日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants

Ripretinib (DCC-2618) 是一种针对广谱致癌和耐药 KIT 和 PDGFRA 变体的开关控制激酶抑制剂

期刊:Cancer Cell
影响因子:48.8
doi:10.1016/j.ccell.2019.04.006
Bryan D Smith, Michael D Kaufman, Wei-Ping Lu, Anu Gupta, Cynthia B Leary, Scott C Wise, Thomas J Rutkoski, Yu Mi Ahn, Gada Al-Ani, Stacie L Bulfer, Timothy M Caldwell, Lawrence Chun, Carol L Ensinger, Molly M Hood, Arin McKinley, William C Patt, Rodrigo Ruiz-Soto, Ying Su, Hanumaiah Telikepalli, Aj
肿瘤
发表日期：2019
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Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97

AAA+ ATPase p97 苯基吲哚抑制剂的优化

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.8b00372
LaPorte, Matthew G; Burnett, James C; Colombo, Raffaele; Bulfer, Stacie L; Alverez, Celeste; Chou, Tsui-Fen; Neitz, R Jeffrey; Green, Neal; Moore, William J; Yue, Zhizhou; Li, Shan; Arkin, Michelle R; Wipf, Peter; Huryn, Donna M
发表日期：2018
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A threonine turnstile defines a dynamic amphiphilic binding motif in the AAA ATPase p97 allosteric binding site

苏氨酸旋转门定义了 AAA ATPase p97 变构结合位点中的动态两亲结合基序

期刊:Organic & Biomolecular Chemistry
影响因子:2.9
doi:10.1039/c7ob00526a
James C Burnett, Chaemin Lim, Brian D Peyser, Lalith P Samankumara, Marina Kovaliov, Raffaele Colombo, Stacie L Bulfer, Matthew G LaPorte, Ann R Hermone, Connor F McGrath, Michelle R Arkin, Rick Gussio, Donna M Huryn, Peter Wipf
发表日期：2017
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2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

人p97的2.3 Å分辨率冷冻电镜结构及其变构抑制机制

期刊:Science
影响因子:45.8
doi:10.1126/science.aad7974
Banerjee, Soojay; Bartesaghi, Alberto; Merk, Alan; Rao, Prashant; Bulfer, Stacie L; Yan, Yongzhao; Green, Neal; Mroczkowski, Barbara; Neitz, R Jeffrey; Wipf, Peter; Falconieri, Veronica; Deshaies, Raymond J; Milne, Jacqueline L S; Huryn, Donna; Arkin, Michelle; Subramaniam, Sriram
发表日期：2016
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Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway

p97的变构吲哚酰胺抑制剂：泛素通路新型探针的鉴定

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.5b00396
Alverez, Celeste; Bulfer, Stacie L; Chakrasali, Ramappa; Chimenti, Michael S; Deshaies, Raymond J; Green, Neal; Kelly, Mark; LaPorte, Matthew G; Lewis, Taber S; Liang, Mary; Moore, William J; Neitz, R Jeffrey; Peshkov, Vsevolod A; Walters, Michael A; Zhang, Feng; Arkin, Michelle R; Wipf, Peter; Huryn, Donna M
信号转导
发表日期：2016
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p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions

p97疾病突变通过调节核苷酸诱导的构象来改变蛋白质-蛋白质相互作用

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.6b00350
Bulfer, Stacie L; Chou, Tsui-Fen; Arkin, Michelle R
发表日期：2016
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Altered cofactor regulation with disease-associated p97/VCP mutations

疾病相关 p97/VCP 突变导致辅因子调节改变

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.1418820112
Xiaoyi Zhang, Lin Gui, Xiaoyan Zhang, Stacie L Bulfer, Valentina Sanghez, Daniel E Wong, YouJin Lee, Lynn Lehmann, James Siho Lee, Pei-Yin Shih, Henry J Lin, Michelina Iacovino, Conrad C Weihl, Michelle R Arkin, Yanzhuang Wang, Tsui-Fen Chou
信号转导
发表日期：2015
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Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains

p97/VCP ATPase 的特异性抑制和动力学分析表明 D1 和 D2 ATPase 结构域之间存在相互作用

期刊:Journal of Molecular Biology
影响因子:4.7
doi:10.1016/j.jmb.2014.05.022
Tsui-Fen Chou, Stacie L Bulfer, Conrad C Weihl, Kelin Li, Lev G Lis, Michael A Walters, Frank J Schoenen, Henry J Lin, Raymond J Deshaies, Michelle R Arkin
VCP
发表日期：2014
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Crystal structure of homoisocitrate dehydrogenase from Schizosaccharomyces pombe

裂殖酵母同型异柠檬酸脱氢酶的晶体结构

期刊:Proteins-Structure Function and Bioinformatics
影响因子:2.8
doi:10.1002/prot.23231
Bulfer, Stacie L; Hendershot, Jenna M; Trievel, Raymond C
发表日期：2012
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Application of a high-throughput fluorescent acetyltransferase assay to identify inhibitors of homocitrate synthase

应用高通量荧光乙酰转移酶分析法鉴定同型柠檬酸合酶抑制剂

期刊:Analytical Biochemistry
影响因子:2.6
doi:10.1016/j.ab.2010.11.004
Stacie L Bulfer, Thomas J McQuade, Martha J Larsen, Raymond C Trievel
IF
发表日期：2011
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