日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Real-World Concordance between Germline and Tumour BRCA1/2 Status in Epithelial Ovarian Cancer

上皮性卵巢癌中生殖系和肿瘤 BRCA1/2 状态之间的真实世界一致性

Robert D Morgan, George J Burghel, Helene Schlecht, Andrew R Clamp, Jurjees Hasan, Claire L Mitchell, Zena Salih, Joseph Shaw, Sudha Desai, Gordon C Jayson, Emma R Woodward, D Gareth R Evans

Plasma Tie2 trajectories identify vascular response criteria for VEGF inhibitors across advanced biliary tract, colorectal and ovarian cancers

血浆Tie2轨迹可确定晚期胆道癌、结直肠癌和卵巢癌中VEGF抑制剂的血管反应标准

Zhou, C; O'Connor, J; Backen, A; Valle, J W; Bridgewater, J; Dive, C; Jayson, G C

c-MET/VEGFR-2 co-localisation impacts on survival following bevacizumab therapy in epithelial ovarian cancer: an exploratory biomarker study of the phase 3 ICON7 trial

c-MET/VEGFR-2 共定位对上皮性卵巢癌贝伐单抗治疗后生存的影响:III 期 ICON7 试验的探索性生物标志物研究

Robert D Morgan #, Cristina Ferreras #, Isabel Peset, Egle Avizienyte, Andrew G Renehan, Richard J Edmondson, Alexander D Murphy, Shibani Nicum, Thomas Van Brussel, Andrew R Clamp, Diether Lambrechts, Cong Zhou #, Gordon C Jayson #0

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

卵巢癌体外模型的活体生物样本库揭示了显著的有丝分裂异质性

Louisa Nelson # ,Anthony Tighe # ,Anya Golder ,Samantha Littler ,Bjorn Bakker ,Daniela Moralli ,Syed Murtuza Baker ,Ian J Donaldson ,Diana C J Spierings ,René Wardenaar ,Bethanie Neale ,George J Burghel ,Brett Winter-Roach ,Richard Edmondson ,Andrew R Clamp ,Gordon C Jayson ,Sudha Desai ,Catherine M Green ,Andy Hayes ,Floris Foijer ,Robert D Morgan ,Stephen S Taylor

Duration and clinical features of cardiac arrest predict early severe cerebral edema

心脏骤停的持续时间和临床特征可预测早期严重脑水肿。

Esdaille, C Jayson; Coppler, Patrick J; Faro, John W; Weisner, Zachary M; Condle, Joseph P; Elmer, Jonathan; Callaway, Clifton W

Synthetic Site-Selectively Mono-6-O-Sulfated Heparan Sulfate Dodecasaccharide Shows Anti-Angiogenic Properties In Vitro and Sensitizes Tumors to Cisplatin In Vivo

合成位点选择性单-6-O-硫酸化硫酸肝素十二糖在体外表现出抗血管生成特性,并在体内增强肿瘤对顺铂的敏感性

Egle Avizienyte, Claire L Cole, Graham Rushton, Gavin J Miller, Antonella Bugatti, Marco Presta, John M Gardiner, Gordon C Jayson

Modular synthesis of heparin-related tetra-, hexa- and octasaccharides with differential o-6 protections: programming for regiodefined 6-o-modifications

具有差异 o-6 保护的肝素相关四糖、六糖和八糖的模块化合成:区域定义的 6-o-修饰的编程

Marek Baráth, Steen U Hansen #, Charlotte E Dalton #, Gordon C Jayson, Gavin J Miller, John M Gardiner

Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signaling

卵巢癌细胞硫酸肝素 6-O-磺基转移酶调节由肝素结合表皮生长因子 (EGF) 样生长因子/EGF 受体信号诱导的血管生成程序

Claire L Cole, Graham Rushton, Gordon C Jayson, Egle Avizienyte

Endothelial heparan sulfate 6-O-sulfation levels regulate angiogenic responses of endothelial cells to fibroblast growth factor 2 and vascular endothelial growth factor

内皮肝素硫酸盐 6-O-硫酸化水平调节内皮细胞对成纤维细胞生长因子 2 和血管内皮生长因子的血管生成反应

Cristina Ferreras, Graham Rushton, Claire L Cole, Muhammad Babur, Brian A Telfer, Toin H van Kuppevelt, John M Gardiner, Kaye J Williams, Gordon C Jayson, Egle Avizienyte

Biomarkers of angiogenesis and their role in the development of VEGF inhibitors

血管生成生物标志物及其在VEGF抑制剂研发中的作用

Murukesh, N; Dive, C; Jayson, G C