日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A bacteriophage virus-like particle vaccine against oxycodone elicits high-titer and long-lasting antibodies that sequester drug in the blood

针对羟可酮的噬菌体病毒样颗粒疫苗可引发高滴度和持久的抗体,从而将药物隔离在血液中

Isabella G Romano, Susan B Core, Naomi R Lee, Curtis Mowry, Koen K A Van Rompay, Yumei Huang, Bryce Chackerian, Kathryn M Frietze

An Approach for Antigen-Agnostic Identification of Virus-Like Particle-Displayed Epitopes that Engage Specific Antibody V Gene Regions

一种针对特定抗体 V 基因区域的病毒样颗粒展示表位的抗原不可知鉴定方法

Julianne Peabody, Susan B Core, Larance Ronsard, Daniel Lingwood, David S Peabody, Bryce Chackerian

Virus-like particle (VLP)-based vaccine targeting tau phosphorylated at Ser396/Ser404 (PHF1) site outperforms phosphorylated S199/S202 (AT8) site in reducing tau pathology and restoring cognitive deficits in the rTg4510 mouse model of tauopathy

以 Ser396/Ser404 (PHF1) 位点磷酸化的 tau 为靶点的病毒样颗粒 (VLP) 疫苗在减少 tau 病理和恢复 rTg4510 小鼠 tau 蛋白病模型中的认知缺陷方面优于磷酸化的 S199/S202 (AT8) 位点疫苗

Jonathan Hulse, Nicole Maphis, Julianne Peabody, Bryce Chackerian, Kiran Bhaskar

Minimal Determinants for Lifelong Antiviral Antibody Responses in Mice from a Single Exposure to Virus-like Immunogens at Low Doses

小鼠单次接触低剂量病毒样免疫原后产生终生抗病毒抗体反应的最小决定因素

Wei-Yun Wholey, Alexander R Meyer, Sekou-Tidiane Yoda, Bryce Chackerian, Julie Zikherman, Wei Cheng

A virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in non-human primates

基于病毒样颗粒的双价 PCSK9 疫苗可降低非人类灵长类动物的 LDL 胆固醇水平

Alexandra Fowler, Koen K A Van Rompay, Maureen Sampson, Javier Leo, Jennifer K Watanabe, Jodie L Usachenko, Ramya Immareddy, Debbie M Lovato, John T Schiller, Alan T Remaley, Bryce Chackerian

A method for mapping the linear epitopes targeted by the natural antibody response to Zika virus infection using a VLP platform technology

利用 VLP 平台技术绘制寨卡病毒感染天然抗体反应所针对的线性表位的方法

Alexandra Fowler, Chunyan Ye, Elizabeth C Clarke, Juan M Pascale, David S Peabody, Steven B Bradfute, Kathryn M Frietze, Bryce Chackerian

A Virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in Non-Human Primates

基于病毒样颗粒的二价 PCSK9 疫苗可降低非人类灵长类动物的 LDL 胆固醇水平

Alexandra Fowler, Koen K A Van Rompay, Maureen Sampson, Javier Leo, Jennifer K Watanabe, Jodie L Usachenko, Ramya Immareddy, Debbie M Lovato, John T Schiller, Alan T Remaley, Bryce Chackerian

An epitope-based malaria vaccine targeting the junctional region of circumsporozoite protein

针对环子孢子蛋白连接区的表位疟疾疫苗

Lucie Jelínková, Hugo Jhun, Allison Eaton, Nikolai Petrovsky, Fidel Zavala, Bryce Chackerian

Engineering an Antibody V Gene-Selective Vaccine

构建抗体V基因选择性疫苗

Larance Ronsard ,Ashraf S Yousif ,Julianne Peabody ,Vintus Okonkwo ,Pascal Devant ,Alemu Tekewe Mogus ,Ralston M Barnes ,Daniel Rohrer ,Nils Lonberg ,David Peabody ,Bryce Chackerian ,Daniel Lingwood

Expansion and Refinement of Deep Sequence-Coupled Biopanning Technology for Epitope-Specific Antibody Responses in Human Serum

扩展和改进深度序列偶联生物淘选技术,用于人类血清中表位特异性抗体反应

Nikole L Warner, Alexandria C Linville, Susan B Core, Brechla Moreno, Juan M Pascale, David S Peabody, Bryce Chackerian, Kathryn M Frietze