Pluripotent Cells Expressing APOE4 Exhibit a Pronounced Pro-Apoptotic Phenotype Accompanied by Markers of Hyperinflammation and a Blunted NF-κB Response
表达APOE4的多能干细胞表现出明显的促凋亡表型,并伴有过度炎症标志物和NF-κB反应减弱。
期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26199283
Schulten, Wiebke; Czaniera, Nele Johanne; Buschheuer, Anna Lena; Liermann, Antonia; Wiegand, Axel; Kaltschmidt, Barbara; Kaltschmidt, Christian
发育与干细胞
炎症
表观遗传
凋亡
炎症/感染
NF-κB
APOE
干细胞
细胞生物学