日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development

胸腺丛细胞促进髓质富含 IL-4 并塑造胸腺细胞发育

Corey N Miller, Irina Proekt, Jakob von Moltke, Kristen L Wells, Aparna R Rajpurkar, Haiguang Wang, Kristin Rattay, Imran S Khan, Todd C Metzger, Joshua L Pollack, Adam C Fries, Wint W Lwin, Eric J Wigton, Audrey V Parent, Bruno Kyewski, David J Erle, Kristin A Hogquist, Lars M Steinmetz, Richard M

Conventional and Neo-antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors

型糖尿病患者和健康供体中的循环幼稚 CD8+ T 细胞靶向 β 细胞呈递的常规和新抗原肽

Sergio Gonzalez-Duque, Marie Eliane Azoury, Maikel L Colli, Georgia Afonso, Jean-Valery Turatsinze, Laura Nigi, Ana Ines Lalanne, Guido Sebastiani, Alexia Carré, Sheena Pinto, Slobodan Culina, Noémie Corcos, Marco Bugliani, Piero Marchetti, Mathieu Armanet, Marc Diedisheim, Bruno Kyewski, Lars M Ste

T cells specific for post-translational modifications escape intrathymic tolerance induction

针对翻译后修饰的T细胞能够逃脱胸腺内耐受诱导。

Bruno Raposo ,Patrick Merky ,Christina Lundqvist ,Hisakata Yamada ,Vilma Urbonaviciute ,Colin Niaudet ,Johan Viljanen ,Jan Kihlberg ,Bruno Kyewski ,Olov Ekwall ,Rikard Holmdahl ,Johan Bäcklund

Revisiting the Road Map of Medullary Thymic Epithelial Cell Differentiation

重新审视髓样胸腺上皮细胞分化的路线图

Chloé Michel, Corey N Miller, Rita Küchler, Benedikt Brors, Mark S Anderson, Bruno Kyewski, Sheena Pinto

Myelin oligodendrocyte glycoprotein induces incomplete tolerance of CD4(+) T cells specific for both a myelin and a neuronal self-antigen in mice

髓鞘少突胶质细胞糖蛋白诱导小鼠对髓鞘和神经元自身抗原特异的 CD4(+) T 细胞产生不完全耐受

Liliana E Lucca, Pierre-Paul Axisa, Meryem Aloulou, Corine Perals, Abdulraouf Ramadan, Pierre Rufas, Bruno Kyewski, Jens Derbinski, Nicolas Fazilleau, Lennart T Mars, Roland S Liblau

Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells

单细胞转录组分析揭示髓质胸腺上皮细胞中协调的异位基因表达模式

Philip Brennecke, Alejandro Reyes, Sheena Pinto, Kristin Rattay, Michelle Nguyen, Rita Küchler, Wolfgang Huber, Bruno Kyewski, Lars M Steinmetz

Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes

通过新生儿 Fc 受体进行母胎间前胰岛素转移可预防自身免疫性糖尿病

Slobodan Culina, Nimesh Gupta, Raphael Boisgard, Georgia Afonso, Marie-Claude Gagnerault, Jordan Dimitrov, Thomas Østerbye, Sune Justesen, Sandrine Luce, Mikhaël Attias, Bruno Kyewski, Søren Buus, F Susan Wong, Sebastien Lacroix-Desmazes, Roberto Mallone

An organotypic coculture model supporting proliferation and differentiation of medullary thymic epithelial cells and promiscuous gene expression

支持髓质胸腺上皮细胞增殖分化和混杂基因表达的器官型共培养模型

Sheena Pinto, Katrin Schmidt, Stefanie Egle, Hans-Jürgen Stark, Petra Boukamp, Bruno Kyewski

Overlapping gene coexpression patterns in human medullary thymic epithelial cells generate self-antigen diversity

人类髓质胸腺上皮细胞中重叠基因共表达模式产生自身抗原多样性

Sheena Pinto, Chloé Michel, Hannah Schmidt-Glenewinkel, Nathalie Harder, Karl Rohr, Stefan Wild, Benedikt Brors, Bruno Kyewski

Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters

人类胸腺髓质上皮细胞表达了高度多样化的组织特异性基因,这些基因共定位于染色体簇中

Jörn Gotter, Benedikt Brors, Manfred Hergenhahn, Bruno Kyewski