A bioengineered hydrogel system enables targeted and sustained intramyocardial delivery of neuregulin, activating the cardiomyocyte cell cycle and enhancing ventricular function in a murine model of ischemic cardiomyopathy
生物工程水凝胶系统能够实现神经调节蛋白在心肌内的靶向和持续输送,从而激活心肌细胞周期并增强缺血性心肌病小鼠模型中的心室功能
期刊:Circulation-Heart Failure
影响因子:7.8
doi:10.1161/CIRCHEARTFAILURE.113.001273
Jeffrey E Cohen, Brendan P Purcell, John W MacArthur Jr, Anbin Mu, Yasuhiro Shudo, Jay B Patel, Christopher M Brusalis, Alen Trubelja, Alexander S Fairman, Bryan B Edwards, Mollie S Davis, George Hung, William Hiesinger, Pavan Atluri, Kenneth B Margulies, Jason A Burdick, Y Joseph Woo