日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

THP-1-derived polarized macrophages differ by drug transporter transcriptomics, P-glycoprotein activity and rifampicin uptake kinetics

THP-1来源的极化巨噬细胞在药物转运体转录组学、P-糖蛋白活性和利福平摄取动力学方面存在差异。

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-025-04270-2
Hamburg, Katharina; Bay, Cindy; Burhenne, Jürgen; Weiss, Johanna; Stingl, Julia C; Theile, Dirk
巨噬细胞
巨噬细胞
细胞生物学
免疫/内分泌
发表日期：2026
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Novel paracellular marker based on ᴅ-dipeptide structure for highly sensitive quantification with UPLC-MS/MS for in vitro and in vivo blood-brain barrier permeability analysis

基于D-二肽结构的新型细胞旁路标志物，可通过UPLC-MS/MS进行高灵敏度定量分析，用于体外和体内血脑屏障通透性分析。

期刊:Fluids and Barriers of the Cns
影响因子:6.2
doi:10.1186/s12987-026-00806-5
Bay, Cindy; Mühlberg, Eric; Uhl, Philipp; Stingl, Julia Carolin; Bajraktari-Sylejmani, Gzona; Burhenne, Jürgen; Weiss, Johanna; Sauter, Max
血脑屏障
细胞生物学
神经科学
多发性硬化症
发表日期：2026
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Preclinical drug screen identifies WEE1 inhibitor and vinca alkaloid as a combination treatment concept for Li-Fraumeni syndrome medulloblastoma.

临床前药物筛选发现 WEE1 抑制剂和长春花生物碱可作为李-弗劳梅尼综合征髓母细胞瘤的联合治疗方案。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2025.114564
Kolodziejczak Anna S, Selt Florian, Peterziel Heike, Jamaladdin Nora, Mack Norman, Maaß Kendra, Meulenbroeks Chris, Sigaud Romain, Herold-Mende Christel, El Damaty Ahmed, Burhenne Jürgen, Ohmura Shunya, Holland-Letz Tim, Kutscher Lena M, Ernst Aurélie, Wei Pei-Chi, Grünewald Thomas G P, Oehme Ina, Kool Marcel, Jones David T W, Pajtler Kristian W, Kratz Christian P, Pfister Stefan M, Witt Olaf, Milde Till
细胞生物学
发表日期：2026
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Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

胰腺导管腺癌的奥沙利铂耐药性并非主要由药物摄取减少介导，而是与细胞对细胞毒性威胁的凋亡反应较弱密切相关。

期刊:Oncology Reports
影响因子:3.9
doi:10.3892/or.2025.9027
Röttgen, Hellen; Theurer, Lana; Peccerella, Teresa; Sandu, Ketaki; Weiss, Johanna; Burhenne, Jürgen; Neoptolemos, John P; Köberle, Beate; Theile, Dirk
肿瘤
凋亡
表观遗传
肿瘤免疫
细胞生物学
毒理研究
发表日期：2026
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Ependymoma group-specific blood-brain barrier differences uncovered by a multi-omics approach.

通过多组学方法揭示室管膜瘤组特异性血脑屏障差异。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-47499-2
Sundheimer Julia K, Benzel Julia, Federico Aniello, Volz Stefanie, Knoll Maximilian, Statz Britta, Zheng Tuyu, Kmiecik Szymon W, Burhenne Jürgen, Bajraktari-Sylejmani Gzona, Scheuermann Sophia, King Anke, Müller Torsten, Hübner Jens-Martin, Kalxdorf Mathias, Peterziel Heike, Oehme Ina, Krijgsveld Jeroen, Seitz Christian M, Kool Marcel, Pfister Stefan M, Pajtler Kristian W, Maaß Kendra K
血脑屏障
肿瘤
发表日期：2026
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Correction: Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma

更正：用于局部治疗多发性骨髓瘤溶骨性骨病和微小残留病灶的硼替佐米释放二氧化硅-胶原蛋白干凝胶

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-025-01663-9
Hose, Dirk; Ray, Seemun; Rößler, Sina; Thormann, Ulrich; Schnettler, Reinhard; de Veirman, Kim; Khassawna, Thaqif El; Heiss, Christian; Hild, Anne; Zahner, Daniel; Alagboso, Francisca; Henss, Anja; Beck, Susanne; Emde-Rajaratnam, Martina; Burhenne, Jürgen; Bamberger, Juliane; Menu, Eline; de Bruyne, Elke; Gelinsky, Michael; Kampschulte, Marian; Rohnke, Marcus; Wenisch, Sabine; Vanderkerken, Karin; Hanke, Thomas; Seckinger, Anja; Alt, Volker
多发性骨髓瘤
骨髓瘤
发表日期：2025
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Decreased dihydroartemisinin-piperaquine protection against recurrent malaria associated with Plasmodium falciparum plasmepsin 3 copy number variation in Africa

非洲恶性疟原虫血浆素3拷贝数变异与双氢青蒿素-哌喹对复发性疟疾的保护作用降低有关

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-57726-5
Pernaute-Lau, Leyre; Recker, Mario; Tékété, Mamadou; de Sousa, Tais Nóbrega; Traore, Aliou; Fofana, Bakary; Sanogo, Kassim; Morris, Ulrika; Inoue, Juliana; Ferreira, Pedro E; Diallo, Nouhoum; Burhenne, Jürgen; Sagara, Issaka; Dicko, Alassane; Veiga, Maria I; Haefeli, Walter; Björkman, Anders; Djimde, Abdoulaye A; Borrmann, Steffen; Gil, José Pedro
微生物学
疟疾
发表日期：2025
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Effect of Staggered vs. Simultaneous Co-Administration of Bempedoic Acid on Pharmacokinetics of Pravastatin: Randomized, Cross-Over Clinical Trial in Healthy Volunteers

贝培多酸分次给药与同时给药对普伐他汀药代动力学的影响：一项在健康志愿者中进行的随机、交叉临床试验

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17010060
Stoll, Felicitas; Amato, Salvatore; Sauter, Max; Burhenne, Jürgen; Weiss, Johanna; Haefeli, Walter E; Blank, Antje
发表日期：2025
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Phase 2 Randomised Study of Bulevirtide as Monotherapy or Combined With Peg-IFNα-2a as Treatment for Chronic Hepatitis Delta

布列韦肽单药治疗或联合聚乙二醇干扰素α-2a治疗慢性丁型肝炎的II期随机研究

期刊:Liver International
影响因子:5.2
doi:10.1111/liv.70008
Lampertico, Pietro; Bogomolov, Pavel O; Chulanov, Vladimir; Stepanova, Tatiana; Morozov, Viacheslav; Allweiss, Lena; Dandri, Maura; Burhenne, Jürgen; Blank, Antje; Ciesek, Sandra; Elsner, Carina; Dittmer, Ulf; An, Qi; Manuilov, Dmitry; Da, Ben L; Flaherty, John F; Urban, Stephan; Wedemeyer, Heiner
肝炎
发表日期：2025
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In vivo effects of bempedoic acid on microdosed CYP probe drugs

贝培多酸对微剂量CYP探针药物的体内影响

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1544956
Stoll, Felicitas; Amato, Salvatore; Burhenne, Jürgen; Blank, Antje
发表日期：2025
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