日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Overactive PDGFRα and PDGFRβ promote distinct yet overlapping phenotypes of skeletal muscle fibrosis and stiffness, with PDGFRβ also driving drastic muscle growth.

PDGFRα 和 PDGFRβ 过度活跃会促进骨骼肌纤维化和僵硬的不同但又相互重叠的表型，其中 PDGFRβ 还会驱动肌肉的剧烈生长。

期刊:
影响因子:
doi:10.64898/2026.01.02.697406
Gimla Mariola, Olszewski Szczepan, Brown Jacob L, Raymond-Pope Christiana, Rigsby Sandra, Peelor Frederick F 3rd, Kwon Hae Ryong, Yao Longbiao, Olson Lorin E, Fuqua Jordan D, Miller Benjamin F
发表日期：2026
文献求助 收藏

Reactive oxygen species in the pathogenesis of sarcopenia

活性氧在肌少症发病机制中的作用

期刊:Free Radical Biology and Medicine
影响因子:8.2
doi:10.1016/j.freeradbiomed.2024.11.046
Xu, Hongyang; Brown, Jacob L; Bhaskaran, Shylesh; Van Remmen, Holly
发表日期：2025
文献求助 收藏

Endothelial IGF- 1R deficiency disrupts microvascular homeostasis, impairing skeletal muscle perfusion and endurance: implications for age-related sarcopenia

内皮细胞IGF-1R缺乏会破坏微血管稳态，损害骨骼肌灌注和耐力：对年龄相关性肌肉减少症的影响

期刊:Geroscience
影响因子:5.4
doi:10.1007/s11357-025-01653-2
Nyul-Toth, Adam; Shanmugarama, Santny; Patai, Roland; Gulej, Rafal; Faakye, Janet; Nagy, Dorina; Nagykaldi, Mark; Kiss, Tamas; Csipo, Tamas; Milan, Madison; Ekambaram, Shoba; Negri, Sharon; Nagaraja, Raghavendra Y; Csiszar, Anna; Brown, Jacob L; Van Remmen, Holly; Ungvari, Anna; Yabluchanskiy, Andriy; Tarantini, Stefano; Ungvari, Zoltan
IGF-1
细胞生物学
内皮细胞
发表日期：2025
文献求助 收藏

Pharmacological reduction of lipid hydroperoxides as a potential modulator of sarcopenia.

药物降低脂质氢过氧化物作为肌少症的潜在调节剂

期刊:Journal of Physiology-London
影响因子:4.4
doi:10.1113/JP287090
Brown Jacob L, Xu Hongyang, Duggan Elizabeth, Rosenfeld Craig S, Van Remmen Holly
发表日期：2025
文献求助 收藏

Neuroprotective treatment with the nitrone compound OKN-007 mitigates age-related muscle weakness in aging mice

用硝酮化合物OKN-007进行神经保护治疗可减轻衰老小鼠的年龄相关性肌肉无力。

期刊:Geroscience
影响因子:5.4
doi:10.1007/s11357-024-01134-y
Xu, Hongyang; Piekarz, Katarzyna M; Brown, Jacob L; Bhaskaran, Shylesh; Smith, Nataliya; Towner, Rheal A; Van Remmen, Holly
衰老
发表日期：2024
文献求助 收藏

Development of skeletal muscle fibrosis in a rodent model of cancer cachexia

啮齿动物癌症恶病质模型中骨骼肌纤维化的发展

期刊:Cell Biochemistry and Function
影响因子:2.7
doi:10.1002/cbf.3797
Washington, Tyrone A; Schrems, Eleanor R; Haynie, Wesley S; Rosa-Caldwell, Megan E; Brown, Jacob L; Saling, Landen; Lim, Seongkyun; Perry, Richard A Jr; Brown, Lemuel A; Lee, David E; Greene, Nicholas P
肿瘤
肿瘤免疫
发表日期：2023
文献求助 收藏

Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia

CuZnSOD基因敲除小鼠肌少症模型中肌肉萎缩的转录和代谢通路分子变化

期刊:Geroscience
影响因子:5.4
doi:10.1007/s11357-020-00189-x
Sataranatarajan, Kavithalakshmi; Pharaoh, Gavin; Brown, Jacob L; Ranjit, Rojina; Piekarz, Katarzyna M; Street, Kaitlyn; Wren, Jonathan D; Georgescu, Constantin; Kinter, Caroline; Kinter, Michael; Freeman, Willard M; Richardson, Arlan; Van Remmen, Holly
信号转导
代谢
发表日期：2020
文献求助 收藏

Transcriptomic analysis of the development of skeletal muscle atrophy in cancer-cachexia in tumor-bearing mice

肿瘤荷瘤小鼠癌症恶病质中骨骼肌萎缩发展的转录组分析

期刊:Physiological Genomics
影响因子:2.5
doi:10.1152/physiolgenomics.00061.2018
Blackwell, Thomas A; Cervenka, Igor; Khatri, Bhuwan; Brown, Jacob L; Rosa-Caldwell, Megan E; Lee, David E; Perry, Richard A Jr; Brown, Lemuel A; Haynie, Wesley S; Wiggs, Michael P; Bottje, Walter G; Washington, Tyrone A; Kong, Byungwhi C; Ruas, Jorge L; Greene, Nicholas P
肿瘤
肿瘤免疫
发表日期：2018
文献求助 收藏

Differential effects of leucine supplementation in young and aged mice at the onset of skeletal muscle regeneration

亮氨酸补充剂对幼鼠和老年小鼠骨骼肌再生初期的不同影响

期刊:Mechanisms of Ageing and Development
影响因子:5.1
doi:10.1016/j.mad.2016.05.007
Perry, Richard A Jr; Brown, Lemuel A; Lee, David E; Brown, Jacob L; Baum, Jamie I; Greene, Nicholas P; Washington, Tyrone A
发表日期：2016
文献求助 收藏