Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.
肝脏丙二酰辅酶A合成通过抑制脂肪氧化、丙酮酸羧化和氨基酸可用性来抑制糖异生
期刊:Cell Metabolism
影响因子:30.9
doi:10.1016/j.cmet.2024.02.004
Deja Stanislaw, Fletcher Justin A, Kim Chai-Wan, Kucejova Blanka, Fu Xiaorong, Mizerska Monika, Villegas Morgan, Pudelko-Malik Natalia, Browder Nicholas, Inigo-Vollmer Melissa, Menezes Cameron J, Mishra Prashant, Berglund Eric D, Browning Jeffrey D, Thyfault John P, Young Jamey D, Horton Jay D, Burgess Shawn C
