日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CNS-targeted base editing of the major late-onset Tay-Sachs mutation alleviates disease in mice.

针对中枢神经系统的主要迟发性泰-萨克斯病突变进行碱基编辑可缓解小鼠的疾病

Allende Maria L, Kono Mari, Lee Y Terry, Olmsted Samantha M, Huso Vienna, Bakir Jenna Y, Pratto Florencia, Li Cuiling, Byrnes Colleen, Tuymetova Galina, Zhu Hongling, Tifft Cynthia J, Proia Richard L

Clearance of Hepatitis C Viremia During Direct-Acting Antiviral Therapy Leads to Rapid Changes in Lipid and Lipoprotein Metabolism

直接抗病毒治疗期间丙型肝炎病毒血症的清除会导致脂质和脂蛋白代谢的快速变化。

Sarrafan-Chaharsoughi, Zahra; Takyar, Varun; Auh, Sungyoung; Nee, Gavin; Alawad, Ahmad; Abel, Brent S; Kapuria, Devika; Byrnes, Colleen; Wolska, Anna; Kleiner, David E; Shamburek, Robert; Remaley, Alan T; Ghany, Marc G

1-Deoxysphingolipids Require Very-Long-Chain Ceramide Synthesis to Induce ER Stress and Neurotoxicity

1-脱氧鞘脂需要极长链神经酰胺合成才能诱导内质网应激和神经毒性

Byrnes, Colleen; Clarke, Benjamin A; Zhu, Hongling; Majumder, Saurav; Kono, Mari; Proia, Richard L

The Complement Regulator Susd4 Influences Nervous-System Function and Neuronal Morphology in Mice

补体调节因子Susd4影响小鼠的神经系统功能和神经元形态

Zhu, Hongling; Meissner, Laura E; Byrnes, Colleen; Tuymetova, Galina; Tifft, Cynthia J; Proia, Richard L

Iron dose-dependent differentiation and enucleation of human erythroblasts in serum-free medium

在无血清培养基中,铁剂量依赖性地诱导人红细胞分化和去核。

Byrnes, Colleen; Lee, Y Terry; Meier, Emily R; Rabel, Antoinette; Sacks, David B; Miller, Jeffery L

Absolute Reticulocyte Count Acts as a Surrogate for Fetal Hemoglobin in Infants and Children with Sickle Cell Anemia

绝对网织红细胞计数可作为镰状细胞贫血症患儿胎儿血红蛋白的替代指标

Meier, Emily Riehm; Byrnes, Colleen; Weissman, Maxine; Lee, Y Terry; Miller, Jeffery L

Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients.

血浆非转铁蛋白结合铁的生成机制:通过比较输血治疗的钻石-布莱克范贫血与镰状细胞贫血和地中海贫血患者,获得新的见解

Porter John B, Walter Patrick B, Neumayr Lynne D, Evans Patricia, Bansal Sukhvinder, Garbowski Maciej, Weyhmiller Marcela G, Harmatz Paul R, Wood John C, Miller Jeffery L, Byrnes Colleen, Weiss Guenter, Seifert Markus, Grosse Regine, Grabowski Dagmar, Schmidt Angelica, Fischer Roland, Nielsen Peter, Niemeyer Charlotte, Vichinsky Elliott

Increased reticulocytosis during infancy is associated with increased hospitalizations in sickle cell anemia patients during the first three years of life

婴儿期网织红细胞增多与镰状细胞贫血患者在生命最初三年内的住院率增加相关。

Meier, Emily Riehm; Byrnes, Colleen; Lee, Y Terry; Wright, Elizabeth C; Schechter, Alan N; Luban, Naomi L C; Miller, Jeffery L

Calpastatin controls polymicrobial sepsis by limiting procoagulant microparticle release

钙蛋白酶抑制剂通过限制促凝微粒的释放来控制多微生物败血症。

Zafrani, Lara; Gerotziafas, Grigoris; Byrnes, Colleen; Hu, Xuzhen; Perez, Joelle; Lévi, Charlène; Placier, Sandrine; Letavernier, Emmanuel; Leelahavanichkul, Asada; Haymann, Jean-philippe; Elalamy, Ismail; Miller, Jeffrey L; Star, Robert A; Yuen, Peter S T; Baud, Laurent

Expression patterns of fetal hemoglobin in sickle cell erythrocytes are both patient- and treatment-specific during childhood

儿童时期,镰状细胞红细胞中胎儿血红蛋白的表达模式既具有患者特异性,也具有治疗特异性。

Meier, Emily Riehm; Byrnes, Colleen; Weissman, Maxine; Noel, Pierre; Luban, Naomi L C; Miller, Jeffery L