日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Immune cell clustering identifies a CD163⁺/CSF1R⁺ macrophage and neutrophil-enriched phenotype with distinct biological signatures and poor prognosis in angiosarcoma

免疫细胞聚类分析可识别出一种富含CD163⁺/CSF1R⁺巨噬细胞和中性粒细胞的表型，该表型具有独特的生物学特征，且在血管肉瘤中预后不良。

期刊:Oncoimmunology
影响因子:6.3
doi:10.1080/2162402X.2026.2647487
Simon, Adrian Georg; Grothey, Bastian; Lyu, Su Ir; Stahl, David; Schiffmann, Lars Mortimer; Bruns, Christiane Josephine; Eysel, Peer; Buettner, Reinhard; Ullrich, Roland Tillmann; Quaas, Alexander
巨噬细胞
CD16
CSF1
中性粒细胞
巨噬细胞
CD163
粒细胞
细胞生物学
CSF1R
免疫/内分泌
发表日期：2026
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MET-Driven Resistance to Sotorasib in KRAS G12C-Mutant NSCLC and Response to Combined KRAS and MET Inhibition

KRAS G12C突变型非小细胞肺癌中MET驱动的索托拉西布耐药性及对KRAS和MET联合抑制的反应

期刊:JTO Clinical and Research Reports
影响因子:3.5
doi:10.1016/j.jtocrr.2025.100925
Riedel, Richard; Ruge, Lea; Verheyen, Malte; John, Felix; Scharpenseel, Heather; Nogova, Lucia; Michels, Sebastian; Fischer, Rieke N; Eisert, Anna; Jakob, Carolin; Niesen, Emanuel; Fassunke, Jana; Siemanowski-Hrach, Janna; Heydt, Carina; Bunck, Anne; Siebolts, Udo; Merkelbach-Bruse, Sabine; Buettner, Reinhard; Wolf, Jürgen; Scheffler, Matthias
肺癌
肿瘤
肿瘤免疫
细胞生物学
RAS
MET
发表日期：2026
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Schlafen 11 as a prognostic and potentially predictive biomarker in soft tissue sarcoma: evidence from a real-world cohort

Schlafen 11 作为软组织肉瘤的预后和潜在预测生物标志物：来自真实世界队列的证据

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2026.1792367
Simon, Adrian Georg; Lyu, Su Ir; Stahl, David; Schiffmann, Lars Mortimer; Wenk, Birte; Buettner, Reinhard; Wuerdemann, Nora; Tuchscherer, Armin; Ullrich, Roland Tillmann; Quaas, Alexander
发表日期：2026
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The immune landscape in brain metastasis

脑转移瘤的免疫图谱

期刊:Neuro-Oncology
影响因子:13.4
doi:10.1093/neuonc/noae219
Schreurs, Luca D; Vom Stein, Alexander F; Jünger, Stephanie T; Timmer, Marco; Noh, Ka-Won; Buettner, Reinhard; Kashkar, Hamid; Neuschmelting, Volker; Goldbrunner, Roland; Nguyen, Phuong-Hien
神经科学
免疫/内分泌
发表日期：2025
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Single-cell analysis of Barrett's esophagus and carcinoma reveals cell types conferring risk via genetic predisposition.

对巴雷特食管和癌的单细胞分析揭示了通过遗传易感性赋予风险的细胞类型。

期刊:Cell Genomics
影响因子:9
doi:10.1016/j.xgen.2025.100980
Wenzel Marten C, Dasmeh Pouria, Plum Patrick S, Giel Ann-Sophie, Hoppe Sascha, Franitza Marek, Jonas Christoph, Thieme René, Zhao Yue, Heider Dominik, Palles Claire, Fitzgerald Rebecca Claire, Bruns Christiane J, Buettner Reinhard, Quaas Alexander, Gockel Ines, Maj Carlo, Chon Seung-Hun, Schumacher Johannes, Hillmer Axel M
细胞生物学
肿瘤
肿瘤免疫
单细胞
发表日期：2025
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Exploration of histone protein γ-H2AX as a prognostic factor in soft tissue sarcomas and its association with biological behavior, immune cell environment and survival in leiomyosarcoma.

探索组蛋白 α-H2AX 作为软组织肉瘤的预后因素及其与平滑肌肉瘤的生物学行为、免疫细胞环境和生存的关系

期刊:International Journal of Cancer
影响因子:4.7
doi:10.1002/ijc.35310
Simon Adrian Georg, Lyu Su Ir, Schultheis Anne Maria, Stahl David, Wuerdemann Nora, Walter Sebastian, Hieggelke Lena, Buettner Reinhard, Bruns Christiane Josephine, Eysel Peer, Schiffmann Lars Mortimer, Knipper Karl, Mallmann Peter, Quaas Alexander, Ullrich Roland
细胞生物学
H2AX
发表日期：2025
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The expression of the tight junction protein and therapeutical target Claudin 18.2 is heterogeneously distributed within esophageal and gastric adenocarcinoma

紧密连接蛋白和治疗靶点Claudin 18.2在食管和胃腺癌中的表达呈异质性分布。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-12337-4
Pak, Svetlana; Simon, Adrian Georg; Lyu, Su Ir; Tolkach, Yuri; Alakus, Hakan; Zander, Thomas; Buettner, Reinhard; Bruns, Christiane Josephine; Schroeder, Wolfgang; Quaas, Alexander
肿瘤
肿瘤免疫
发表日期：2025
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Genetic diversity in melanomagenesis: a comprehensive analysis of BRAF, NRAS, KIT and novel mutations across melanoma subtypes

黑色素瘤发生中的遗传多样性：对黑色素瘤亚型中BRAF、NRAS、KIT和新型突变的综合分析

期刊:BMC Cancer
影响因子:3.4
doi:10.1186/s12885-025-15458-1
Göze, Ömer Fahrettin; Buettner, Reinhard; Odenthal, Margarete; Heydt, Carina
黑色素瘤
RAS
BRAF
KIT
发表日期：2025
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Benchmark of screening markers for KEAP1/NFE2L2 mutations and joint analysis with the K1N2-score

KEAP1/NFE2L2 突变筛查标志物的基准测试及与 K1N2 评分的联合分析

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-024-00744-1
Arolt, Christoph; Scheel, Andreas H; Dugan, Margaret; Wild, Robert; Richartz, Vanessa; Holz, Barbara; Brägelmann, Johannes; Wagener-Ryczek, Svenja; Merkelbach-Bruse, Sabine; Wolf, Juergen; Buettner, Reinhard; Catanzariti, Luigi; Scheffler, Matthias; Hillmer, Axel M
KEAP1
发表日期：2024
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Fetal gut cell-like differentiation in esophageal adenocarcinoma defines a rare tumor subtype with therapeutically relevant claudin-6 positivity and SWI/SNF gene alteration

食管腺癌中胎儿肠细胞样分化定义了一种罕见的肿瘤亚型，其具有治疗相关的claudin-6阳性和SWI/SNF基因改变。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-024-64116-2
Kraemer, Max; Zander, Thomas; Alakus, Hakan; Buettner, Reinhard; Lyu, Su Ir; Simon, Adrian Georg; Schroeder, Wolfgang; Bruns, Christiane J; Quaas, Alexander
细胞生物学
肿瘤
肿瘤免疫
发表日期：2024
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