Synthesis of Guaianolide Analogues with a Tunable α-Methylene-γ-lactam Electrophile and Correlating Bioactivity with Thiol Reactivity
合成具有可调 α-亚甲基-γ-内酰胺亲电试剂的愈创木内酯类似物并将生物活性与硫醇反应性关联起来
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.0c01464
Paul A Jackson, Henry A M Schares, Katherine F M Jones, John C Widen, Daniel P Dempe, Francois Grillet, Matthew E Cuellar, Michael A Walters, Daniel A Harki, Kay M Brummond