日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Human iPSC-derived glutamatergic neurons with pathogenic KCNQ2 variants display hyperactive bursting phenotypes

携带致病性KCNQ2变异的人类iPSC衍生谷氨酸能神经元表现出过度活跃的爆发性表型

期刊:Neurobiology of Disease
影响因子:5.6
doi:10.1016/j.nbd.2025.107126
Sundberg, Maria; Shum, Carole; Norabuena, Erika M; Makhortova, Nina R; Chen, Cidi; Yu, Lucy; Wightman, Emma V; Kim, Kristina; Han, Sang Yeon; Howe, Jennifer; Poduri, Annapurna; Buttermore, Elizabeth D; Scherer, Stephen W; Sahin, Mustafa
KCNQ2
Human
神经科学
发表日期：2025
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Validation of human sensory neurons derived from inducible pluripotent stem cells as a model for latent infection and reactivation by herpes simplex virus 1.

验证由诱导多能干细胞衍生的人类感觉神经元作为单纯疱疹病毒1型潜伏感染和再激活模型的有效性

期刊:mBio
影响因子:4.7
doi:10.1128/mbio.01871-25
Oh Hyung Suk, Chou Shu-Fan, Raja Priya, Shim Jaehoon, Das Biswajit, Pesola Jean M, Romero Nicolás, Lee Jennifer S, Ng Alex, Buttermore Elizabeth D, Church George, Woolf Clifford J, Coen Donald M, Knipe David M
神经科学
Human
发表日期：2025
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mTORC1-selective inhibitors rescue cellular phenotypes in TSC iPSC-derived neurons.

mTORC1选择性抑制剂可挽救TSC iPSC衍生神经元的细胞表型

期刊:Frontiers in Neuroscience
影响因子:3.2
doi:10.3389/fnins.2025.1595880
Buttermore Elizabeth D, Srinivasan Gayathri Rajaram, Jumo Hellen, Swanson Amanda C, O'Kelly Benjamin, Makhortova Nina R, Sahin Mustafa, Tzannis Stelios T
神经科学
细胞生物学
mTOR
发表日期：2025
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High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia

高内涵筛选鉴定出一种小分子，该小分子可恢复AP-4相关遗传性痉挛性截瘫神经元模型中AP-4依赖性蛋白质运输。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-023-44264-1
Afshin Saffari ，Barbara Brechmann ，Cedric Böger ，Wardiya Afshar Saber ，Hellen Jumo ，Dosh Whye ，Delaney Wood ，Lara Wahlster ，Julian E Alecu ，Marvin Ziegler ，Marlene Scheffold ，Kellen Winden ，Jed Hubbs ，Elizabeth D Buttermore ，Lee Barrett ，Georg H H Borner ，Alexandra K Davies ，Darius Ebrahimi-Fakhari ，Mustafa Sahin
神经科学
发表日期：2024
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Rigor and reproducibility in human brain organoid research: Where we are and where we need to go

人脑类器官研究的严谨性和可重复性：现状与未来方向

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2024.04.008
Sandoval, Soraya O; Cappuccio, Gerarda; Kruth, Karina; Osenberg, Sivan; Khalil, Saleh M; Méndez-Albelo, Natasha M; Padmanabhan, Krishnan; Wang, Daifeng; Niciu, Mark J; Bhattacharyya, Anita; Stein, Jason L; Sousa, André M M; Waxman, Elisa A; Buttermore, Elizabeth D; Whye, Dosh; Sirois, Carissa L; Williams, Aislinn; Maletic-Savatic, Mirjana; Zhao, Xinyu
3D/类器官
神经科学
发表日期：2024
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ALDH5A1-deficient iPSC-derived excitatory and inhibitory neurons display cell type specific alterations

ALDH5A1缺陷型iPSC衍生的兴奋性和抑制性神经元表现出细胞类型特异性改变

期刊:Neurobiology of Disease
影响因子:5.1
doi:10.1016/j.nbd.2023.106386
Wardiya Afshar-Saber ,Nicole A Teaney ,Kellen D Winden ,Hellen Jumo ,Xutong Shi ,Gabrielle McGinty ,Jed Hubbs ,Cidi Chen ,Itay Tokatly Latzer ,Federico Gasparoli ,Darius Ebrahimi-Fakhari ,Elizabeth D Buttermore ,Jean-Baptiste Roullet ,Phillip L Pearl ,Mustafa Sahin
ALDH
细胞生物学
神经科学
发表日期：2024
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Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional properties

从具有 GNAO1 p.G203R 变体的患者来源的 iPSC 中获得的皮质神经元表现出改变的分化和功能特性

期刊:Heliyon
影响因子:3.4
doi:10.1016/j.heliyon.2024.e26656
Maria Cristina Benedetti, Tiziano D'andrea, Alessio Colantoni, Denis Silachev, Valeria de Turris, Zaira Boussadia, Valentina A Babenko, Egor A Volovikov, Lilia Belikova, Alexandra N Bogomazova, Rita Pepponi, Dosh Whye, Elizabeth D Buttermore, Gian Gaetano Tartaglia, Maria A Lagarkova, Vladimir L Kat
神经
发表日期：2024
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Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders

利用人类诱导多能干细胞、功能分析和机器学习的潜力来治疗神经发育障碍

期刊:Frontiers in Neuroscience
影响因子:3.2
doi:10.3389/fnins.2024.1524577
Yang, Ziqin; Teaney, Nicole A; Buttermore, Elizabeth D; Sahin, Mustafa; Afshar-Saber, Wardiya
细胞生物学
发育与干细胞
神经科学
干细胞
发表日期：2024
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Generation and characterization of six human induced pluripotent stem cell lines (hiPSCs) from three individuals with SSADH Deficiency and CRISPR-corrected isogenic controls

从三名患有SSADH缺陷症的个体及其CRISPR校正的同基因对照中生成并鉴定了六株人诱导多能干细胞系（hiPSCs）。

期刊:Stem Cell Research
影响因子:0.8
doi:10.1016/j.scr.2024.103424
Wardiya Afshar-Saber,Cidi Chen,Nicole A Teaney,Kristina Kim,Ziqin Yang,Federico M Gasparoli,Darius Ebrahimi-Fakhari,Elizabeth D Buttermore,Ivy Pin-Fang Chen,Phillip L Pearl,Mustafa Sahin
Human
细胞生物学
发育与干细胞
干细胞
发表日期：2024
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Combining Off-flow, a Nextflow-coded program, and whole genome sequencing reveals unintended genetic variation in CRISPR/Cas-edited iPSCs

结合 Off-flow、Nextflow 编码程序和全基因组测序揭示了 CRISPR/Cas 编辑的 iPSC 中的意外遗传变异

期刊:Computational and Structural Biotechnology Journal
影响因子:4.4
doi:10.1016/j.csbj.2023.12.036
Carole Shum, Sang Yeon Han, Bhooma Thiruvahindrapuram, Zhuozhi Wang, Jill de Rijke, Benjamin Zhang, Maria Sundberg, Cidi Chen, Elizabeth D Buttermore, Nina Makhortova, Jennifer Howe, Mustafa Sahin, Stephen W Scherer
发表日期：2023
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