日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Large-scale single-molecule analysis of tau proteoforms

tau蛋白异构体的大规模单分子分析

Joly, J; Budamagunta, V; Zhang, Z; Nortman, B; Jouzi, M; Bhatnagar, R; Egertson, J D; Flaster, M E; Grothe, R; Guha, S; Kaneshige, K; McVey, K; Nelson, N; Perera, R T; Tan, S J; Trinh, T; Arnott, D; Lipka, J; Pandya, N J; Rougé, L; Wendorff, T J; Kirkpatrick, D S; Rohou, A; Butler, D C; Lotz, S; Forton, A; Sartori, E R; Schwarz, J E; Brereton, P S; Chen, K; Darcy, M A; Golnabi, H R; Hartley, R; Indermuhl, P F; Inman, C E; Jin, K M; Katsyuk, S; Kota, R; Lowry, B; Menger, J C; Miller, D A; Newman, M R; Ogunyemi, A; Robinson, J K; Steiner, N; Sun, J; Tabakman, S; Wang, L; Wang, Z; Wilcox, S K; Kapp, G T; Patel, S; Temple, S; Bertucci, T; Blanchard, J; Huhmer, A; Sankar, S; Juneau, K; Mallick, P

Senolytic treatment alleviates doxorubicin-induced chemobrain

衰老细胞清除疗法可缓解阿霉素诱发的化疗脑

Vivekananda Budamagunta, Ashok Kumar, Asha Rani, Sahana Manohar Sindhu, Yang Yang, Daohong Zhou, Thomas C Foster

Failure of senolytic treatment to prevent cognitive decline in a female rodent model of aging

在衰老雌性啮齿动物模型中,衰老细胞清除治疗未能阻止认知能力下降。

Rani, Asha; Bean, Linda; Budamagunta, Vivekananda; Kumar, Ashok; Foster, Thomas C

Immune Thrombocytopenic Purpura (ITP) With Ulcerative Colitis (UC)

免疫性血小板减少性紫癜(ITP)伴溃疡性结肠炎(UC)

Mohammed, Sohaib K; Budamagunta, Sanjana; Khan, Waleed A; Khan, Muneeb; Lippmann, Steven

Nitroxyl Hybrids with Curcumin and Stilbene Scaffolds Display Potent Antioxidant Activity, Remodel the Amyloid Beta Oligomer, and Reverse Amyloid Beta-Induced Cytotoxicity

含有姜黄素和二苯乙烯支架的硝酰基杂化物表现出强大的抗氧化活性,重塑淀粉样β低聚物,并逆转淀粉样β诱导的细胞毒性

Madhu S Budamagunta, Hidetoshi Mori, Joshua Silk, Ryan R Slez, Balázs Bognár, Ulises Ruiz Mendiola, Tamás Kálai, Izumi Maezawa, John C Voss

Effect of peripheral cellular senescence on brain aging and cognitive decline

外周细胞衰老对大脑衰老和认知衰退的影响

Vivekananda Budamagunta ,Ashok Kumar ,Asha Rani ,Linda Bean ,Sahana Manohar-Sindhu ,Yang Yang ,Daohong Zhou ,Thomas C Foster

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

将 BCL-XL 和 MCL-1 与 DT2216 和 AZD8055 共同靶向可协同抑制小细胞肺癌生长,且不会在小鼠中引起靶向毒性

Sajid Khan, Patrick Kellish, Nick Connis, Dinesh Thummuri, Janet Wiegand, Peiyi Zhang, Xuan Zhang, Vivekananda Budamagunta, Nan Hua, Yang Yang, Umasankar De, Lingtao Jin, Weizhou Zhang, Guangrong Zheng, Robert Hromas, Christine Hann, Maria Zajac-Kaye, Frederic J Kaye, Daohong Zhou

BCL-X(L) PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRAS(G12C)-mutated cancers

BCL-X(L) PROTAC降解剂DT2216与sotorasib在KRAS(G12C)突变癌症的临床前模型中具有协同作用

Khan, Sajid; Wiegand, Janet; Zhang, Peiyi; Hu, Wanyi; Thummuri, Dinesh; Budamagunta, Vivekananda; Hua, Nan; Jin, Lingtao; Allegra, Carmen J; Kopetz, Scott E; Zajac-Kaye, Maria; Kaye, Frederic J; Zheng, Guangrong; Zhou, Daohong

Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL-Specific Degrader DT2216

使用 BCL-XL 特异性降解剂 DT2216 克服胰腺癌的吉西他滨耐药性

Dinesh Thummuri #, Sajid Khan #, Patrick W Underwood #, Peiyi Zhang, Janet Wiegand, Xuan Zhang, Vivekananda Budamagunta, Amin Sobh, Abderrahmane Tagmount, Alexander Loguinov, Andrea N Riner, Ashwin S Akki, Elizabeth Williamson, Robert Hromas, Christopher D Vulpe, Guangrong Zheng, Jose G Trevino, Dao

Novel Stilbene-Nitroxyl Hybrid Compounds Display Discrete Modulation of Amyloid Beta Toxicity and Structure

新型二苯乙烯-硝酰基杂化化合物表现出对淀粉样β蛋白毒性和结构的离散调节

Silvia Hilt, Ruiwu Liu, Izumi Maezawa, Tatu Rojalin, Hnin H Aung, Madhu Budamagunta, Ryan Slez, Qizhi Gong, Randy P Carney, John C Voss