日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure-activity relationship profiling of N-substituted 8-trifluoromethyl-9H-purin-6-amines as mitochondrial protonophores

N-取代的8-三氟甲基-9H-嘌呤-6-胺作为线粒体质子载体的构效关系分析

Krinos, Emily L; Fields, Rei J; DeLuca, Isabella M; Foutz, Mary A; Li, Catherine; Hargett, Stefan R; Beretta, Martina; Zhou, Mingyan; Shrestha, Riya; Gwinn, Reilly K; Byrne, Frances L; Hoehn, Kyle L; Santos, Webster L

Diverse actions of 15 structurally unrelated mitochondrial uncouplers in cells and mice

15种结构不相关的线粒体解偶联剂在细胞和小鼠中的不同作用

Shah, Divya P; Vancuylenburg, Calum S; Olzomer, Ellen M; Chen, Sing-Young; Grams, Robert J; Beretta, Martina; Byrne, Frances L; Santos, Webster L; Hoehn, Kyle L

Isotype-selective roles of hepatic acetyl-CoA carboxylases in a mouse model of fatty liver disease.

肝脏乙酰辅酶A羧化酶在脂肪肝疾病小鼠模型中的同型选择性作用。

Beretta Martina, Vancuylenburg Calum S, Shrestha Riya, Olzomer Ellen M, Osborne Brenna, Zhou Mingyan, Zhang Suri, Hargreaves Adam, Byrne Frances L, Hoehn Kyle L

Design, Synthesis, and Biological Evaluation of Naphthoquinone Salts as Anticancer Agents.

萘醌盐作为抗癌剂的设计、合成和生物学评价

Cheng Yao, Yu Tsz Tin, Olzomer Ellen M, Hoehn Kyle L, Byrne Frances L, Kumar Naresh, Black David StC

Design, synthesis and biological evaluation of naphthalene-1,4-dione analogues as anticancer agents.

萘-1,4-二酮类似物作为抗癌剂的设计、合成和生物学评价

Cheng Yao, Yu Tsz Tin, Olzomer Ellen M, Beretta Martina, Katen Alice, Su Jacky, Jones John Patrick, Black David StC, Hoehn Kyle L, Byrne Frances L, Kumar Naresh

Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice

肝脏选择性咪唑并吡嗪类线粒体解偶联剂SHD865可逆转小鼠的肥胖和葡萄糖耐受不良

Beretta, Martina; Dai, Yumin; Olzomer, Ellen M; Vancuylenburg, Calum S; Santiago-Rivera, José A; Philp, Ashleigh M; Hargett, Stefan R; Li, Keyong; Shah, Divya P; Chen, Sing-Young; Alexopoulos, Stephanie J; Li, Catherine; Harris, Thurl E; Lee, Brendan; Wathier, Michel; Cermak, Jennifer M; Tucker, Simon P; Turner, Nigel; Bayliss, Douglas A; Philp, Andrew; Byrne, Frances L; Santos, Webster L; Hoehn, Kyle L

Beneficial effects of MGL-3196 and BAM15 combination in a mouse model of fatty liver disease.

MGL-3196 和 BAM15 联合用药对小鼠脂肪肝疾病模型具有有益作用

Zhou Mingyan, Li Catherine, Byrne Frances L, Vancuylenburg Calum S, Olzomer Ellen M, Hargreaves Adam, Wu Lindsay E, Shackel Nicholas A, Santos Webster L, Hoehn Kyle L

Investigating the Expression and Function of the Glucose Transporter GLUT6 in Obesity.

研究肥胖症中葡萄糖转运蛋白GLUT6的表达和功能

Chen Sing-Young, Olzomer Ellen M, Beretta Martina, Cantley James, Nunemaker Craig S, Hoehn Kyle L, Byrne Frances L

Exploring the therapeutic potential of mitochondrial uncouplers in cancer

探索线粒体解偶联剂在癌症治疗中的应用潜力

Shrestha, Riya; Johnson, Edward; Byrne, Frances L

Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis

短暂性间歇性高血糖通过促进髓系造血加速动脉粥样硬化

Flynn, Michelle C; Kraakman, Michael J; Tikellis, Christos; Lee, Man K S; Hanssen, Nordin M J; Kammoun, Helene L; Pickering, Raelene J; Dragoljevic, Dragana; Al-Sharea, Annas; Barrett, Tessa J; Hortle, Fiona; Byrne, Frances L; Olzomer, Ellen; McCarthy, Domenica A; Schalkwijk, Casper G; Forbes, Josephine M; Hoehn, Kyle; Makowski, Liza; Lancaster, Graeme I; El-Osta, Assam; Fisher, Edward A; Goldberg, Ira J; Cooper, Mark E; Nagareddy, Prabhakara R; Thomas, Merlin C; Murphy, Andrew J