日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Immunoglobulin heavy-chain status and stromal interactions shape ferroptosis sensitivity in chronic lymphocytic leukemia

免疫球蛋白重链状态和基质相互作用影响慢性淋巴细胞白血病对铁死亡的敏感性

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02535-x
Böttcher, Martin; Reemts, Lea; Hengeveld, Paul J; Böttcher-Loschinski, Romy; Bhuria, Vikas; Lu, Junyan; Materna-Reichelt, Silvia; Das, Durdam; Stojanović Gužvić, Natasa; Bruns, Heiko; Huber, Wolfgang; Zenz, Thorsten; Schanze, Denny; Zenker, Martin; Dietrich, Sascha; Langerak, Anton W; Mougiakakos, Dimitrios
白血病
细胞生物学
铁死亡
免疫/内分泌
发表日期：2026
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Functional differences between CLL- and ALL-derived CAR T cells in a 3D tumor microenvironment highlight CXCR4 and IL-10 as potential modulatory targets.

CLL 和 ALL 来源的 CAR T 细胞在 3D 肿瘤微环境中的功能差异凸显了 CXCR4 和 IL-10 作为潜在的调节靶点。

期刊:Hemasphere
影响因子:14.6
doi:10.1002/hem3.70279
Dingfelder Janin, Aigner Michael, Lindacher Jana, Lukas Pascal, Flamann Cindy, Nusser Gina, Zimmermann Katharina, Schambach Axel, Graw Frederik, Völkl Simon, Bruns Heiko, Krumbholz Manuela, Haibach Martina, Wilke Jochen, Mackensen Andreas, Lutzny-Geier Gloria
细胞生物学
IL-10
CXCR4
肿瘤微环境
发表日期：2025
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Impact of Liver and Kidney Function on Vitamin D3 Metabolism in Female and Male Patients Undergoing Allogeneic Hematopoietic Stem-Cell Transplantation

肝肾功能对接受异基因造血干细胞移植的男女患者维生素D3代谢的影响

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26072866
Weich, Laura; Brummer, Christina; Ghimire, Sakhila; Peter, Katrin; Althammer, Michael; Babl, Nathalie; Voll, Florian; Bruss, Christina; Hoering, Marcus; Wallner, Stefan; Siska, Peter J; Holler, Ernst; Herr, Wolfgang; Bruns, Heiko; Heid, Iris M; Stark, Klaus; Kreutz, Marina; Matos, Carina
细胞生物学
发育与干细胞
干细胞
代谢
发表日期：2025
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Elevated high-density lipoprotein levels following acute graft-versus-host disease onset: a potential link to T-cell dysfunction and increased relapse risk

急性移植物抗宿主病发作后高密度脂蛋白水平升高：可能与T细胞功能障碍和复发风险增加有关

期刊:Clinical & Translational Immunology
影响因子:3.8
doi:10.1002/cti2.70060
Böttcher-Loschinski, Romy; Karl, Franziska; Drettwan, Diana; Wittmann, Johannes; Jacobs, Benedikt; Völkl, Simon; Bruns, Heiko; Mackensen, Andreas; Mougiakakos, Dimitrios
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2025
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Enhanced potency of immunotherapy against B-cell precursor acute lymphoblastic leukemia by combination of an Fc-engineered CD19 antibody and CD47 blockade

通过Fc工程化CD19抗体与CD47阻断剂联合应用，增强针对B细胞前体急性淋巴细胞白血病的免疫疗法效力

期刊:Hemasphere
影响因子:14.6
doi:10.1002/hem3.48
Schewe, Denis M; Vogiatzi, Fotini; Münnich, Ira A; Zeller, Tobias; Windisch, Roland; Wichmann, Christian; Müller, Kristina; Bhat, Hilal; Felix, Elisa; Mougiakakos, Dimitrios; Bruns, Heiko; Lenk, Lennart; Valerius, Thomas; Humpe, Andreas; Peipp, Matthias; Kellner, Christian
B细胞
T细胞
CD47
白血病
细胞生物学
CD19
CD4
免疫/内分泌
发表日期：2024
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Gene network-based and ensemble modeling-based selection of tumor-associated antigens with a predicted low risk of tissue damage for targeted immunotherapy

基于基因网络和集成模型的肿瘤相关抗原筛选，以预测其组织损伤风险较低，用于靶向免疫治疗。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2023-008104
Lischer, Christopher; Eberhardt, Martin; Flamann, Cindy; Berges, Johannes; Güse, Esther; Wessely, Anja; Weich, Adrian; Retzlaff, Jimmy; Dörrie, Jan; Schaft, Niels; Wiesinger, Manuel; März, Johannes; Schuler-Thurner, Beatrice; Knorr, Harald; Gupta, Shailendra; Singh, Krishna Pal; Schuler, Gerold; Heppt, Markus Vincent; Koch, Elias Andreas Thomas; van Kleef, Nadine D; Freen-van Heeren, Julian J; Turksma, Annelies W; Wolkenhauer, Olaf; Hohberger, Bettina; Berking, Carola; Bruns, Heiko; Vera, Julio
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2024
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Blockade of the CD47/SIRPα checkpoint axis potentiates the macrophage-mediated antitumor efficacy of tafasitamab

阻断 CD47/SIRPα 检查点轴可增强 tafasitamab 的巨噬细胞介导的抗肿瘤疗效

期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2023.284795
Biedermann, Alexander; Patra-Kneuer, Maria; Mougiakakos, Dimitrios; Büttner-Herold, Maike; Mangelberger-Eberl, Doris; Berges, Johannes; Kellner, Christian; Altmeyer, Sarah; Bittenbring, Jörg Thomas; Augsberger, Christian; Ilieva-Babinsky, Kristina; Haskamp, Stefan; Beier, Fabian; Lischer, Christopher; Vera, Julio; Lührmann, Anja; Bertz, Simone; Völkl, Simon; Jacobs, Benedikt; Steidl, Stefan; Mackensen, Andreas; Bruns, Heiko
巨噬细胞
肿瘤
T细胞
肿瘤免疫
巨噬细胞
CD47
细胞生物学
CD4
免疫/内分泌
发表日期：2024
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Breaking barriers: NEK2 inhibition shines in multiple myeloma treatment

突破障碍：NEK2抑制剂在多发性骨髓瘤治疗中大放异彩

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2023.101237
Lischer, Christopher; Bruns, Heiko
多发性骨髓瘤
NEK2
骨髓瘤
发表日期：2023
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Accumulation of T-cell-suppressive PD-L1(high) extracellular vesicles is associated with GvHD and might impact GvL efficacy

T细胞抑制性PD-L1(高表达)细胞外囊泡的积累与移植物抗宿主病(GvHD)相关，并可能影响移植物抗白血病(GvL)疗效。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2022-006362
Baur, Rebecca; Karl, Franziska; Böttcher-Loschinski, Romy; Stoll, Andrej; Völkl, Simon; Gießl, Andreas; Flamann, Cindy; Bruns, Heiko; Schlötzer-Schrehardt, Ursula; Böttcher, Martin; Schewe, Denis M; Fischer, Thomas; Jitschin, Regina; Mackensen, Andreas; Mougiakakos, Dimitrios
T细胞
白血病
PD-L1
T细胞
囊泡
细胞生物学
免疫/内分泌
发表日期：2023
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Cellular and humoral immune responses to SARS-CoV-2 vaccination in patients after CD19.CAR T-cell therapy

CD19.CAR T细胞疗法后患者对SARS-CoV-2疫苗的细胞和体液免疫反应

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2022007806
Reimann, Hannah; Kremer, Anita N; Blumenberg, Viktoria; Schmidt, Katja; Aigner, Michael; Jacobs, Benedikt; Eisenhauer, Nina; Kämpf, Alina; Rösler, Wolf; Kharboutli, Soraya; Mougiakakos, Dimitrios; Lang, Vanessa; Lischer, Christopher; Irrgang, Pascal; Leppkes, Moritz; Gonzalez, Julio Vera; Krönke, Gerhard; Kremer, Andreas E; Tenbusch, Matthias; Bruns, Heiko; Harrer, Thomas; Müller, Fabian; Schett, Georg; Mackensen, Andreas; Subklewe, Marion; Völkl, Simon
SARS-CoV-2
T细胞
T细胞
细胞生物学
CD19
免疫/内分泌
发表日期：2023
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