日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Toward the development of a sporadic model of Alzheimer's disease: comparing pathologies between humanized APP and the familial J20 mouse models

开发阿尔茨海默病散发模型:比较人源化 APP 与家族性 J20 小鼠模型的病理学

Peggy Rentsch #, Kiruthika Ganesan #, Alexander Langdon, Lyndsey M Konen, Bryce Vissel

Modeling sporadic Alzheimer's disease in mice by combining Apolipoprotein E4 risk gene with environmental risk factors

结合载脂蛋白 E4 风险基因与环境风险因素,建立小鼠散发性阿尔茨海默病模型

Kiruthika Ganesan #, Peggy Rentsch #, Alexander Langdon, Luke T Milham, Bryce Vissel

Quantification of AMPA receptor subunits and RNA editing-related proteins in the J20 mouse model of Alzheimer's disease by capillary western blotting

毛细管蛋白质印迹法定量分析阿尔茨海默病 J20 小鼠模型中的 AMPA 受体亚基和 RNA 编辑相关蛋白

Luke T Milham #, Gary P Morris #, Lyndsey M Konen, Peggy Rentsch, Nesli Avgan, Bryce Vissel

The Q/R editing site of AMPA receptor GluA2 subunit acts as an epigenetic switch regulating dendritic spines, neurodegeneration and cognitive deficits in Alzheimer's disease

AMPA受体GluA2亚基的Q/R编辑位点作为一种表观遗传开关,调控阿尔茨海默病中的树突棘、神经退行性变和认知缺陷。

Amanda L Wright # ,Lyndsey M Konen # ,Bruce G Mockett # ,Gary P Morris # ,Anurag Singh # ,Lisseth Estefania Burbano ,Luke Milham ,Monica Hoang ,Raphael Zinn ,Rose Chesworth ,Richard P Tan ,Gordon A Royle ,Ian Clark ,Steven Petrou ,Wickliffe C Abraham ,Bryce Vissel

GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors

GluK2 Q/R 编辑调节海人酸受体信号传导和 AMPA 受体的长期增强

Jithin D Nair, Kevin A Wilkinson, Busra P Yucel, Christophe Mulle, Bryce Vissel, Jack Mellor, Jeremy M Henley

Brain health is independently impaired by E-vaping and high-fat diet

电子烟和高脂肪饮食会损害大脑健康

Hui Chen, Baoming Wang, Gerard Li, Joel R Steele, Sandy Stayte, Bryce Vissel, Yik Lung Chan, Chenju Yi, Sonia Saad, Rita Machaalani, Brian G Oliver

Targeting the cannabinoid receptor CB2 in a mouse model of l-dopa induced dyskinesia

针对左旋多巴诱发运动障碍的小鼠模型中的大麻素受体 CB2

Peggy Rentsch, Sandy Stayte, Timothy Egan, Ian Clark, Bryce Vissel

The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain

海人酸受体拮抗剂 UBP310 可抑制 MPTP 诱导的小鼠中脑退化,但不能抑制 GluK1、GluK2 或 GluK3 亚基的单一缺失

Sandy Stayte, Kathryn J Laloli, Peggy Rentsch, Aimee Lowth, Kong M Li, Russell Pickford, Bryce Vissel

A new mouse line with reduced GluA2 Q/R site RNA editing exhibits loss of dendritic spines, hippocampal CA1-neuron loss, learning and memory impairments and NMDA receptor-independent seizure vulnerability

一种 GluA2 Q/R 位点 RNA 编辑减少的新型小鼠系表现出树突棘丢失、海马 CA1 神经元丢失、学习和记忆障碍以及 NMDA 受体独立的癫痫易感性

Lyndsey M Konen, Amanda L Wright, Gordon A Royle, Gary P Morris, Benjamin K Lau, Patrick W Seow, Raphael Zinn, Luke T Milham, Christopher W Vaughan, Bryce Vissel

Time dependent degeneration of the nigrostriatal tract in mice with 6-OHDA lesioned medial forebrain bundle and the effect of activin A on L-Dopa induced dyskinesia

6-OHDA损伤内侧前脑束的小鼠黑质纹状体束的时间依赖性退化及激活素A对左旋多巴诱发运动障碍的影响

Peggy Rentsch, Sandy Stayte, Gary P Morris, Bryce Vissel