日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Ethanol and its Nonoxidative Metabolites Promote Acute Liver Injury by Inducing ER Stress, Adipocyte Death, and Lipolysis

乙醇及其非氧化代谢物通过诱导内质网应激、脂肪细胞死亡和脂肪分解促进急性肝损伤

期刊:Cellular and Molecular Gastroenterology and Hepatology
影响因子:7.1
doi:10.1016/j.jcmgh.2022.10.002
Seol Hee Park, Wonhyo Seo, Ming-Jiang Xu, Bryan Mackowiak, Yuhong Lin, Yong He, Yaojie Fu, Seonghwan Hwang, Seung-Jin Kim, Yukun Guan, Dechun Feng, Liqing Yu, Richard Lehner, Suthat Liangpunsakul, Bin Gao
代谢
细胞生物学
肝损伤
其它细胞
发表日期：2023
文献求助 收藏

Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure

严重酒精性肝炎的不同组织病理学表型表明导致肝损伤和衰竭的机制不同

期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI157780
Jing Ma, Adrien Guillot, Zhihong Yang, Bryan Mackowiak, Seonghwan Hwang, Ogyi Park, Brandon J Peiffer, Ali Reza Ahmadi, Luma Melo, Praveen Kusumanchi, Nazmul Huda, Romil Saxena, Yong He, Yukun Guan, Dechun Feng, Pau Sancho-Bru, Mengwei Zang, Andrew MacGregor Cameron, Ramon Bataller, Frank Tacke, Zha
代谢
免疫
肝损伤
肝炎
WB
发表日期：2022
文献求助 收藏

E-Selectin-Dependent Inflammation and Lipolysis in Adipose Tissue Exacerbate Steatosis-to-NASH Progression via S100A8/9

脂肪组织中的 E-选择素依赖性炎症和脂肪分解通过 S100A8/9 加剧脂肪变性到 NASH 的进展

期刊:Cellular and Molecular Gastroenterology and Hepatology
影响因子:7.1
doi:10.1016/j.jcmgh.2021.08.002
Robim M Rodrigues, Yong He, Seonghwan Hwang, Adeline Bertola, Bryan Mackowiak, Yeni Ait Ahmed, Wonhyo Seo, Jing Ma, Xiaolin Wang, Seol Hee Park, Yukun Guan, Yaojie Fu, Tamara Vanhaecke, Dechun Feng, Bin Gao
免疫
Immunology/Inflammation
发表日期：2022
文献求助 收藏

Hepatic CYP2B10 is highly induced by binge ethanol and contributes to acute-on-chronic alcohol-induced liver injury

肝脏 CYP2B10 受酗酒高度诱导，并导致慢性酒精性急性肝损伤

期刊:Alcoholism-Clinical and Experimental Research
影响因子:3
doi:10.1111/acer.14954
Bryan Mackowiak, Mingjiang Xu, Yuhong Lin, Yukun Guan, Wonhyo Seo, Ruixue Ren, Dechun Feng, Jace W Jones, Hongbing Wang, Bin Gao
肝损伤
发表日期：2022
文献求助 收藏

Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress

通过诱导氧化应激抑制突变型 BRAF 表达黑色素瘤细胞的细胞外信号调节激酶 2 相互作用化合物的机制分析

期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.1
doi:10.1124/jpet.120.000266
Ramon Martinez 3rd, Weiliang Huang, Ramin Samadani, Bryan Mackowiak, Garrick Centola, Lijia Chen, Ivie L Conlon, Kellie Hom, Maureen A Kane, Steven Fletcher, Paul Shapiro
信号转导
肿瘤
黑色素瘤
肿瘤细胞
WB
Human
发表日期：2021
文献求助 收藏

CITCO as an Adjuvant Facilitates CHOP-Based Lymphoma Treatment in hCAR-Transgenic Mice

CITCO 作为佐剂促进 hCAR 转基因小鼠的 CHOP 淋巴瘤治疗

期刊:Cells
影响因子:5.1
doi:10.3390/cells9112520
Ritika Kurian, William Hedrich, Bryan Mackowiak, Linhao Li, Hongbing Wang
肿瘤
淋巴瘤
发表日期：2020
文献求助 收藏

High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis

组成型雄烷受体 (CAR) 易位的高内涵分析表明柠檬酸莫沙必利是一种抑制糖异生的 CAR 激动剂

期刊:Biochemical Pharmacology
影响因子:5.3
doi:10.1016/j.bcp.2019.07.013
Bryan Mackowiak, Linhao Li, Caitlin Lynch, Andrew Ziman, Scott Heyward, Menghang Xia, Hongbing Wang
信号转导
发表日期：2019
文献求助 收藏

Identification of Modulators That Activate the Constitutive Androstane Receptor From the Tox21 10K Compound Library

从 Tox21 10K 化合物库中鉴定激活组成型雄烷受体的调节剂

期刊:Toxicological Sciences
影响因子:3.4
doi:10.1093/toxsci/kfy242
Caitlin Lynch, Bryan Mackowiak, Ruili Huang, Linhao Li, Scott Heyward, Srilatha Sakamuru, Hongbing Wang, Menghang Xia
信号转导
发表日期：2019
文献求助 收藏

Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor

苯巴比妥介导激活人类而非小鼠孕烷 X 受体的机制见解

期刊:Molecular Pharmacology
影响因子:3.2
doi:10.1124/mol.119.116616
Linhao Li, Matthew A Welch, Zhihui Li, Bryan Mackowiak, Scott Heyward, Peter W Swaan, Hongbing Wang
Human
信号转导
Mouse
发表日期：2019
文献求助 收藏

Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells

野生型和 CAR 敲除 HepaRG 细胞中人类组成型雄烷受体 (CAR) 转录组的全基因组分析

期刊:Biochemical Pharmacology
影响因子:5.3
doi:10.1016/j.bcp.2015.08.087
Daochuan Li, Bryan Mackowiak, Timothy G Brayman, Michael Mitchell, Lei Zhang, Shiew-Mei Huang, Hongbing Wang
免疫
细胞生物学
其它细胞
发表日期：2015
文献求助 收藏