日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In Vivo Determinants of Hepatitis C Virus Adaptation and Escape From Neutralizing Antibody AR5A

丙型肝炎病毒适应和逃避中和抗体AR5A的体内决定因素

Velázquez-Moctezuma, Rodrigo; Burm, Rani; Verhoye, Lieven; Collignon, Laura; Holmbeck, Kenn; Giang, Erick; Law, Mansun; Bukh, Jens; Meuleman, Philip; Prentoe, Jannick

Enzymatic Glucosylation Enhances the Solubility of Niclosamide but Abrogates Its Therapeutic Efficacy

酶促糖基化可提高氯硝柳胺的溶解度,但会降低其治疗效果。

Lax, Brianna M; Escorial García, Martina; Fernandez-Antunez, Carlota; Bukh, Jens; Ramirez, Santseharay; Welner, Ditte Hededam

Development of a Norway rat hepacivirus reporter for high-throughput quantification of neutralizing antibodies

开发用于高通量定量检测中和抗体的挪威鼠肝炎病毒报告基因

Kennedy, Matthew J; Wolfisberg, Raphael; Lundsgaard, Emma A; Thorselius, Caroline E; Collignon, Laura; Nielsen, Louise; Holmbeck, Kenn; Bukh, Jens; Scheel, Troels K H

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.

PIP4K2C 抑制可逆转 SARS-CoV-2 引起的自噬通量受损

Karim Marwah, Mishra Manjari, Lo Chieh-Wen, Saul Sirle, Cagirici Halise Busra, Gourdelier Manon, Ghita Luca, Ojha Amrita, Tran Do Hoang Nhu, Agrawal Aditi, McGraw Connor, East Michael P, Gammeltoft Karen Anbro, Sahoo Malaya Kumar, Mooney Nancie A, Johnson Gary L, Das Soumita, Leyssen Pieter, Neyts Johan, Chiu Winston, Cohen Courtney A, Bukh Jens, Gottwein Judith, Dye John M, Neff Norma, Jackson Peter K, Pinsky Benjamin A, Laitinen Tuomo, Pantsar Tatu, Poso Antti, Zanini Fabio, De Jonghe Steven, Asquith Christopher R M, Einav Shirit

Intranasal recombinant protein subunit vaccine targeting TLR3 induces respiratory tract IgA and CD8 T cell responses and protects against respiratory virus infection

鼻内重组蛋白亚单位疫苗靶向TLR3,可诱导呼吸道IgA和CD8 T细胞反应,并预防呼吸道病毒感染。

Katharina Wørzner ,Signe Tandrup Schmidt ,Julie Zimmermann ,Ahmad Tami ,Charlotta Polacek ,Carlota Fernandez-Antunez ,Katrine Top Hartmann ,Rune Fledelius Jensen ,Julia Sid Hansen ,Kristin Illigen ,Louise Krag Isling ,Gitte Erbs ,Gregers Jungersen ,Ida Rosenkrands ,Anna Offersgaard ,Judith Gottwein ,Kenn Holmbeck ,Henrik Elvang Jensen ,Santseharay Ramirez ,Frank Follmann ,Jens Bukh ,Gabriel Kristian Pedersen

Bispecific antibodies against the hepatitis C virus E1E2 envelope glycoprotein

针对丙型肝炎病毒E1E2包膜糖蛋白的双特异性抗体

Radić, Laura; Offersgaard, Anna; Kadavá, Tereza; Zon, Ian; Capella-Pujol, Joan; Mulder, Fabian; Koekkoek, Sylvie; Spek, Vera; Chumbe, Ana; Bukh, Jens; van Gils, Marit J; Sanders, Rogier W; Yin, Victor C; Heck, Albert J R; Gottwein, Judith M; Sliepen, Kwinten; Schinkel, Janke

SARS-CoV-2 Mpro inhibitor ensitrelvir: asymmetrical cross-resistance with nirmatrelvir and emerging resistance hotspots

SARS-CoV-2 Mpro抑制剂恩西替利韦:与尼尔马替利韦存在不对称交叉耐药性及耐药性热点地区出现

Zhou, Yuyong; Gammeltoft, Karen A; Tjørnelund-Sjursen, Helena D; Ryberg, Line A; Offersgaard, Anna; Czarnota, Anna; Duan, Zhe; Pham, Long V; Fahnøe, Ulrik; Peters, Günther H J; Ramirez, Santseharay; Bukh, Jens; Gottwein, Judith M

T cell receptor usage and epitope specificity amongst CD8(+) and CD4(+) SARS-CoV-2-specific T cells

CD8(+)和CD4(+) SARS-CoV-2特异性T细胞的T细胞受体使用情况和表位特异性

Fahnøe, Ulrik; Feng, Shan; Underwood, Alexander P; Jacobsen, Kivin; Ameri, Amir; Blicher, Thomas H; Sølund, Christina S; Rosenberg, Brad R; Brix, Liselotte; Weis, Nina; Bukh, Jens

Cure of chronic hepatitis C virus infection after DAA treatment only partially restores the functional capacity of exhausted T cell subsets: a systematic review

DAA治疗后慢性丙型肝炎病毒感染的治愈仅能部分恢复耗竭T细胞亚群的功能:一项系统性综述

Apol, Ása Didriksen; Sølund, Christina; Vinten, Caroline; Underwood, Alexander P; Bukh, Jens; Weis, Nina

In vivo and in vitro recombinant systems of a novel variant demonstrate cross-reactive neutralization for the HCV model virus, Norway rat hepacivirus

一种新型变异株的体内和体外重组系统均显示出对HCV模型病毒——挪威鼠肝炎病毒的交叉反应性中和作用。

Thorselius, Caroline E; Kok, Andreas; Wolfisberg, Raphael; Fahnøe, Ulrik; Kennedy, Matthew J; Lundsgaard, Emma A; Mikkelsen, Lotte; Larsen, Mads K; Murthy, Satyapramod; Trivedi, Sheetal; Kapoor, Amit; Scheel, Troels K H; Holmbeck, Kenn; Bukh, Jens