Burdick Ryan C相关文献与解析，生知库 | 链接生命科学的每一步

Rathore, Ujjwal; Dugan, Eli; Thornton, Hunter; Kumar, Vigneshwari Easwar; Dajani, Rama; Burdick, Ryan C; Young, Janet M; Steinhart, Zachary; Lao, Reanna; Delviks-Frankenberry, Krista A; Choi, Wooyoung; Henriques, William S; Echeverria, Ignacia; Dann, Emma; Dureja, Ishaan; Pathak, Nandini; Arce, Maya M; McKetney, Justin; Umhoefer, Jennifer M; Parulekar, Simrun; Schmidt, Ralf; Polacco, Benjamin J; Neidleman, Jason; Montano, Mauricio; Nguyen, Vinh Q; Sali, Andrej; Levy, Jay A; Tenthorey, Jeannette L; Cheng, Yifan; Roan, Nadia R; Swaney, Danielle L; Kaake, Robyn M; Dodgson, Stacie E; Hiatt, Joseph; Pathak, Vinay K; Malik, Harmit S; Krogan, Nevan J; Marson, Alexander

T细胞

HIV

微生物学

Elucidating the mechanism by which HIV-1 nucleocapsid mutations confer resistance to integrase strand transfer inhibitors.

阐明 HIV-1 核衣壳突变赋予整合酶链转移抑制剂耐药性的机制。

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.adz8980

Hikichi Yuta, Burdick Ryan C, Patro Sean C, Ding Si-Yuan, Luke Brian T, Clark Erin D, Ablan Sherimay D, Wu Xiaolin, Pathak Vinay K, Freed Eric O

HIV

发表日期：2025

文献求助收藏

Lenacapavir disrupts HIV-1 core integrity while stabilizing the capsid lattice

利那卡帕韦破坏HIV-1核心完整性，同时稳定衣壳结构

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2420497122

Li, Chenglei; Burdick, Ryan C; Siddiqui, Rokeya; Janaka, Sanath Kumar; Hsia, Ru-Ching; Hu, Wei-Shau; Pathak, Vinay K

Lenacapavir-induced Lattice Hyperstabilization is Central to HIV-1 Capsid Failure at the Nuclear Pore Complex and in the Cytoplasm

来那卡帕韦诱导的晶格过度稳定是导致HIV-1衣壳在核孔复合体和细胞质中失效的关键因素。

期刊:

影响因子:

doi:10.1101/2025.04.18.649524

Hudait, Arpa; Burdick, Ryan C; Bare, Ellie K; Pathak, Vinay K; Voth, Gregory A

Elucidating the Mechanism by Which HIV-1 Nucleocapsid Mutations Confer Resistance to Integrase Strand Transfer Inhibitors.

阐明 HIV-1 核衣壳突变赋予整合酶链转移抑制剂耐药性的机制。

期刊:

影响因子:

doi:10.1101/2025.05.17.654662

Hikichi Yuta, Burdick Ryan C, Patro Sean C, Ding Si-Yuan, Luke Brian T, Clark Erin, Ablan Sherimay D, Wu Xiaolin, Pathak Vinay K, Freed Eric O

HIV

发表日期：2025

文献求助收藏

The central pore of HIV-1 capsomers promotes sustained stability of the viral capsid.

HIV-1 衣壳蛋白的中心孔促进病毒衣壳的持续稳定性

期刊:

影响因子:

doi:10.1101/2025.05.19.654868

Kleinpeter Alex B, Mallery Donna L, Albecka Anna, Burdick Ryan C, Renner Nadine, Klarhof J Ole, Vamos Boglarka, Pathak Vinay K, James Leo C, Freed Eric O

The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores

衣壳晶格与二元NUP153基序相互作用，介导HIV-1核心蛋白进入细胞核。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2202815120

Shen, Qi; Kumari, Sushila; Xu, Chaoyi; Jang, Sooin; Shi, Jiong; Burdick, Ryan C; Levintov, Lev; Xiong, Qiancheng; Wu, Chunxiang; Devarkar, Swapnil C; Tian, Taoran; Tripler, Therese N; Hu, Yingxia; Yuan, Shuai; Temple, Joshua; Feng, Qingzhou; Lusk, C Patrick; Aiken, Christopher; Engelman, Alan N; Perilla, Juan R; Pathak, Vinay K; Lin, Chenxiang; Xiong, Yong

HIV-1 cores retain their integrity until minutes before uncoating in the nucleus

HIV-1核心病毒在细胞核内脱壳前几分钟仍能保持其完整性。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2019467118

Li, Chenglei; Burdick, Ryan C; Nagashima, Kunio; Hu, Wei-Shau; Pathak, Vinay K

HIV-1 uncoats in the nucleus near sites of integration

HIV-1 在细胞核内整合位点附近脱壳。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1920631117

Burdick, Ryan C; Li, Chenglei; Munshi, MohamedHusen; Rawson, Jonathan M O; Nagashima, Kunio; Hu, Wei-Shau; Pathak, Vinay K

Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies

通过结构、生化和功能研究深入了解APOBEC3G对DNA底物的选择

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0195048

Ziegler, Samantha J; Liu, Chang; Landau, Mark; Buzovetsky, Olga; Desimmie, Belete A; Zhao, Qi; Sasaki, Tomoaki; Burdick, Ryan C; Pathak, Vinay K; Anderson, Karen S; Xiong, Yong

Systematic discovery of pro- and anti-HIV host factors in primary human CD4+ T cells

系统性地发现原代人CD4+ T细胞中促HIV和抗HIV宿主因子

Elucidating the mechanism by which HIV-1 nucleocapsid mutations confer resistance to integrase strand transfer inhibitors.

阐明 HIV-1 核衣壳突变赋予整合酶链转移抑制剂耐药性的机制。

Lenacapavir disrupts HIV-1 core integrity while stabilizing the capsid lattice

利那卡帕韦破坏HIV-1核心完整性，同时稳定衣壳结构

Lenacapavir-induced Lattice Hyperstabilization is Central to HIV-1 Capsid Failure at the Nuclear Pore Complex and in the Cytoplasm

来那卡帕韦诱导的晶格过度稳定是导致HIV-1衣壳在核孔复合体和细胞质中失效的关键因素。

Elucidating the Mechanism by Which HIV-1 Nucleocapsid Mutations Confer Resistance to Integrase Strand Transfer Inhibitors.

阐明 HIV-1 核衣壳突变赋予整合酶链转移抑制剂耐药性的机制。

The central pore of HIV-1 capsomers promotes sustained stability of the viral capsid.

HIV-1 衣壳蛋白的中心孔促进病毒衣壳的持续稳定性

The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores

衣壳晶格与二元NUP153基序相互作用，介导HIV-1核心蛋白进入细胞核。

HIV-1 cores retain their integrity until minutes before uncoating in the nucleus

HIV-1核心病毒在细胞核内脱壳前几分钟仍能保持其完整性。

HIV-1 uncoats in the nucleus near sites of integration

HIV-1 在细胞核内整合位点附近脱壳。

Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies

通过结构、生化和功能研究深入了解APOBEC3G对DNA底物的选择