日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A dual-reporter mouse for therapeutic discovery in Angelman syndrome

用于安格曼综合征治疗发现的双报告基因小鼠

Vihma, Hanna; James, Lucas M; Nourie, Hannah C; Smith, Audrey L; Liang, Siyuan; Friar, Carlee A; Vulli, Tasmai; Xing, Lei; Cowley, Dale O; Burette, Alain C; Philpot, Benjamin D

Cell Type-Specific Contributions of UBE3A to Angelman Syndrome Behavioral Phenotypes.

UBE3A 对 Angelman 综合征行为表型的细胞类型特异性贡献。

Ringelberg Nicholas W, Mayfield Renée E, Lord Julia S, Diering Graham H, Burette Alain C, Philpot Benjamin D

Regional analysis of myelin basic protein across postnatal brain development of C57BL/6J mice.

C57BL/6J小鼠出生后脑发育过程中髓鞘碱性蛋白的区域分析

Ozarkar Siddhi S, Patel Ridthi K R, Vulli Tasmai, Friar Carlee A, Burette Alain C, Philpot Benjamin D

Juvenile reinstatement of TCF4 in Pitt-Hopkins syndrome model mice reveals a critical window for genetic intervention

在Pitt-Hopkins综合征模型小鼠中,幼年期TCF4的重新表达揭示了基因干预的关键窗口。

James, Lucas M; Friar, Carlee A; Liang, Siyuan; Gao, Eric B; Burette, Alain C; Philpot, Benjamin D

Comparative profiling of white matter development in the human and mouse brain reveals volumetric deficits and delayed myelination in Angelman syndrome

对人类和小鼠大脑白质发育的比较分析揭示了安格曼综合征患者存在体积不足和髓鞘形成延迟。

Ozarkar, Siddhi S; Patel, Ridthi K-R; Vulli, Tasmai; Smith, Audrey L; Styner, Martin A; Hsu, Li-Ming; Lee, Sung-Ho; Shih, Yen-Yu Ian; Hazlett, Heather C; Shen, Mark D; Burette, Alain C; Philpot, Benjamin D

Identification of an elaborate complex mediating postsynaptic inhibition

鉴定介导突触后抑制的复杂复合物

Uezu, Akiyoshi; Kanak, Daniel J; Bradshaw, Tyler W A; Soderblom, Erik J; Catavero, Christina M; Burette, Alain C; Weinberg, Richard J; Soderling, Scott H

GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility

GABA能神经元特异性Ube3a缺失导致类似Angelman综合征的脑电图异常并增加癫痫易感性

Judson, Matthew C; Wallace, Michael L; Sidorov, Michael S; Burette, Alain C; Gu, Bin; van Woerden, Geeske M; King, Ian F; Han, Ji Eun; Zylka, Mark J; Elgersma, Ype; Weinberg, Richard J; Philpot, Benjamin D

Maternal loss of Ube3a produces an excitatory/inhibitory imbalance through neuron type-specific synaptic defects

母体Ube3a基因缺失会导致神经元类型特异性突触缺陷,从而造成兴奋性/抑制性失衡。

Wallace, Michael L; Burette, Alain C; Weinberg, Richard J; Philpot, Benjamin D

Electron tomographic analysis of synaptic ultrastructure

突触超微结构的电子断层扫描分析

Burette, Alain C; Lesperance, Thomas; Crum, John; Martone, Maryann; Volkmann, Niels; Ellisman, Mark H; Weinberg, Richard J

The sodium-driven chloride/bicarbonate exchanger in presynaptic terminals.

突触前末端的钠驱动氯/碳酸氢盐交换器

Burette Alain C, Weinberg Richard J, Sassani Patrick, Abuladze Natalia, Kao Liyo, Kurtz Ira