日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer

UXS1 的缺失选择性地消耗嘧啶并诱导 KEAP1 突变型肺癌中的复制应激

Gebru, Melat T; Hoffman, Timothy E; Boudreau, Aaron; Vu, Ngoc; Han, Fei; Wang, Putianqi; Folk, Eddie; Wu, Xiumin; Newton, James; Foster-Duke, Kelly D; Gajda, Jessica; Villa, Sammy; Yang, Nianxin; Sandoval, Celeste M; Grant, Christian; Wildeboer, Samatha E; Buck, Wayne R; Hickson, Jonathan A; Firestone, Ari J; Kort, Michael; Bennett, Bryson D; Shotwell, J Brad; Wilson, Noel S; Stokoe, David

Anti-Cryptosporidium efficacy of BKI-1708, an inhibitor of Cryptosporidium calcium-dependent protein kinase 1

BKI-1708(一种隐孢子虫钙依赖性蛋白激酶1抑制剂)的抗隐孢子虫功效

Choi, Ryan; Hulverson, Matthew A; Schaefer, Deborah A; Betzer, Dana P; Riggs, Michael W; Huang, Wenlin; Sun, Vicky; Whitman, Grant R; McCloskey, Molly C; Marsh, Kennan; Buck, Wayne R; Wagner, David S; Yang, Junhai; Bowman, Andrew P; Ciurlionis, Rita; Ajiboye, Jubilee; Hemphill, Andrew; Sigalapalli, Dilep K; Arnold, Samuel L M; Barrett, Lynn K; Ojo, Kayode K; Fan, Erkang; Van Voorhis, Wesley C

Predicting seizure liability of small molecules using an in vitro multi-electrode array based assay coupled with modeling of brain disposition

利用基于体外多电极阵列的检测方法结合脑内分布模型预测小分子药物的致痫性

Belair, David G; Kohnken, Rebecca; McCloud, Rebecca L; Sandoval, Stephanie; Green, Jonathon; Buck, Wayne R; Polakowski, James S

Evaluation of Extended- and Immediate-Release Buprenorphine Formulations on Pharmacokinetics and Injection Site Lesions in Different Strains and Sex of Mice

不同品系和性别小鼠中缓释和速释丁丙诺啡制剂的药代动力学和注射部位损伤评价

Bolin, Susan; Buck, Wayne R; Sun, Yan; Strasburg, Donna; Ebert, Paige; Stolarik, DeAnne; Wang, Yue-Ting; Bratcher-Petersen, Natalie; Clark, Sarah

Neutralizing RGMa with Elezanumab Promotes Cerebroprotection and Recovery in Rabbit Middle Cerebral Artery Occlusion

使用 Elezanumab 中和 RGMa 可促进兔大脑中动脉闭塞的脑保护和恢复。

Jacobson, Peer B; Mothe, Andrea; Levy, Aharon; Krakovsky, Michael; Hooker, Bradley A; Zhang, Xiaomeng; Mollon, Jennifer; Mordashova, Yulia; Droescher, Mathias; Weiss, Sabine; Barghorn, Stefan; Dreher, Ingeborg; Awwad, Khader; Nimmrich, Volker; Huang, Lili; Fung, Emma; Buck, Wayne R; Pfleeger, Kimberly; Ziemann, Adam; Smith, Elaine; Fox, Gerard B; Tator, Charles H; Gold, Michael

Evaluation of Quantitative Platforms for Single Target Mass Spectrometry Imaging

单靶标质谱成像定量平台评价

Bowman, Andrew P; Sawicki, James; Talaty, Nari N; Buck, Wayne R; Yang, Junhai; Wagner, David S

Identification of VEGF Signaling Inhibition-Induced Glomerular Injury in Rats through Site-Specific Urinary Biomarkers

通过位点特异性尿液生物标志物鉴定大鼠 VEGF 信号抑制诱导的肾小球损伤

Yang, Yi; Kowalkowski, Kenneth; Ciurlionis, Rita; Buck, Wayne R; Glaser, Keith B; Albert, Daniel H; Blomme, Eric A G

Comparison of RNA-Seq and Microarray Gene Expression Platforms for the Toxicogenomic Evaluation of Liver From Short-Term Rat Toxicity Studies

比较RNA-Seq和微阵列基因表达平台在短期大鼠毒性研究中对肝脏毒理基因组学评价的应用

Rao, Mohan S; Van Vleet, Terry R; Ciurlionis, Rita; Buck, Wayne R; Mittelstadt, Scott W; Blomme, Eric A G; Liguori, Michael J

Immunomodulatory effects of tick saliva on dermal cells exposed to Borrelia burgdorferi, the agent of Lyme disease.

蜱唾液对暴露于伯氏疏螺旋体(莱姆病病原体)的真皮细胞的免疫调节作用

Scholl Dorothy C, Embers Monica E, Caskey John R, Kaushal Deepak, Mather Thomas N, Buck Wayne R, Morici Lisa A, Philipp Mario T

Selective extraction and effective separation of galactosylsphingosine (psychosine) and glucosylsphingosine from other glycosphingolipids in pathological tissue samples

从病理组织样本中选择性提取并有效分离半乳糖基鞘氨醇(精神苷脂)和葡萄糖基鞘氨醇与其他糖鞘脂。

Li, Yu-Teh; Li, Su-Chen; Buck, Wayne R; Haskins, Mark E; Wu, Sz-Wei; Khoo, Kay-Hooi; Sidransky, Ellen; Bunnell, Bruce A