日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Uracil-DNA glycosylase deficiency is associated with repressed tumor cell-intrinsic inflammatory signaling and altered sensitivity to exogenous interferons

尿嘧啶-DNA糖苷酶缺乏与肿瘤细胞内在炎症信号传导受抑制以及对外源性干扰素的敏感性改变有关。

Vendetti, Frank P; Pandya, Pinakin; Sclafani, Carina R; Pathak, Sudipta; Buj, Raquel; Jones, Reyna E; Ivanov, Daniel; Aird, Katherine M; Sobol, Robert W; Bakkenist, Christopher J

Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2A (Low) tumors via increased macrophage phagocytosis

肿瘤微环境中锌的可用性通过增强巨噬细胞的吞噬作用来决定 CDKN2A(低表达)肿瘤中的抗 PD-1 反应。

Buj, Raquel; Cole, Aidan R; Danielson, Jeff; Xu, Jimmy; Hurd, Drew; Kishore, Akash; Kedziora, Katarzyna M; Chen, Jie; Yang, Baixue; Barras, David; Uboveja, Apoorva; Amalric, Amandine; Apiz Saab, Juan J; Wickramasinghe, Jayamanna; Tangudu, Naveen Kumar; Levasseur, Evan; Wang, Hui; Minasyan, Aspram; Dadey, Rebekah E; Sharrow, Allison C; Kunning, Sheryl; Vendetti, Frank P; Rivadeneira, Dayana B; Bakkenist, Christopher J; Bruno, Tullia C; Delgoffe, Greg M; Hempel, Nadine; Snyder, Nathaniel W; Bao, Riyue; Soloff, Adam C; Kirk-Wood, John M; Dangaj Laniti, Denarda; Kossenkov, Andrew V; Muir, Alexander; Das, Jishnu; Davar, Diwakar; Mesaros, Clementina; Aird, Katherine M

The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming.

化疗诱导的衰老相关分泌组通过代谢重编程促进细胞脱落和转移扩散

Cole Aidan R, Buj Raquel, Uboveja Apoorva, Levasseur Evan, Wang Hui, Kedziora Katarzyna M, Chatoff Adam, Huacachino Andrea Andress, Marcinkiewicz Mariola M, Amalric Amandine, Yang Baixue, Tangudu Naveen Kumar, Danielson Jeff, Elwah Amal, White Sierra, Li Danyang, Wallace Callen T, Lazure Felicia, Elishaev Esther, Borho Lauren, Jazwinska Dorota E, Laird Matthew S, Atiya Huda, Bitler Benjamin G, Dangaj Denarda, Coffman Lan G, Tseng George, Oesterreich Steffi, Gomes Ana P, Gurkar Aditi U, Schopfer Francisco J, Modugno Francesmary, Watkins Simon C, Zervantonakis Ioannis K, Stallaert Wayne, Hempel Nadine, Snyder Nathaniel W, Aird Katherine M

Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy

富含脱氧尿苷的胞质DNA拮抗STING依赖的先天免疫反应,并使耐药肿瘤对PD-L1抑制剂治疗敏感。

Pandya, Pinakin; Vendetti, Frank P; El-Ghoubaira, Joseph; Pathak, Sudipta; Deppas, Joshua J; Jones, Reyna; Columbus, Anthony V; Zhang, Yunqi; Ivanov, Daniel; Huang, Ziyu; MacDonald, Kate M; Harding, Shane M; Buj, Raquel; Aird, Katherine M; Beumer, Jan H; Sobol, Robert W; Bakkenist, Christopher J

Loss of p16: A Bouncer of the Immunological Surveillance?

p16 的缺失:免疫监视的门卫?

Leon, Kelly E; Tangudu, Naveen Kumar; Aird, Katherine M; Buj, Raquel

Targeting IDH1 as a Prosenescent Therapy in High-grade Serous Ovarian Cancer

以IDH1为靶点的抗衰老疗法在高级别浆液性卵巢癌中的应用

Dahl, Erika S; Buj, Raquel; Leon, Kelly E; Newell, Jordan M; Imamura, Yuka; Bitler, Benjamin G; Snyder, Nathaniel W; Aird, Katherine M

p16: cycling off the beaten path

第16页:骑行探索人迹罕至的小径

Buj, Raquel; Aird, Katherine M

Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease

脱氧核苷三磷酸代谢在癌症和代谢性疾病中的作用

Buj, Raquel; Aird, Katherine M

Quantification of unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples

未甲基化Alu定量分析(QUAlu):一种评估常规临床样本中整体低甲基化程度的工具

Buj, Raquel; Mallona, Izaskun; Díez-Villanueva, Anna; Barrera, Víctor; Mauricio, Dídac; Puig-Domingo, Manel; Reverter, Jordi L; Matias-Guiu, Xavier; Azuara, Daniel; Ramírez, Jose L; Alonso, Sergio; Rosell, Rafael; Capellà, Gabriel; Perucho, Manuel; Robledo, Mercedes; Peinado, Miguel A; Jordà, Mireia

A plasmid toolkit for cloning chimeric cDNAs encoding customized fusion proteins into any Gateway destination expression vector

用于将编码定制融合蛋白的嵌合 cDNA 克隆到任何 Gateway 目标表达载体中的质粒工具包

Buj, Raquel; Iglesias, Noa; Planas, Anna M; Santalucía, Tomàs