Lipid droplet targeting of the lipase coactivator ABHD5 and the fatty liver disease-causing variant PNPLA3 I148M is required to promote liver steatosis.
脂肪酶共激活因子 ABHD5 和导致脂肪肝疾病的变异体 PNPLA3 I148M 靶向脂滴是促进肝脏脂肪变性的必要条件
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.108186
Teskey Grace, Tiwari Nivedita, Butcko Andrew J, Kumar Amit, Yadav Anuradha, Huang Yu-Ming M, Kelly Christopher V, Granneman James G, Perfield James W, Mottillo Emilio P
