日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Regulation of sodium/calcium homeostasis by BacNa(v) gene therapy rescues cardiac dysfunction in chronic heart failure

通过BacNa(v)基因疗法调节钠/钙稳态可改善慢性心力衰竭患者的心脏功能障碍

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.ady4551
Wu, Tianyu; Li, Yongwu; Perelli, Robin M; Siu, Yiu Yan; Tornatore, Anna; Nataren, Josue; Jiang, Xixian; DeLuca, Sophia; Bers, Donald M; Henriquez, Craig; Landstrom, Andrew P; Bursac, Nenad
心力衰竭
心血管
发表日期：2026
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Experimental Platform for Screening and Validation of BacNa(v) Gene Therapy Candidates

用于筛选和验证BacNa(v)基因治疗候选药物的实验平台

期刊:Circulation-Arrhythmia and Electrophysiology
影响因子:9.8
doi:10.1161/CIRCEP.125.014425
Wu, Tianyu; Nguyen, Hung X; Siu, Yiu Yan; Li, Yongwu; Bursac, Nenad
基因治疗
发表日期：2026
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D801N in ATP1A3-encoded Na/K-ATPase alpha 3 causes cardiac arrhythmogenesis through sodium-calcium exchanger-mediated calcium overload

ATP1A3编码的Na/K-ATPase α3中的D801N突变通过钠钙交换器介导的钙超载导致心律失常。

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.197721
Bidzimou, Minu-Tshyeto K; Muralidharan, Padmapriya; Zhang, Zhushan; Raza, Danyal; Needs, Daniel; Sun, Bo; Perelli, Robin M; Moya-Mendez, Mary E; Manivannan, P K Rakesh; Hunanyan, Arsen S; Helfer, Abbigail; Simmons, Christine Q; George, Alfred L Jr; Bers, Donald M; Bursac, Nenad; Mikati, Mohamad A; Landstrom, Andrew P
发表日期：2026
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Crossbow Bioreactors for Studying the Effects of Time-Varying Mechanical Preload and Afterload on Engineered Cardiac Tissues

用于研究时变机械预负荷和后负荷对工程化心脏组织影响的弩式生物反应器

期刊:Advanced Functional Materials
影响因子:19
doi:10.1002/adfm.202519601
Helfer, Abbigail; Strash, Nicholas; Patsy, Marisa; Bursac, Nenad
发表日期：2025
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BacNa(v) Gene Therapy Improves Function of Infarcted Engineered Human Myocardium and NHPs

BacNa(v)基因疗法改善梗死工程化人类心肌和非人灵长类动物的功能

期刊:Circulation Research
影响因子:16.2
doi:10.1161/CIRCRESAHA.125.326570
Wu, Tianyu; Tee, Nicole G Z; Siu, Yiu Yan; Tornatore, Anna; Bhattacharjee, Abhishek; Koconis, James; Loo, Sze Jie; Su, Liping; Li, Binjie; Ye, Lei; Bursac, Nenad
Human
发表日期：2025
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Human Myobundle Platform for Studying the Role of Notch Signaling in Satellite Cell Phenotype and Function

利用人肌束平台研究Notch信号通路在卫星细胞表型和功能中的作用

期刊:Advanced Healthcare Materials
影响因子:9.6
doi:10.1002/adhm.202404695
Broer, Torie; Tsintolas, Nick; Hammond, Stewart; Helfer, Abbigail; Lee, Joonbum; Purkey, Karly; DeLuca, Sophia; Khodabukus, Alastair; Bursac, Nenad
信号转导
细胞生物学
Human
Notch
发表日期：2025
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Engineered Cardiac Tissues as a Platform for CRISPR-Based Mitogen Discovery.

工程化心脏组织作为基于 CRISPR 的促分裂原发现平台

期刊:Advanced Healthcare Materials
影响因子:9.6
doi:10.1002/adhm.202402201
DeLuca Sophia, Strash Nicholas, Chen Yifan, Patsy Marisa, Myers Ashley, Tejeda Libertad, Broders Sarah, Miranda Amber, Jiang Xixian, Bursac Nenad
心血管
发表日期：2025
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Spatial and longitudinal tracking of enhancer-AAV vectors that target transgene expression to injured mouse myocardium

对靶向转基因表达至受损小鼠心肌的增强子-AAV载体进行空间和纵向追踪

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.107148
Wolfson, David W; Hull, Joshua A; Li, Yongwu; Gonzalez, Trevor J; Jayaram, Mourya D; Devlin, Garth W; Cigliola, Valentina; Oonk, Kelsey A; Rosales, Alan; Bursac, Nenad; Asokan, Aravind; Poss, Kenneth D
发表日期：2025
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Effects of Pharmacological Polyploidization in Human iPSC-Derived Cardiomyocytes

药物多倍体化对人诱导多能干细胞来源心肌细胞的影响

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.124.040497
Strash, Nicholas; Patsy, Marisa; DeLuca, Sophia; Helfer, Abbigail; Jiang, Xixian; Wu, Tianyu; Bursac, Nenad
发育与干细胞
细胞生物学
干细胞
Human
发表日期：2025
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Spatial and longitudinal tracking of enhancer-AAV vectors that target transgene expression to injured mouse myocardium

对靶向转基因表达至受损小鼠心肌的增强子-AAV载体进行空间和纵向追踪

期刊:
影响因子:
doi:10.1101/2025.04.28.651096
Wolfson, David W; Hull, Joshua A; Li, Yongwu; Gonzalez, Trevor J; Jayaram, Mourya D; Devlin, Garth W; Cigliola, Valentina; Oonk, Kelsey A; Rosales, Alan; Bursac, Nenad; Asokan, Aravind; Poss, Kenneth D
发表日期：2025
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