日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects.

心腔边界紊乱是心脏异常发育和先天性心脏缺陷的根本原因。

Kathiriya Irfan S, Dominguez Martin H, Rao Kavitha S, Muncie-Vasic Jonathon M, Devine W Patrick, Hu Kevin M, Hota Swetansu K, Garay Bayardo I, Quintero Diego, Goyal Piyush, Matthews Megan N, Thomas Reuben, Sukonnik Tatyana, Miguel-Perez Dario, Winchester Sarah, Brower Emily F, Forjaz André, Wu Pei-Hsun, Wirtz Denis, Kiemen Ashley L, Bruneau Benoit G

Reduced TBX5 dosage undermines developmental control of atrial cardiomyocyte identity in a model of human atrial disease

在人类心房疾病模型中,TBX5剂量降低会破坏心房心肌细胞身份的发育控制。

Kathiriya, Irfan S; Rao, Kavitha S; Clark, Alexander P; Hu, Kevin M; Grant, Zoe L; Matthews, Megan N; Chen, Zhe; Hota, Swetansu K; Saucerman, Jeffrey J; Bruneau, Benoit G

Structural variants in human congenital heart disease disrupt distal genomic regulatory contacts of developmental genes.

人类先天性心脏病中的结构变异会破坏发育基因的远端基因组调控联系。

Lee Jodi, Wu Jingshing, Pittman Maureen, Grant Zoe L, Kuang Shuzhen, Quiat Daniel, Morton Sarah U, Fudenberg Geoff, Traglia Michela, Hayes Kelly A, Kumar Ritu, Bruneau Benoit G, Pollard Katherine S

MEF2C controls segment-specific gene regulatory networks that direct heart tube morphogenesis.

MEF2C 控制着节段特异性基因调控网络,从而指导心脏管的形态发生

Muncie-Vasic Jonathon M, Sinha Tanvi, Clark Alexander P, Brower Emily F, Saucerman Jeffrey J, Black Brian L, Bruneau Benoit G

Modeling SMAD2 Mutations in Induced Pluripotent Stem Cells Provides Insights Into Cardiovascular Disease Pathogenesis.

利用诱导多能干细胞模拟SMAD2突变,有助于深入了解心血管疾病的发病机制

Ward Tarsha, Morton Sarah U, Venturini Gabriela, Tai Warren, Jang Min Young, Gorham Joshua, Delaughter Dan, Wasson Lauren K, Khazal Zahra, Homsy Jason, Gelb Bruce D, Chung Wendy K, Bruneau Benoit G, Brueckner Martina, Tristani-Firouzi Martin, DePalma Steven R, Seidman Christine, Seidman J G

4D light sheet imaging, computational reconstruction, and cell tracking in mouse embryos.

小鼠胚胎的 4D 光片成像、计算重建和细胞追踪

Dominguez Martin H, Muncie-Vasic Jonathon M, Bruneau Benoit G

TBXT dose sensitivity and the decoupling of nascent mesoderm specification from EMT progression in 2D human gastruloids.

TBXT 剂量敏感性以及 2D 人类类原肠胚中新生中胚层分化与 EMT 进程的解耦

Bulger Emily A, Muncie-Vasic Ivana, Libby Ashley R G, McDevitt Todd C, Bruneau Benoit G

Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project

基因组的空间和时间组织:4D核组计划的现状和未来目标

Dekker, Job; Alber, Frank; Aufmkolk, Sarah; Beliveau, Brian J; Bruneau, Benoit G; Belmont, Andrew S; Bintu, Lacramioara; Boettiger, Alistair; Calandrelli, Riccardo; Disteche, Christine M; Gilbert, David M; Gregor, Thomas; Hansen, Anders S; Huang, Bo; Huangfu, Danwei; Kalhor, Reza; Leslie, Christina S; Li, Wenbo; Li, Yun; Ma, Jian; Noble, William S; Park, Peter J; Phillips-Cremins, Jennifer E; Pollard, Katherine S; Rafelski, Susanne M; Ren, Bing; Ruan, Yijun; Shav-Tal, Yaron; Shen, Yin; Shendure, Jay; Shu, Xiaokun; Strambio-De-Castillia, Caterina; Vertii, Anastassiia; Zhang, Huaiying; Zhong, Sheng

Modeling congenital heart disease: lessons from mice, hPSC-based models, and organoids

先天性心脏病建模:来自小鼠、基于hPSC的模型和类器官的经验教训

Rao, Kavitha S; Kameswaran, Vasumathi; Bruneau, Benoit G

Cell Layers: uncovering clustering structure in unsupervised single-cell transcriptomic analysis

细胞层:揭示无监督单细胞转录组分析中的聚类结构

Blair, Andrew P; Hu, Robert K; Farah, Elie N; Chi, Neil C; Pollard, Katherine S; Przytycki, Pawel F; Kathiriya, Irfan S; Bruneau, Benoit G