日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Acute and persistent changes in neural oscillatory activity predict development of epilepsy following acute organophosphate intoxication in adult rats

成年大鼠急性有机磷中毒后,神经振荡活动的急性和持续性变化可预测癫痫的发生。

MacMahon, Jeremy A; Andrew, Peter M; Izadi, Ali; Bruun, Donald A; Saito, Naomi H; Tancredi, Daniel J; Brooks-Kayal, Amy; Lein, Pamela J; Gurkoff, Gene G

Spatiotemporal perturbations of the plasminogen activation system in a rat model of acute organophosphate intoxication

急性有机磷中毒大鼠模型中纤溶酶原激活系统的时空扰动

Blackmon, Thomas J; MacMahon, Jeremy A; Bernardino, Pedro N; Hogans, Ryan E; Cheng, Mei-Yun; Vu, Joan; Lee, Ruth Diana; Saito, Naomi H; Grodzki, Ana Cristina; Bruun, Donald A; Wulff, Heike; Woolard, Kevin D; Brooks-Kayal, Amy; Harvey, Danielle J; Gorin, Fredric A; Lein, Pamela J

Shifts in the spatiotemporal profile of inflammatory phenotypes of innate immune cells in the rat brain following acute intoxication with the organophosphate diisopropylfluorophosphate

大鼠脑内固有免疫细胞炎症表型时空分布在急性有机磷酸酯类化合物二异丙基氟磷酸酯中毒后的变化

Andrew, Peter M; MacMahon, Jeremy A; Bernardino, Pedro N; Tsai, Yi-Hua; Hobson, Brad A; Porter, Valerie A; Huddleston, Sydney L; Luo, Audrey S; Bruun, Donald A; Saito, Naomi H; Harvey, Danielle J; Brooks-Kayal, Amy; Chaudhari, Abhijit J; Lein, Pamela J

Cardiovascular responses of adult male Sprague-Dawley rats following acute organophosphate intoxication and post-exposure treatment with midazolam with or without allopregnanolone

成年雄性Sprague-Dawley大鼠急性有机磷中毒后,接受咪达唑仑联合或不联合别孕烯醇酮治疗的心血管反应。

Pan, Shiyue; Bruun, Donald A; Lein, Pamela J; Chen, Chao-Yin

A longitudinal MRI and TSPO PET-based investigation of brain region-specific neuroprotection by diazepam versus midazolam following organophosphate-induced seizures

一项基于纵向MRI和TSPO PET的研究,比较了地西泮和咪达唑仑在有机磷酸酯诱发癫痫后对脑区特异性神经保护作用的疗效

Hobson, Brad A; Rowland, Douglas J; Dou, Yimeng; Saito, Naomi; Harmany, Zachary T; Bruun, Donald A; Harvey, Danielle J; Chaudhari, Abhijit J; Garbow, Joel R; Lein, Pamela J

Quantitative T(2) mapping-based longitudinal assessment of brain injury and therapeutic rescue in the rat following acute organophosphate intoxication

基于定量T(2)映射的大鼠急性有机磷中毒后脑损伤及治疗挽救的纵向评估

Almeida, Alita Jesal D; Hobson, Brad A; Saito, Naomi; Bruun, Donald A; Porter, Valerie A; Harvey, Danielle J; Garbow, Joel R; Chaudhari, Abhijit J; Lein, Pamela J

Time- and region-dependent blood-brain barrier impairment in a rat model of organophosphate-induced status epilepticus

有机磷诱导癫痫持续状态大鼠模型中血脑屏障损伤的时间和区域依赖性

Bernardino, Pedro N; Hobson, Brad A; Huddleston, Sydney L; Andrew, Peter M; MacMahon, Jeremy A; Saito, Naomi H; Porter, Valerie A; Bruun, Donald A; Harvey, Danielle J; Garbow, Joel R; Gelli, Angie; Chaudhari, Abhijit J; Lein, Pamela J

Tolerability and pharmacokinetics of intravenous allopregnanolone with and without midazolam pretreatment in two healthy dogs

在两只健康犬中,静脉注射别孕烯醇酮(有/无咪达唑仑预处理)的耐受性和药代动力学研究

Bruun, Donald A; Ma, Betty; Chen, Yi-Je; Wu, Chun-Yi; Aleman, Monica; Zolkowska, Dorota; Smiley-Jewell, Suzette M; Rogawski, Michael A; Lein, Pamela J

Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus

四亚甲基二磺四胺诱导癫痫持续状态后小鼠脑损伤程度的品系差异

Calsbeek, Jonas J; González, Eduardo A; Boosalis, Casey A; Zolkowska, Dorota; Bruun, Donald A; Rowland, Douglas J; Saito, Naomi H; Harvey, Danielle J; Chaudhari, Abhijit J; Rogawski, Michael A; Garbow, Joel R; Lein, Pamela J

The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity

化学致痉挛剂二异丙基氟磷酸酯 (DFP) 会导致成年雄性大鼠出现持续性神经病理学改变,且该改变与癫痫发作无关。

González, Eduardo A; Rindy, Alexa C; Guignet, Michelle A; Calsbeek, Jonas J; Bruun, Donald A; Dhir, Ashish; Andrew, Peter; Saito, Naomi; Rowland, Douglas J; Harvey, Danielle J; Rogawski, Michael A; Lein, Pamela J