日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The E3-ome gene-centric compendium reveals the human E3 ligase landscape.

以 E3 连接酶组为中心的基因汇编揭示了人类 E3 连接酶的全貌。

Chua Ngee Kiat, González-Robles Tania J, Reddington Cameron J, Dudley-Fraser Jane, Birkinshaw Richard W, Han Jiru, Solano Ashleigh, Wong Soon Wei, Kochańczyk Tomasz, Peter Joshua J, Nakasone Mark A, Aust Florian, Munro Jacob, Tong Yeh Huei, Iskander Julie, Abeysekera Waruni, Garnham Alex, Huckstep Hannah, Ritchie Matthew E, Wertz Ingrid, Hymowitz Sarah, Kumar Sharad, Conaway Ron C, Privé Gilbert G, Bullock Alex N, Babon Jeffrey J, Klevit Rachel E, Lorenz Sonja, Ciulli Alessio, Fischer Eric S, Thomä Nicolas H, Nowak Radosław P, Schulman Brenda A, Rapé Michael, Rittinger Katrin, Pagan Julia K, Bahlo Melanie, Mackay Joel P, Mace Peter D, Lima Christopher D, Hay Ronald T, Komander David, Lechtenberg Bernhard C, Joazeiro Claudio A P, Pagano Michele, Hofmann Kay, Feltham Rebecca

Global nitrogen enrichment impacts plant diversity more than soil bacterial and fungal diversity: a meta-analysis

全球氮富集对植物多样性的影响大于对土壤细菌和真菌多样性的影响:一项荟萃分析

Song, Yu; Kong, Weibo; Wei, Xiaorong; Reich, Peter B; Qiu, Liping; Peñuelas, Josep; Tedersoo, Leho; Bahram, Mohammad; Bullock, James M; Bobbink, Roland; de Vries, Wim; Jia, Xiaoxu; Wang, Xiang; Gou, Xiaomei; Li, Wei; Hu, Yaxian; Li, Tongchuan; Chen, Zhikun; Zhong, Zekun; Jiao, Jintao; Shao, Mingan; Wei, Gehong

GPR146 in adipose tissue drives adipose-liver crosstalk and promotes hepatic steatosis in mice.

脂肪组织中的 GPR146 驱动脂肪-肝脏相互作用,并促进小鼠肝脏脂肪变性。

Shi Yu, Cheng Kai Yan, Thi Thi Tun, Wang Yifan, Yang Yang, Cao Xiaoyun, Chhay Vanna, Shen Yujia, He Yuchen, Zhao Tianyun, Lim Yan Ting, Deik Amy, Dennis Courtney, Pierce Kerry, Bullock Kevin, Wabitsch Martin, Clish Clary B, Banks Alexander S, Sobota Radoslaw M, Cowan Chad A, Yu Haojie

A precision gene-engineered B cell medicine producing sustained levels of active factor IX for hemophilia B therapy

一种精准基因工程改造的B细胞药物,可产生持续水平的活性凝血因子IX,用于治疗B型血友病。

Liu, Hanlan; Singh, Swati; Mullen, Timothy J; Bullock, Caroline; Keegan, Sean; Patterson, Troy; Thakur, Sakshisingh; Lundberg, Amy; Shenker, Sol; Couto, Ryan; Yadav, Charuta; Dastagir, Shamael; Li, Lily; Bainter, Wayne; Liberzon, Ella; Malloy, Connor R; Lazzarotto, Cicera R; Ohsumi, Toshiro K; Chilakala, Shalini; Chen, Huei-Mei; Kshirsagar, Rashmi; Hohmann, Anja F; Arlauckas, Sean P; Lazorchak, Adam; Scull, Chris; Morgan, Richard A

Phase I/II clinical trial of a melanoma vaccine targeting shared non-mutated antigens and a shared mutated BRAF neoantigen with an agonistic CD40 antibody (CDX-1140) plus TLR3 agonist (poly-ICLC)

针对共同的非突变抗原和共同的突变BRAF新抗原的黑色素瘤疫苗的I/II期临床试验,采用激动性CD40抗体(CDX-1140)和TLR3激动剂(poly-ICLC)

Ninmer, Emily K; Petroni, Gina R; Gastman, Brian R; Gaughan, Elizabeth M; Isaacs, James M; Haden, Kathleen; Kaur, Varinder; Wages, Nolan A; Chianese-Bullock, Kimberly A; Smith, Kelly T; Wright, Paul; Bryant, Jennifer; Dunlap-Brown, Marya; Engel, Jack A; Bekiranov, Stefan; Mauldin, Ileana S; Truong, Thach-Giao; Bullock, Timothy N J; Slingluff, Craig L Jr

Metabolic control of innate immune activation in TET2-mutant clonal hematopoiesis

TET2突变克隆性造血中先天免疫激活的代谢控制

Peter Geon Kim,Christopher B Hergott,Aidan P Miller,Amy Deik,Meaghan Boileau,Kevin Bullock,Kerry A Pierce,Angelina H Choy,Wesley Shin,Marie McConkey,Justin Loke,Birgitta A Ryback,Michael N Trinh,Justine C Rutter,Hong Yue,Hojong Yoon,Paul Park,Shourya S Roy Burman,Matthew G Vander Heiden,Eric S Fischer,Scott A Armstrong,Clary Clish,Benjamin L Ebert

Priorities for change for autistic people across Europe

欧洲自闭症人士亟需变革的优先事项

Binte Mohd Ikhsan, Siti Nurnadhirah; Holt, Rosemary; Ruigrok, Amber; Man, Joyce; Parsons, Tracey; Gibbs, Kathryn; Bullock, Edward; Baranger, Aurélie; Allison, Carrie; Doherty, Mary; Ghosh, Anjuli; Terčon, Jerneja; Van den Bosch, Katrien; Baron-Cohen, Simon

BAG3 modulates clathrin-mediated endocytosis and tau uptake in astrocytes

BAG3调节星形胶质细胞中网格蛋白介导的内吞作用和tau蛋白摄取

Rodwell-Bullock, Joel; Blau, Ella; Ganguly, Archan; Deaton, Carol; Johnson, Gail V W

Fibronectin type III domain-containing protein 5/irisin in extracellular vesicles is reduced in older individuals.

老年人细胞外囊泡中的纤连蛋白 III 型结构域蛋白 5/鸢尾素含量降低。

Hunter Tai R, Lyra E Silva Natalia M, de Freitas Guilherme B, Rody Tayna, Santos Luis E, Zhang Jieming, Bullock Alexis, Tartaglia Maria Carmela, Abraham Sheela, Nicolini Chiara, Nelson Aimee J, Heisz Jennifer J, Fahnestock Margaret, De Felice Fernanda G

The Michael Mason prize: development and feasibility testing of a complex intervention to improve adherence to fracture prevention medicine

迈克尔·梅森奖:开发和可行性测试一项旨在提高骨折预防药物依从性的复杂干预措施

Bullock, Laurna; Tyler, Natasha; Fleming, Jane; Clark, Emma M; Thomas, Simon; Gidlow, Christopher; Iglesias-Urrutia, Cynthia P; Horne, Robert; Bentley, Ida; Hawarden, Ashley; Peel, Nicola; Gregson, Celia L; Ralston, Stuart H; Protheroe, Joanne; Lefroy, Janet; Ryan, Sarah; O'Neill, Terence W; Mallen, Christian; Jinks, Clare; Paskins, Zoe