日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Exploratory analyses of clinical outcomes from the BIIB080 phase 1b study in mild Alzheimer's disease

对BIIB080 1b期研究中轻度阿尔茨海默病患者的临床结果进行探索性分析

Shulman, Melanie; Wu, Shuang; Ziogas, Nick; Edwards, Amanda; Collins, Jessica; Lin, Lin; Tien, Irene; Curiale, Gioacchino; Li, Yumeng; Mummery, Catherine; Lane, Roger; Junge, Candice; Beaver, John; Tian, Ying; Landen, Jaren; Bullain, Szofia; Gallagher, Diana

Erratum to "Results of the first-in-human, randomized, double-blind, placebo-controlled, single- and multiple-ascending dose study of BIIB113 in healthy volunteers" [The Journal of Prevention of Alzheimer's Disease volume 12 (2025) 100302]

对“BIIB113 在健康志愿者中首次人体随机、双盲、安慰剂对照、单次和多次递增剂量研究的结果”的勘误 [阿尔茨海默病预防杂志第 12 卷(2025 年)100302]

Nery, Flavia C; Kaliszczak, Maciej; Suttle, Ben; Jones, Lori; Wu, Shuang; Xie, Jing; Curiale, Gioacchino; Yesilalan, Esin; Hirschhorn, Beth; Wilkes, Denisa; Singh, Dave; Bolin, Martin; Nag, Sangram; Varrone, Andrea; Stenkrona, Per; Morén, Anton Forsberg; Halldin, Christer; Yachnin, Jeffrey; Arnold, H Moore; Bullain, Szofia; Landen, Jaren; Gallagher, Diana; Hering, Heike

Amyloid-Related Imaging Abnormalities (ARIA) in Clinical Trials of Gantenerumab in Early Alzheimer Disease

早期阿尔茨海默病甘特鲁单抗临床试验中的淀粉样蛋白相关影像异常(ARIA)

Salloway, Stephen; Wojtowicz, Jakub; Voyle, Nicola; Lane, Christopher A; Klein, Gregory; Lyons, Marco; Rossomanno, Simona; Mazzo, Francesca; Bullain, Szofia; Barkhof, Frederik; Bittner, Tobias; Schneider, Andres; Grundman, Michael; Aldea, Roxana; Boada, Mercè; Smith, Janice; Doody, Rachelle

Results of the first-in-human, randomized, double-blind, placebo-controlled, single- and multiple-ascending dose study of BIIB113 in healthy volunteers

首次在健康志愿者中进行的 BIIB113 人体随机、双盲、安慰剂对照、单次和多次递增剂量研究结果

Nery, Flavia C; Kaliszczak, Maciej; Suttle, Ben; Jones, Lori; Wu, Shuang; Xie, Jing; Curiale, Gioacchino; Yesilalan, Esin; Hirschhorn, Beth; Wilkes, Denisa; Singh, Dave; Bolin, Martin; Nag, Sangram; Varrone, Andrea; Stenkrona, Per; Morén, Anton Forsberg; Halldin, Christer; Yachnin, Jeffrey; Arnold, H Moore; Bullain, Szofia; Landen, Jaren; Gallagher, Diana; Hering, Heike

Long-Term Safety of Gantenerumab in Participants with Alzheimer's Disease: A Phase III, Double-Blind, and Open-Label Extension Study (Marguerite RoAD)

Gantenerumab 在阿尔茨海默病患者中的长期安全性:一项 III 期、双盲、开放标签扩展研究(Marguerite RoAD)

Neve, Anuja; Das, Bibha; Wojtowicz, Jakub; Huang, Zhiyue; Bullain, Szofia; Watkin, Michelle; Lott, Dominik; Bittner, Tobias; Delmar, Paul; Klein, Gregory; Hofmann, Carsten; Kerchner, Geoffrey A; Smith, Janice; Baudler, Monika; Fontoura, Paulo; Doody, Rachelle S

Validation of 3- and 5-point severity scales to assess ARIA-E

验证3分制和5分制严重程度量表在评估ARIA-E中的应用

Bracoud, Luc; Klein, Gregory; Lyons, Marco; Scelsi, Marzia A; Wojtowicz, Jakub; Bullain, Szofia; Purcell, Derk; Fiebach, Jochen B; Barakos, Jerome; Suhy, Joyce

In silico exploration of amyloid-related imaging abnormalities in the gantenerumab open-label extension trials using a semi-mechanistic model

利用半机制模型对gantenerumab开放标签扩展试验中淀粉样蛋白相关影像异常进行计算机模拟探索

Aldea, Roxana; Grimm, Hans Peter; Gieschke, Ronald; Hofmann, Carsten; Lott, Dominik; Bullain, Szofia; Delmar, Paul; Klein, Gregory; Lyons, Marco; Piazza, Fabrizio; Carare, Roxana O; Mazer, Norman A

Comparing ARIA-E severity scales and effects of treatment management thresholds

比较ARIA-E严重程度分级和治疗管理阈值的影响

Klein, Gregory; Scelsi, Marzia A; Barakos, Jerome; Fiebach, Jochen B; Bracoud, Luc; Suhy, Joyce; Delmar, Paul; Lyons, Marco; Wojtowicz, Jakub; Bullain, Szofia; Barkhof, Frederik; Purcell, Derk

Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma

开发第三代抗 EGFRvIII 嵌合 T 细胞和表达 EGFRvIII 的人工抗原呈递细胞用于胶质瘤的过继细胞治疗

Ayguen Sahin, Carlos Sanchez, Szofia Bullain, Peter Waterman, Ralph Weissleder, Bob S Carter

Age of onset of hypertension and risk of dementia in the oldest-old: The 90+ Study

高血压发病年龄与高龄老人痴呆风险:90岁以上人群研究

Corrada, María M; Hayden, Kathleen M; Paganini-Hill, Annlia; Bullain, Szofia S; DeMoss, Jaime; Aguirre, Colette; Brookmeyer, Ron; Kawas, Claudia H