日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multimodal bHLH-PAS DNA binding controls specificity and drives obesity

多模式 bHLH-PAS DNA 结合控制特异性并驱动肥胖

Bersten, David C; McDougal, Daniel P; Sullivan, Adrienne E; Gerassimou, Alexis; Breen, James; Fitzsimmons, Rebecca L; Muscat, George E O; Pederson, Stephen; Bruning, John B; Fan, Chen-Ming; Thomas, Paul Q; Russell, Darryl L; Peet, Daniel J; Whitelaw, Murray L

Structural basis for substrate-dependent allostery in oxygen activation by a cytochrome P450 enzyme revealed by analysis at different temperatures

通过不同温度下的分析揭示了细胞色素P450酶氧活化过程中底物依赖性变构的结构基础

Podgorski, Matthew N; McDougal, Daniel P; Campbell, Eleanor C; Bruning, John B; Bell, Stephen G

Birch Pollen-Related Food Allergy: Occasionally Severe, Yet Home-Based Oral Food Challenges Are Safe

桦树花粉相关食物过敏:偶有严重病例,但居家口服食物激发试验是安全的。

Kallen, E J J; Bruning, A M J; Blaauw, M N; Knulst, A C; Van Ree, R; Welsing, P M J; Le, T M

Cardiodynamic evaluation of sorfequiline (TBAJ-876): results from a first-in-human study

索非奎林(TBAJ-876)的心脏动力学评估:一项首次人体研究的结果

Darpo, Borje; Nedelman, Jerry; Bruning-Barry, Rebecca; Hickman, Dean; Kleiman, Robert; Lombardi, Antonio; Xue, Hongqi

Characteristics of adverse reactions to kratom and implementation of harm reduction strategies in a sample of ethnobotanical tea bar patrons in Colorado

科罗拉多州一家民族植物茶吧顾客对卡痛的不良反应特征及减害策略实施情况

Piercey, Cianna J; Cameron, Joseph; Ahern, Riley; Packwood, Isabella; Bruning, Carter; Henry, Devin; Ruehrmund, Jesse; Weldon, Katelyn; Smith, Kirsten E; Karoly, Hollis C

Protocol for a phase 2, partially blinded, randomized trial assessing the safety and efficacy of sorfequiline or bedaquiline in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis (NC-009)

一项评估索非喹啉或贝达喹啉联合普瑞托马尼和利奈唑胺治疗新诊断的、药物敏感的、涂片阳性肺结核成年患者的安全性和有效性的 2 期、部分盲法、随机试验方案 (NC-009)

Olugbosi, M; Beumont, M; Lombard, L; Nedelman, J; Timm, J; Black, T; Bruning-Barry, R; Hickman, D; Lombardi, A; Betteridge, M; Egizi, E; Marcopulos, L; Henderson, J; Seidel, S; Foraida, S; Benhayoun, M; Sun, E

A ternary switch model governing ERα ligand binding domain conformation

控制ERα配体结合域构象的三元开关模型

McDougal, Daniel P; Pederick, Jordan L; Novick, Scott J; Jovcevski, Blagojce; Warrender, Annmaree K; Pascal, Bruce D; Griffin, Patrick R; Bruning, John B

Structural determinants of non-covalent PPARγ inverse agonism and their therapeutic implications.

非共价 PPARγ 反向激动作用的结构决定因素及其治疗意义。

Kuo Kuang-Ting, Bdiri Bilel, He Yuanjun, Garcia-Ordonez Ruben D, McDougal Daniel P, Ruiz Claudia, Chang Mi Ra, Cameron Michael D, Bruning John B, Kamenecka Theodore M, Griffin Patrick R

Circulating Extracellular Vesicles as Putative Mediators of Cardiovascular Disease in Paediatric Chronic Kidney Disease

循环细胞外囊泡作为儿童慢性肾脏病心血管疾病的潜在介质

Behrens, Felix; Holle, Johannes; Chen, Chia-Yu; Ginsbach, Laura F; Krause, Benjamin C; Bruning, Ulrike; Kriegel, Fabian L; Kaiser, Toralf; Szijártó, István A; Anandakumar, Harithaa; Lehmann, Katrin; Schumacher, Fabian; Durek, Pawel; Heinrich, Frederik F; Lodka, Dörte; Hoffmann, Carina; Borchardt, André A; Peters, Lisa; Michalick, Laura; Querfeld, Uwe; Bufler, Philip; Luch, Andreas; Kleuser, Burkhard; Kirwan, Jennifer A; Forslund, Sofia K; Thumfahrt, Julia; Müller, Dominik; Wilck, Nicola; Mashreghi, Mir-Farzin; Löber, Ulrike; Bartolomaeus, Hendrik; Kuebler, Wolfgang M; Simmons, Szandor

Nivolumab and Relatlimab for the Treatment of Patients with Unresectable or Metastatic Mismatch Repair-Proficient Colorectal Cancer

纳武利尤单抗和瑞拉利单抗用于治疗不可切除或转移性错配修复功能正常的结直肠癌患者

Christenson, Eric S; Ho, Won Jin; Shu, Daniel; Durham, Jennifer N; Brancati, Madelena; Davis Bruning, Heather; Petrie, Susan; Wang, Hao; Lu, Jiayun; Bever, Katherine M; Laheru, Daniel; de Jesus-Acosta, Ana; Browner, Ilene; Donehower, Ross; Pishvaian, Michael J; Azad, Nilofer; Zhu, Qingfeng; Valentin, Alens; Suresh Babu, Jayalaxmi; Hernandez, Alexei; Apostol, George; Gao, Yiyang; Llosa, Nicolas; Housseau, Franck; Pardoll, Drew; Jaffee, Elizabeth M; Anders, Robert; Le, Dung T