换

Jason Karch, Michael J Bround, Hadi Khalil, Michelle A Sargent, Nadina Latchman, Naohiro Terada, Pablo M Peixoto, Jeffery D Molkentin

The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle

线粒体钙单向转运体是骨骼肌代谢燃料偏好的基础

Jennifer Q Kwong, Jiuzhou Huo, Michael J Bround, Justin G Boyer, Jennifer A Schwanekamp, Nasab Ghazal, Joshua T Maxwell, Young C Jang, Zaza Khuchua, Kevin Shi, Donald M Bers, Jennifer Davis, Jeffery D Molkentin