Brubaker Gregory相关文献与解析，生知库 | 链接生命科学的每一步

Bhandari Nilam, Prince Ashutosh, Khan Mariam R, Traughber C Alicia, Neupane Kalash, Lorkowski Shuhui W, Brubaker Gregory, Ertugral Elif G, Kothapalli Chandrasekhar R, Dubyak George R, Smith Jonathan D, Gulshan Kailash

焦亡

发表日期：2025

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Zbp1 promotes atherosclerosis and lesion necrosis in mice.

Zbp1 促进小鼠动脉粥样硬化和病变坏死。

期刊:Atherosclerosis

影响因子:5.7

doi:10.1016/j.atherosclerosis.2025.120542

Han Juying, Opoku Emmanuel, Brubaker Gregory, Smith Jonathan D

Disulfiram reduces atherosclerosis and enhances efferocytosis, autophagy, and atheroprotective gut microbiota in hyperlipidemic mice

双硫仑可减轻高脂血症小鼠的动脉粥样硬化，并增强胞吞作用、自噬作用和抗动脉粥样硬化肠道菌群。

期刊:

影响因子:

doi:10.1101/2023.10.17.562757

Traughber, C Alicia; Timinski, Kara; Prince, Ashutosh; Bhandari, Nilam; Neupane, Kalash; Khan, Mariam R; Opoku, Esther; Opoku, Emmanuel; Brubaker, Gregory; Nageshwar, Kanuri; Ertugral, Elif G; Naggareddy, Prabha; Kothapalli, Chandrasekhar R; Smith, Jonathan D; Gulshan, Kailash

Oxidant resistant human apolipoprotein A-I functions similarly to the unmodified human isoform in delaying atherosclerosis progression and promoting atherosclerosis regression in hyperlipidemic mice

抗氧化人载脂蛋白AI与未修饰的人类同工型功能相似，都能延缓高脂血症小鼠动脉粥样硬化的进展并促进动脉粥样硬化的消退。

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0259751

Opoku, Emmanuel; Berisha, Stela; Brubaker, Gregory; Robinet, Peggy; Smith, Jonathan D

First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

载脂蛋白AI的前八个氨基酸残基介导C端对螺旋束展开及其脂化的调控。

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0221915

Brubaker, Gregory; Lorkowski, Shuhui W; Gulshan, Kailash; Hazen, Stanley L; Gogonea, Valentin; Smith, Jonathan D

信号转导

发表日期：2020

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PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly

PI(4,5)P2 由 ABCA1 转运至细胞表面，在那里介导载脂蛋白 A1 的结合和新生 HDL 的组装。

期刊:Circulation Research

影响因子:16.2

doi:10.1161/CIRCRESAHA.116.308856

Gulshan, Kailash; Brubaker, Gregory; Conger, Heather; Wang, Shuhui; Zhang, Renliang; Hazen, Stanley L; Smith, Jonathan D

ABCA1 mediates unfolding of apolipoprotein AI N terminus on the cell surface before lipidation and release of nascent high-density lipoprotein

ABCA1介导载脂蛋白AI N端在细胞表面的展开，随后发生脂化并释放新生高密度脂蛋白。

期刊:Arteriosclerosis Thrombosis and Vascular Biology

影响因子:7.4

doi:10.1161/ATVBAHA.112.301195

Wang, Shuhui; Gulshan, Kailash; Brubaker, Gregory; Hazen, Stanley L; Smith, Jonathan D

A novel compound inhibits reconstituted high-density lipoprotein assembly and blocks nascent high-density lipoprotein biogenesis downstream of apolipoprotein AI binding to ATP-binding cassette transporter A1-expressing cells

一种新型化合物可抑制重组高密度脂蛋白的组装，并阻断载脂蛋白AI与表达ATP结合盒转运蛋白A1细胞结合下游的新生高密度脂蛋白的生物合成。

期刊:Arteriosclerosis Thrombosis and Vascular Biology

影响因子:7.4

doi:10.1161/ATVBAHA.111.234906

Lyssenko, Nicholas N; Brubaker, Gregory; Smith, Bradley D; Smith, Jonathan D

细胞生物学

发表日期：2011

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Apolipoprotein A-I tryptophan substitution leads to resistance to myeloperoxidase-mediated loss of function

载脂蛋白AI色氨酸取代导致对髓过氧化物酶介导的功能丧失产生抵抗力

期刊:Arteriosclerosis Thrombosis and Vascular Biology

影响因子:7.4

doi:10.1161/ATVBAHA.108.173815

Peng, Dao-Quan; Brubaker, Gregory; Wu, Zhiping; Zheng, Lemin; Willard, Belinda; Kinter, Michael; Hazen, Stanley L; Smith, Jonathan D

发表日期：2008

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Large disk intermediate precedes formation of apolipoprotein A-I-dimyristoylphosphatidylcholine small disks

大盘状中间体先于载脂蛋白AI-二肉豆蔻酰磷脂酰胆碱小盘状结构的形成。

期刊:Biochemistry

影响因子:3

doi:10.1021/bi700079w

Zhu, Keng; Brubaker, Gregory; Smith, Jonathan D

发表日期：2007

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ATP8B1 regulates PIP2 localization and cleavage of pyroptotic executioner Gasdermin D.

ATP8B1 调节 PIP2 定位和焦亡执行者 Gasdermin D 的切割

Zbp1 promotes atherosclerosis and lesion necrosis in mice.

Zbp1 促进小鼠动脉粥样硬化和病变坏死。

Disulfiram reduces atherosclerosis and enhances efferocytosis, autophagy, and atheroprotective gut microbiota in hyperlipidemic mice

双硫仑可减轻高脂血症小鼠的动脉粥样硬化，并增强胞吞作用、自噬作用和抗动脉粥样硬化肠道菌群。

Oxidant resistant human apolipoprotein A-I functions similarly to the unmodified human isoform in delaying atherosclerosis progression and promoting atherosclerosis regression in hyperlipidemic mice

抗氧化人载脂蛋白AI与未修饰的人类同工型功能相似，都能延缓高脂血症小鼠动脉粥样硬化的进展并促进动脉粥样硬化的消退。

First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

载脂蛋白AI的前八个氨基酸残基介导C端对螺旋束展开及其脂化的调控。

PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly

PI(4,5)P2 由 ABCA1 转运至细胞表面，在那里介导载脂蛋白 A1 的结合和新生 HDL 的组装。

ABCA1 mediates unfolding of apolipoprotein AI N terminus on the cell surface before lipidation and release of nascent high-density lipoprotein

ABCA1介导载脂蛋白AI N端在细胞表面的展开，随后发生脂化并释放新生高密度脂蛋白。

A novel compound inhibits reconstituted high-density lipoprotein assembly and blocks nascent high-density lipoprotein biogenesis downstream of apolipoprotein AI binding to ATP-binding cassette transporter A1-expressing cells

一种新型化合物可抑制重组高密度脂蛋白的组装，并阻断载脂蛋白AI与表达ATP结合盒转运蛋白A1细胞结合下游的新生高密度脂蛋白的生物合成。

Apolipoprotein A-I tryptophan substitution leads to resistance to myeloperoxidase-mediated loss of function

载脂蛋白AI色氨酸取代导致对髓过氧化物酶介导的功能丧失产生抵抗力

Large disk intermediate precedes formation of apolipoprotein A-I-dimyristoylphosphatidylcholine small disks

大盘状中间体先于载脂蛋白AI-二肉豆蔻酰磷脂酰胆碱小盘状结构的形成。