日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Effect of Canagliflozin Pretreatment on the Efficacy of Insulin Therapy to Rescue Type 1 Diabetes-Related Bone Fragility in Male Mice

卡格列净预处理对胰岛素治疗挽救雄性小鼠1型糖尿病相关骨脆性疗效的影响

Nyman, Jeffry S; Bunn, R Clay; Uppuganti, Sasidhar; Hennen, Elizabeth M; Mishra, Plaban; Ray, Philip D; Mendez, Anthony Garcia; Kalaitzoglou, Evangelia; Fowlkes, John L

A myostatin inhibitory antibody combined with insulin, partially rescues the musculoskeletal phenotype of female insulin-deficient diabetic mice.

肌生长抑制素抑制抗体与胰岛素联合使用,可部分挽救雌性胰岛素缺乏型糖尿病小鼠的肌肉骨骼表型

Bunn R Clay, Adatorwovor Reuben, Ray Philip D, Keeble Alexander R, Fry Christopher S, Uppuganti Sasidhar, Nyman Jeffry S, Fowlkes John L, Kalaitzoglou Evangelia

RASopathies: The musculoskeletal consequences and their etiology and pathogenesis

RAS病:肌肉骨骼后果及其病因和发病机制

Fowlkes, John L; Thrailkill, Kathryn M; Bunn, R Clay

Constitutive activation of MEK1 in osteoprogenitors increases strength of bone despite impairing mineralization

骨祖细胞中MEK1的组成型激活虽然会损害矿化作用,但却能增强骨骼强度。

Fowlkes, John L; Bunn, R Clay; Ray, Philip D; Kalaitzoglou, Evangelia; Uppuganti, Sasidhar; Unal, Mustafa; Nyman, Jeffry S; Thrailkill, Kathryn M

Osteo-promoting effects of insulin-like growth factor I (IGF-I) in a mouse model of type 1 diabetes

胰岛素样生长因子 I (IGF-I) 在 1 型糖尿病小鼠模型中的促骨形成作用

Fowlkes, John L; Nyman, Jeffry S; Bunn, R Clay; Jo, Chanhee; Wahl, Elizabeth C; Liu, Lichu; Cockrell, Gael E; Morris, Lindsey M; Lumpkin, Charles K Jr; Thrailkill, Kathryn M

Increasing duration of type 1 diabetes perturbs the strength-structure relationship and increases brittleness of bone

1型糖尿病病程延长会扰乱骨骼的强度-结构关系,并增加骨骼的脆性。

Nyman, Jeffry S; Even, Jesse L; Jo, Chan-Hee; Herbert, Erik G; Murry, Matthew R; Cockrell, Gael E; Wahl, Elizabeth C; Bunn, R Clay; Lumpkin, Charles K Jr; Fowlkes, John L; Thrailkill, Kathryn M

Dysregulation of the intrarenal vitamin D endocytic pathway in a nephropathy-prone mouse model of type 1 diabetes.

1 型糖尿病肾病易发小鼠模型中肾内维生素 D 内吞途径失调

Fowlkes John L, Bunn R Clay, Cockrell Gael E, Clark Lindsey M, Wahl Elizabeth C, Lumpkin Charles K, Thrailkill Kathryn M

Microalbuminuria in type 1 diabetes is associated with enhanced excretion of the endocytic multiligand receptors megalin and cubilin

型糖尿病患者的微量白蛋白尿与内吞多配体受体巨蛋白和立方蛋白的排泄增加有关。

Thrailkill, Kathryn M; Nimmo, Teresa; Bunn, R Clay; Cockrell, Gael E; Moreau, Cynthia S; Mackintosh, Samuel; Edmondson, Ricky D; Fowlkes, John L

Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues

胰岛素是骨骼合成代谢剂吗?解剖糖尿病患者的骨骼寻找线索

Thrailkill, Kathryn M; Lumpkin, Charles K Jr; Bunn, R Clay; Kemp, Stephen F; Fowlkes, John L