日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice

小鼠早期妊娠中子宫成纤维细胞的KDM6B依赖性表观遗传编程调控分娩时间

Tara I McIntyre ,Omar Valdez ,Nathan P Kochhar ,Brittany Davidson ,Bushra Samad ,Longhui Qiu ,Kenneth Hu ,Alexis J Combes ,Adrian Erlebacher

Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment

肿瘤相关巨噬细胞通过胶原沉积和乳腺癌微环境的代谢重编程来限制CD8+ T细胞的功能。

Kevin M Tharp ,Kelly Kersten ,Ori Maller ,Greg A Timblin ,Connor Stashko ,Fernando P Canale ,Rosa E Menjivar ,Mary-Kate Hayward ,Ilona Berestjuk ,Johanna Ten Hoeve ,Bushra Samad ,Alastrair J Ironside ,Marina Pasca di Magliano ,Alexander Muir ,Roger Geiger ,Alexis J Combes ,Valerie M Weaver

Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes

转移性淋巴结中,人类区域淋巴结中针对癌症免疫疗法的动态 CD8+ T 细胞反应受到破坏。

Maha K Rahim ,Trine Line H Okholm ,Kyle B Jones ,Elizabeth E McCarthy ,Candace C Liu ,Jacqueline L Yee ,Stanley J Tamaki ,Diana M Marquez ,Iliana Tenvooren ,Katherine Wai ,Alexander Cheung ,Brittany R Davidson ,Vrinda Johri ,Bushra Samad ,William E O'Gorman ,Matthew F Krummel ,Annemieke van Zante ,Alexis J Combes ,Michael Angelo ,Lawrence Fong ,Alain P Algazi ,Patrick Ha ,Matthew H Spitzer

Transcriptional space-time mapping identifies concerted immune and stromal cell patterns and gene programs in wound healing and cancer

转录时空图谱揭示了伤口愈合和癌症过程中免疫细胞和基质细胞的协同模式和基因程序。

Kenneth H Hu ,Nicholas F Kuhn ,Tristan Courau ,Jessica Tsui ,Bushra Samad ,Patrick Ha ,Johannes R Kratz ,Alexis J Combes ,Matthew F Krummel

Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma

肿瘤细胞异质性驱动鳞状细胞皮肤癌肿瘤内免疫反应的空间组织

Miho Tanaka, Lotus Lum, Kenneth Hu, Cecilia Ledezma-Soto, Bushra Samad, Daphne Superville, Kenneth Ng, Zoe Adams, Kelly Kersten, Lawrence Fong, Alexis J Combes, Matthew Krummel, Melissa Reeves

Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer

癌症中巨噬细胞与耗竭CD8+ T细胞之间的时空共依赖性

Kelly Kersten ,Kenneth H Hu ,Alexis J Combes ,Bushra Samad ,Tory Harwin ,Arja Ray ,Arjun Arkal Rao ,En Cai ,Kyle Marchuk ,Jordan Artichoker ,Tristan Courau ,Quanming Shi ,Julia Belk ,Ansuman T Satpathy ,Matthew F Krummel

Discovering dominant tumor immune archetypes in a pan-cancer census

在泛癌普查中发现主要的肿瘤免疫原型

Alexis J Combes ,Bushra Samad ,Jessica Tsui ,Nayvin W Chew ,Peter Yan ,Gabriella C Reeder ,Divyashree Kushnoor ,Alan Shen ,Brittany Davidson ,Andrea J Barczak ,Michael Adkisson ,Austin Edwards ,Mohammad Naser ,Kevin C Barry ,Tristan Courau ,Taymour Hammoudi ,Rafael J Argüello ,Arjun Arkal Rao ,Adam B Olshen ,Jenny Zhan ,Katelyn C Davis ,Robin K Kelley ,Jocelyn S Chapman ,Chloe E Atreya ,Amar Patel ,Adil I Daud ,Patrick Ha ,Aaron A Diaz ,Johannes R Kratz ,Eric A Collisson ,Gabriela K Fragiadakis ,David J Erle ,Alexandre Boissonnas ,Saurabh Asthana ,Vincent Chan ,Matthew F Krummel

Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer

肿瘤单核细胞向巨噬细胞分化的整体表征整合了肾癌中不同的免疫表型

Adriana M Mujal # ,Alexis J Combes # ,Arjun A Rao # ,Mikhail Binnewies # ,Bushra Samad ,Jessica Tsui ,Alexandre Boissonnas ,Joshua L Pollack ,Rafael J Argüello ,Maxwell V Meng ,Sima P Porten ,Megan K Ruhland ,Kevin C Barry ,Vincent Chan ,Matthew F Krummel

SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution

SCENITH:一种基于流式细胞术的单细胞分辨率能量代谢功能分析方法

Rafael J Argüello ,Alexis J Combes ,Remy Char ,Julien-Paul Gigan ,Ania I Baaziz ,Evens Bousiquot ,Voahirana Camosseto ,Bushra Samad ,Jessica Tsui ,Peter Yan ,Sebastien Boissonneau ,Dominique Figarella-Branger ,Evelina Gatti ,Emeline Tabouret ,Matthew F Krummel ,Philippe Pierre

A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments

自然杀伤细胞-树突状细胞轴定义了对免疫检查点疗法有反应的肿瘤微环境

Kevin C Barry ,Joy Hsu ,Miranda L Broz ,Francisco J Cueto ,Mikhail Binnewies ,Alexis J Combes ,Amanda E Nelson ,Kimberly Loo ,Raj Kumar ,Michael D Rosenblum ,Michael D Alvarado ,Denise M Wolf ,Dusan Bogunovic ,Nina Bhardwaj ,Adil I Daud ,Patrick K Ha ,William R Ryan ,Joshua L Pollack ,Bushra Samad ,Saurabh Asthana ,Vincent Chan ,Matthew F Krummel