日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

VX-445 (elexacaftor) inhibits chloride secretion across human bronchial epithelial cells by directly blocking KCa3.1 channels

VX-445(依来卡托)通过直接阻断KCa3.1通道抑制人支气管上皮细胞的氯离子分泌。

Kolski-Andreaco, Aaron; Balut, Corina M; Green, Matthew D; Sembrat, John; Bridges, Robert J; Singh, Ashvani K; Tse, Chris; Butterworth, Michael B; Devor, Daniel C

Dysregulated DnaB unwinding induces replisome decoupling and daughter strand gaps that are countered by RecA polymerization

失调的 DnaB 解旋会诱导复制体解偶联和子链间隙,而 RecA 聚合则会抵消这种间隙

Megan S Behrmann, Himasha M Perera, Malisha U Welikala, Jacquelynn E Matthews, Lauren J Butterworth, Michael A Trakselis

Potentiation of BKCa channels by cystic fibrosis transmembrane conductance regulator correctors VX-445 and VX-121.

囊性纤维化跨膜电导调节剂 VX-445 和 VX-121 可增强 BKCa 通道

Kolski-Andreaco Aaron, Taiclet Stefanie, Myerburg Michael M, Sembrat John, Bridges Robert J, Straub Adam C, Wills Zachary P, Butterworth Michael B, Devor Daniel C

MicroRNA-19 is regulated by aldosterone in a sex-specific manner to alter kidney sodium transport

microRNA-19 受醛固酮以性别特异性方式调控,从而改变肾脏钠转运。

Farrell, Corinne E; Liu, Xiaoning; Yagan, Nejla Ozbaki; Suda, Amanda C; Cerqueira, Debora M; Bodnar, Andrew J; Kashlan, Ossama B; Subramanya, Arohan R; Ho, Jacqueline; Butterworth, Michael B

An optimised patient-derived explant platform for breast cancer reflects clinical responses to chemotherapy and antibody-directed therapy

针对乳腺癌的优化患者来源组织块移植平台能够反映化疗和抗体靶向治疗的临床反应。

Demetriou, Constantinos; Abid, Naila; Butterworth, Michael; Lezina, Larissa; Sandhu, Pavandeep; Howells, Lynne; Powley, Ian R; Pringle, James H; Sidat, Zahirah; Qassid, Omar; Purnell, Dave; Kaushik, Monika; Duckworth, Kaitlin; Hartshorn, Helen; Thomas, Anne; Shaw, Jacqui A; MacFarlane, Marion; Pritchard, Catrin; Miles, Gareth J

Non-coding RNAs and the mineralocorticoid receptor in the kidney

肾脏中的非编码RNA和盐皮质激素受体

Butterworth, Michael B

The tale of two (distal nephron) cell types

两种(远端肾单位)细胞类型的故事

Butterworth, Michael B

Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action

选择性剪接的富含脯氨酸的盒式结构将WNK1与醛固酮作用联系起来

Roy, Ankita; Al-Qusairi, Lama; Donnelly, Bridget F; Ronzaud, Caroline; Marciszyn, Allison L; Gong, Fan; Chang, Y P Christy; Butterworth, Michael B; Pastor-Soler, Núria M; Hallows, Kenneth R; Staub, Olivier; Subramanya, Arohan R

MicroRNAs and the regulation of aldosterone signaling in the kidney

微小RNA与肾脏醛固酮信号传导的调控

Butterworth, Michael B

Corrigendum for the paper ‘North–South divide: contrasting impacts of climate change on crop yields in Scotland and England’

论文《南北差异:气候变化对苏格兰和英格兰作物产量的不同影响》的勘误

Straw, Andrew D; Branson, Kristin; Neumann, Titus R; Dickinson, Michael H; Butterworth, Michael H; Semenov, Mikhail A; Barnes, Andrew; Moran, Dominic; West, Jonathan S; Fitt, Bruce D L