Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in vero cells or human liver cells and attenuated in mice
对登革病毒4型进行化学诱变,可产生在Vero细胞或人肝细胞中对温度敏感、在小鼠中毒力减弱的突变病毒。
期刊:Journal of Virology
影响因子:3.8
doi:10.1128/JVI.75.20.9731-9740.2001
Blaney, J E Jr; Johnson, D H; Firestone, C Y; Hanson, C T; Murphy, B R; Whitehead, S S