Bruce Kimberley D相关文献与解析，生知库

Frietze, Seth; Lunn, Cameron; Oldham, Dean; Boyd, Joseph R; Bubak, Andrew N; Bustillos Saucedo, Amalia; Nagel, Maria A; Restrepo, Diego; Bruce, Kimberley D; Niemeyer, Christy S

细胞生物学

炎症/感染

胶质细胞

发表日期：2026

文献求助收藏

Synergistic reduction in interfacial flexibility of TREM2(R47H) and ApoE4 may underlie AD pathology

TREM2(R47H)和ApoE4界面柔性的协同降低可能是AD病理的基础。

期刊:Alzheimers & Dementia

影响因子:11.1

doi:10.1002/alz.70120

Lietzke, Emma E; Saeb, David; Aldrich, Emma C; Bruce, Kimberley D; Sprenger, Kayla G

TREM2

发表日期：2025

文献求助收藏

Do microglia metabolize fructose in Alzheimer's disease?

阿尔茨海默病患者的小胶质细胞是否代谢果糖？

期刊:Journal of Neuroinflammation

影响因子:10.1

doi:10.1186/s12974-025-03401-x

Sturno, Annalise M; Hassell, James E Jr; Lanaspa, Miguel A; Bruce, Kimberley D

The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids

sTREM2的柔性茎结构域调节其与脑内磷脂的相互作用

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.102269

Saeb, David; Lietzke, Emma E; Fuchs, Daisy I; Aldrich, Emma C; Bruce, Kimberley D; Sprenger, Kayla G

Lipid and lipoprotein metabolism in microglia: Alzheimer's disease mechanisms and interventions

小胶质细胞中的脂质和脂蛋白代谢：阿尔茨海默病机制和干预措施

期刊:Journal of Lipid Research

影响因子:4.1

doi:10.1016/j.jlr.2025.100872

Sprenger, Kayla G; Lietzke, Emma E; Melchior, John T; Bruce, Kimberley D

Obesity-Induced MASLD Is Reversed by Capsaicin via Hepatic TRPV1 Activation.

辣椒素通过激活肝脏TRPV1逆转肥胖引起的MASLD

期刊:Current Issues in Molecular Biology

影响因子:3

doi:10.3390/cimb47080618

Baskaran Padmamalini, Christensen Ryan, Bruce Kimberley D, Eckel Robert H

Proteomic analysis of cerebrospinal fluid from females with multiple sclerosis highlights elevated microglial function and impaired neurogenesis

对多发性硬化症女性患者脑脊液的蛋白质组学分析显示，小胶质细胞功能增强，神经发生受损。

期刊:IBRO Neuroscience Reports

影响因子:2.9

doi:10.1016/j.ibneur.2025.08.020

Oldham, Dean; Saviola, Anthony; Alvarez, Enrique; Bruce, Kimberley D

Lipoprotein lipase requires a flexible lid and stable C-terminal, both maintained by ApoC-II peptide binding

脂蛋白脂肪酶需要一个灵活的盖子和一个稳定的C端，这两者都由ApoC-II肽的结合来维持。

期刊:

影响因子:

doi:10.1101/2025.11.20.689556

Lietzke, Emma E; Rouse, Mary S; Oldham, Dean; Dong, Ziyue; Eckel, Robert H; Sprenger, Kayla G; Bruce, Kimberley D

发表日期：2025

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A validated method for banking mixed glial cultures that yield responsive microglia

一种用于保存可产生反应性小胶质细胞的混合胶质细胞培养物的有效方法

期刊:

影响因子:

doi:10.64898/2025.12.13.693524

Sturno, Annalise M; Hassell, James E Jr; Baker, Katelyn M; Potter, Garrett J; Bruce, Kimberley D

Olfactory and trigeminal routes of HSV-1 CNS infection with regional microglial heterogeneity.

HSV-1 中枢神经系统感染的嗅觉和三叉神经途径，伴有区域性小胶质细胞异质性

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/jvi.00968-24

Niemeyer Christy S, Merle Laetitia, Bubak Andrew N, Baxter B Dnate', Gentile Polese Arianna, Colon-Reyes Katherine, Vang Sandy, Hassell James E Jr, Bruce Kimberley D, Nagel Maria A, Restrepo Diego

神经科学

发表日期：2024

文献求助收藏

Intranasal HSV-1 Infection Drives Region-Specific Interferon-Dominant Microglial Remodeling

鼻内HSV-1感染驱动区域特异性干扰素主导的小胶质细胞重塑

Synergistic reduction in interfacial flexibility of TREM2(R47H) and ApoE4 may underlie AD pathology

TREM2(R47H)和ApoE4界面柔性的协同降低可能是AD病理的基础。

Do microglia metabolize fructose in Alzheimer's disease?

阿尔茨海默病患者的小胶质细胞是否代谢果糖？

The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids

sTREM2的柔性茎结构域调节其与脑内磷脂的相互作用

Lipid and lipoprotein metabolism in microglia: Alzheimer's disease mechanisms and interventions

小胶质细胞中的脂质和脂蛋白代谢：阿尔茨海默病机制和干预措施

Obesity-Induced MASLD Is Reversed by Capsaicin via Hepatic TRPV1 Activation.

辣椒素通过激活肝脏TRPV1逆转肥胖引起的MASLD

Proteomic analysis of cerebrospinal fluid from females with multiple sclerosis highlights elevated microglial function and impaired neurogenesis

对多发性硬化症女性患者脑脊液的蛋白质组学分析显示，小胶质细胞功能增强，神经发生受损。

Lipoprotein lipase requires a flexible lid and stable C-terminal, both maintained by ApoC-II peptide binding

脂蛋白脂肪酶需要一个灵活的盖子和一个稳定的C端，这两者都由ApoC-II肽的结合来维持。

A validated method for banking mixed glial cultures that yield responsive microglia

一种用于保存可产生反应性小胶质细胞的混合胶质细胞培养物的有效方法

Olfactory and trigeminal routes of HSV-1 CNS infection with regional microglial heterogeneity.

HSV-1 中枢神经系统感染的嗅觉和三叉神经途径，伴有区域性小胶质细胞异质性